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CD21 Recombinant Rabbit Monoclonal Antibody [PD00-23]

RMB: 1500

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Catalog# IRS019

CD21 Recombinant Rabbit Monoclonal Antibody [PD00-23]

Application

  • mIHC

Reactivity

  • Human

概述

产品名称

CD21 Recombinant Rabbit Monoclonal Antibody [PD00-23]

抗体类型

Recombinant Rabbit monoclonal Antibody

免疫原

Synthetic peptide within Human CD21 aa 1000 to the C-terminus.

种属反应性

Human

验证应用

mIHC

分子量

Predicted band size: 113 kDa

阳性对照

Human tonsils tissue.

偶联

unconjugated

克隆号

PD00-23

产品特性

形态

Liquid

浓度

1ug/ul

存放说明

Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

存储缓冲液

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

亚型

IgG

纯化方式

Protein A affinity purified.

应用稀释度

  • mIHC

  • 1:100

靶点

功能

This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

背景文献

1. Smith NA. et. al. CD21 (Complement Receptor 2) Is the Receptor for Epstein-Barr Virus Entry into T Cells. J Virol. 2020 May

2. Visentini M. et. al. CD21(low) B cells are predictive markers of new digital ulcers in systemic sclerosis. Clin Exp Immunol. 2021 Aug

亚细胞定位

Cell membrane.

UNIPROT #

SwissProt: P20023 Human

别名

C3DR antibody

CD 21 antibody

CD21 antibody

Complement C3d receptor 2 antibody

Complement C3d receptor antibody

Complement component (3d/Epstein Barr virus) receptor 2 antibody

Complement receptor type 2 antibody

CR antibody

Cr2 antibody

CR2_HUMAN antibody

展开

图片

  • mIHC analysis of human tonsils tissue (Formalin/PFA-fixed paraffin-embedded sections) with Rabbit anti-CD21 antibody (<a href="/products/IRS019" style="font-weight: bold;text-decoration: underline;">IRS019</a>) at 1/100 dilution. The immunostaining was performed with the IRISKit&reg; HyperView mTSA Kit (<a href="/products/MH900206" style="font-weight: bold;text-decoration: underline;">MH900206</a>). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.

    mIHC analysis of human tonsils tissue (Formalin/PFA-fixed paraffin-embedded sections) with Rabbit anti-CD21 antibody (IRS019) at 1/100 dilution. The immunostaining was performed with the IRISKit® HyperView mTSA Kit (MH900206). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.

  • mIHC analysis of human gastric cancer tissue (Formalin/PFA-fixed paraffin-embedded sections) with CD21 (<a href="/products/IRS019" style="font-weight: bold;text-decoration: underline;">IRS019</a>), PD-1, CD14 (<a href="/products/IRS015" style="font-weight: bold;text-decoration: underline;">IRS015</a>), CD38 (<a href="/products/IRS006" style="font-weight: bold;text-decoration: underline;">IRS006</a>), aSMA (<a href="/products/IRS012" style="font-weight: bold;text-decoration: underline;">IRS012</a>) and CK7 (<a href="/products/IRS029" style="font-weight: bold;text-decoration: underline;">IRS029</a>) antibody at 1/100 dilution. The immunostaining was performed with the IRISKit&reg; HyperView mTSA Kit (<a href="/products/MH900206" style="font-weight: bold;text-decoration: underline;">MH900206</a>). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.

    mIHC analysis of human gastric cancer tissue (Formalin/PFA-fixed paraffin-embedded sections) with CD21 (IRS019), PD-1, CD14 (IRS015), CD38 (IRS006), aSMA (IRS012) and CK7 (IRS029) antibody at 1/100 dilution. The immunostaining was performed with the IRISKit® HyperView mTSA Kit (MH900206). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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