RMB: 599 特惠 1500 1500
产品规格
概述
产品名称
beta Tubulin Recombinant Rabbit Monoclonal Antibody [SR25-04]
抗体类型
Recombinant Rabbit monoclonal Antibody
免疫原
Synthetic peptide within Human beta Tubulin aa 308-357 / 444.
种属反应性
Human, Mouse, Rat
验证应用
WB, IF-Cell, IHC-P, FC
分子量
Predicted band size: 50 kDa
阳性对照
HeLa cell lysate, 293T cell lysate, MCF7 cell lysate, SH-SY5Y cell lysate, U-2 OS cell lysate, Jurkat cell lysate, Neuro-2a cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, A549, HeLa, NIH/3T3, PC-12, human fallopian tube tissue, human colon carcinoma tissue, rat kidney tissue, mouse large intestine tissue.
偶联
unconjugated
克隆号
SR25-04
RRID
产品特性
形态
Liquid
存放说明
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
存储缓冲液
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG
纯化方式
Protein A affinity purified.
应用稀释度
-
WB
-
1:20,000-1:100,000
-
IF-Cell
-
1:200-1:1,000
-
IHC-P
-
1:400-1:1,000
-
FC
-
1:500-1:1,000
靶点
功能
Tubulin is one of several members of a small family of globular proteins. The most common members of the tubulin family are α-tubulin and β-tubulin. The beta-tubulin (relative molecular weight about 50 kDa) is counterpart of alpha-tubulin in tubulin heterodimer, it is coded by multiple tubulin genes and it is also posttranslationally modified. Heterogeneity of subunit is concentrated in C-terminal structural domain. Beta-Tubulin may have bound GTP or GDP. Under certain conditions β-tubulin can hydrolyze its bound GTP to GDP plus Pi, release the Pi, and exchange the GDP for GTP.
背景文献
1. "Tumoral and tissue-specific expression of the major human beta-tubulin isotypes."Leandro-Garcia L.J., Leskela S., Landa I., Montero-Conde C., Lopez-Jimenez E., Leton R., .Cytoskeleton 67:214-223(2010).
2. "Five mouse tubulin isotypes and their regulated expression during development."Lewis S.A., Lee M.G.-S., Cowan N.J.J. Cell Biol. 101:852-861(1985).
序列相似性
Belongs to the tubulin family.
组织特异性
Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
翻译后修饰
Some glutamate residues at the C-terminus are polyglutamylated, resulting in polyglutamate chains on the gamma-carboxyl group. Polyglutamylation plays a key role in microtubule severing by spastin (SPAST). SPAST preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity by SPAST increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold.; Some glutamate residues at the C-terminus are monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella). Both polyglutamylation and monoglycylation can coexist on the same protein on adjacent residues, and lowering glycylation levels increases polyglutamylation, and reciprocally. The precise function of monoglycylation is still unclear (Probable).; Phosphorylated on Ser-172 by CDK1 during the cell cycle, from metaphase to telophase, but not in interphase. This phosphorylation inhibits tubulin incorporation into microtubules.
亚细胞定位
Cytoplasm
别名
Beta 4 tubulin antibody
Beta 5 tubulin antibody
BetaTubulin antibody
TBB5_HUMAN antibody
TUBB antibody
TUBB2 antibody
TUBB2A antibody
TUBB5 antibody
tubulin beta 2A antibody
Tubulin beta chain antibody
展开Beta 4 tubulin antibody
Beta 5 tubulin antibody
BetaTubulin antibody
TBB5_HUMAN antibody
TUBB antibody
TUBB2 antibody
TUBB2A antibody
TUBB5 antibody
tubulin beta 2A antibody
Tubulin beta chain antibody
Tubulin beta-5 chain antibody
折叠图片
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Western blot analysis of beta Tubulin on different lysates with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/20,000 dilution.
Lane 1: HeLa cell lysate (15 µg/Lane)
Lane 2: 293T cell lysate (15 µg/Lane)
Lane 3: MCF7 cell lysate (15 µg/Lane)
Lane 4: SH-SY5Y cell lysate (15 µg/Lane)
Lane 5: U-2 OS cell lysate (15 µg/Lane)
Lane 6: Jurkat cell lysate (15 µg/Lane)
Lane 7: Neuro-2a cell lysate (15 µg/Lane)
Lane 8: NIH/3T3 cell lysate (15 µg/Lane)
Lane 9: PC-12 cell lysate (15 µg/Lane)
Lane 10: Mouse brain tissue lysate (20 µg/Lane)
Lane 11: Rat brain tissue lysate (20 µg/Lane)
Predicted band size: 50 kDa
Observed band size: 50 kDa
Exposure time: 1 minute 20 seconds; ECL: K1801;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (ET1602-4) at 1/20,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:100,000 dilution was used for 1 hour at room temperature. -
Immunocytochemistry analysis of A549 cells labeling beta Tubulin with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/500 dilution.
