Human LILRB2/CD85d/ILT4, C-His, Flag Tag (ECD)

RMB: 599 特惠 1619 1619

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20μg

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Catalog# HA210643

Human LILRB2/CD85d/ILT4, C-His, Flag Tag (ECD)

Product Information

Product name

Human LILRB2/CD85d/ILT4, C-His, Flag Tag (ECD)

Catalog No.

HA210643

Predicted molecular mass

50.4 kD

Protein construction description

A DNA sequence encoding the human LILRB2/CD85d/ILT4 protein (Q8N423) (Gln 22-Val 460) was expressed with both His and Flag tag at the C-terminus.

Accession

Q8N423

Protein construction

LILRB2/CD85d/ILT4 (22-460) His Flag

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.