Human IL-7, C-His, Flag Tag

RMB: 599 特惠 1619 1619

产品规格

20μg

50μg

100μg

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Catalog# HA210595

Human IL-7, C-His, Flag Tag

Product Information

Product name

Human IL-7, C-His, Flag Tag

Catalog No.

HA210595

Predicted molecular mass

20 kD

Protein construction description

A DNA sequence encoding the human IL-7 protein (P13232) (Asp 26-His 177) was expressed with both His, Flag tag at the C-terminus.

Accession

P13232

Protein construction

IL-7 (26-177) His Flag

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis. Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG. Binding to the receptor leads to activation of various kinases including JAK1 or JAK3 depending on the cell type and subsequently propagation of signals through activation of several downstream signaling pathways including the PI3K/Akt/mTOR or the JAK-STAT5.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.