CD105 Recombinant Rabbit Monoclonal Antibody [PSH15-96]
Catalog# HA723801
CD105 Recombinant Rabbit Monoclonal Antibody [PSH15-96]
-
FC
-
Human
-
HA751587
不含抗保成分
-
unconjugated
概述
产品名称
CD105 Recombinant Rabbit Monoclonal Antibody [PSH15-96]
抗体类型
Recombinant Rabbit monoclonal Antibody
免疫原
Recombinant protein within human CD105 aa 26-586.
种属反应性
Human
验证应用
FC
分子量
Predicted band size: 71 kDa
阳性对照
U-937.
偶联
unconjugated
克隆号
PSH15-96
反应性数据
| FC | |
|---|---|
| Human |
|
| Mouse | |
| Rat |
产品特性
形态
Liquid
浓度
存放说明
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
存储缓冲液
1*PBS (pH7.4), 1% BSA, 0.2% Proclean 950.
亚型
IgG
纯化方式
Protein A affinity purified.
应用稀释度
-
FC
-
1:1,000
靶点
功能
Endoglin (ENG) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. It is also commonly referred to as CD105, END, FLJ41744, HHT1, ORW and ORW1. It has a crucial role in angiogenesis, therefore, making it an important protein for tumor growth, survival and metastasis of cancer cells to other locations in the body.
背景文献
1. Oladejo M et al. CD105 in the progression and therapy of renal cell carcinoma. Cancer Lett. 2023 Aug
2. Li L et al. CD105: tumor diagnosis, prognostic marker and future tumor therapeutic target. Clin Transl Oncol. 2022 Aug
亚细胞定位
Cell membrane.
UNIPROT
别名
AI528660 antibody
AI662476 antibody
CD 105 antibody
CD105 antibody
CD105 antigen antibody
EGLN_HUMAN antibody
END antibody
Endoglin antibody
Eng antibody
FLJ41744 antibody
展开图片
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☑ Relative expression (RE)
Flow cytometric analysis of LNCaP (left, negative) and U-937 (right, positive) cells labeling CD105.
Cells were washed twice with cold PBS and resuspend. Then stained with the primary antibody (HA723801, 1/1,000) (red) compared with Rabbit IgG Isotype Control (green). After incubation of the primary antibody at +4℃ for an hour, the cells were stained with a iFluor™ 488 conjugate-Goat anti-Rabbit IgG Secondary antibody (HA1121) at 1/1,000 dilution for 30 minutes at +4℃. Unlabelled sample was used as a control (cells without incubation with primary antibody; black).
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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