Human CKMB heterodimer, C-Flag, StrepII Tag&C-His Tag Protein

RMB: 599 特惠 1599 1599

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Catalog# HA210947

Human CKMB heterodimer, C-Flag, StrepII Tag&C-His Tag Protein

Product Information

Product name

Human CKMB heterodimer, C-Flag, StrepII Tag&C-His Tag Protein

Catalog No.

HA210947

Predicted molecular mass

46kD and 43kD

Protein construction description

Human CKM (P06732) with both flag and Strep II tag at the C-terminus and human CKB (P12277) with a His tag at the C-terminus are co-expression in E.coli cells.

Accession

P06732,P12277

Protein construction

CKM(2-381)-Flag-StrepII, CKB(1-381)-His

Source

E.coli

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens. Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (Probable). Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

Human CKMB heterodimer, C-Flag, StrepII Tag&C-His Tag Protein

RMB: 599 特惠 1599 1599

产品规格

联系我们

Product Information

Product name

Catalog No.

Predicted molecular mass

Protein construction description

Accession

Protein construction

Source

Bio Activity

Purity

Endotoxin

Formulation

Species

Background

Usage guide

Shipping

Storage

Reconstitution

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