Human IL-29/IFN-lambda 1, Tag Free Protein

RMB: 599 特惠 1619 1619

产品规格

20μg

50μg

100μg

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Catalog# HA210970

Human IL-29/IFN-lambda 1, Tag Free Protein

Product Information

Product name

Human IL-29/IFN-lambda 1, Tag Free Protein

Catalog No.

HA210970

Predicted molecular mass

20.4 kD

Protein construction description

A DNA sequence encoding the human IL-29/IFN-lambda 1 protein (Q8IU54) (Gly 20-Thr 200) was expressed with tag free.

Accession

Q8IU54

Protein construction

IL-29/IFN-lambda 1 (20-200)

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.