Cells were fixed in 4% paraformaldehyde for 15 minutes at room temperature, permeabilized with 0.1% Triton X-100 in PBS for 15 minutes at room temperature, then blocked with 1% BSA in 10% negative goat serum for 1 hour at room temperature. Cells were then incubated with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/500 dilution in 1% BSA in PBST overnight at 4 ℃. Goat Anti-Rabbit IgG H&L (iFluor™ 488, HA1121) was used as the secondary antibody at 1/1,000 dilution. PBS instead of the primary antibody was used as the secondary antibody only control. Nuclear DNA was labelled in blue with DAPI.
Beta tubulin (HA601187, red) was stained at 1/100 dilution overnight at +4℃. Goat Anti-Mouse IgG H&L (iFluor™ 594, HA1126) was used as the secondary antibody at 1/1,000 dilution. -
Immunocytochemistry analysis of HeLa cells labeling beta Tubulin with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/500 dilution.
Cells were fixed in 4% paraformaldehyde for 15 minutes at room temperature, permeabilized with 0.1% Triton X-100 in PBS for 15 minutes at room temperature, then blocked with 1% BSA in 10% negative goat serum for 1 hour at room temperature. Cells were then incubated with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/500 dilution in 1% BSA in PBST overnight at 4 ℃. Goat Anti-Rabbit IgG H&L (iFluor™ 488, HA1121) was used as the secondary antibody at 1/1,000 dilution. PBS instead of the primary antibody was used as the secondary antibody only control. Nuclear DNA was labelled in blue with DAPI.
Beta tubulin (HA601187, red) was stained at 1/100 dilution overnight at +4℃. Goat Anti-Mouse IgG H&L (iFluor™ 594, HA1126) was used as the secondary antibody at 1/1,000 dilution. -
Immunocytochemistry analysis of NIH/3T3 cells labeling beta Tubulin with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/500 dilution.
Cells were fixed in 4% paraformaldehyde for 15 minutes at room temperature, permeabilized with 0.1% Triton X-100 in PBS for 15 minutes at room temperature, then blocked with 1% BSA in 10% negative goat serum for 1 hour at room temperature. Cells were then incubated with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/500 dilution in 1% BSA in PBST overnight at 4 ℃. Goat Anti-Rabbit IgG H&L (iFluor™ 488, HA1121) was used as the secondary antibody at 1/1,000 dilution. PBS instead of the primary antibody was used as the secondary antibody only control. Nuclear DNA was labelled in blue with DAPI.
Beta tubulin (HA601187, red) was stained at 1/100 dilution overnight at +4℃. Goat Anti-Mouse IgG H&L (iFluor™ 594, HA1126) was used as the secondary antibody at 1/1,000 dilution. -
Immunocytochemistry analysis of PC-12 cells labeling beta Tubulin with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/1,000 dilution.
Cells were fixed in 4% paraformaldehyde for 20 minutes at room temperature, permeabilized with 0.1% Triton X-100 in PBS for 5 minutes at room temperature, then blocked with 1% BSA in 10% negative goat serum for 1 hour at room temperature. Cells were then incubated with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/1,000 dilution in 1% BSA in PBST overnight at 4 ℃. Goat Anti-Rabbit IgG H&L (iFluor™ 594, HA1122) was used as the secondary antibody at 1/1,000 dilution. PBS instead of the primary antibody was used as the secondary antibody only control. Nuclear DNA was labelled in blue with DAPI. -
Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/400 dilution.
The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (ET1602-4) at 1/400 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX. -
Immunohistochemical analysis of paraffin-embedded rat kidney tissue with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/400 dilution.
The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (ET1602-4) at 1/400 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX. -
Immunohistochemical analysis of paraffin-embedded mouse large intestine tissue with Rabbit anti-beta Tubulin antibody (ET1602-4) at 1/400 dilution.
The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (ET1602-4) at 1/400 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX. -
Flow cytometric analysis of NIH/3T3 cells labeling beta Tubulin.
Cells were fixed and permeabilized. Then stained with the primary antibody (ET1602-4, 1ug/ml) (red) compared with Rabbit IgG Isotype Control (green). After incubation of the primary antibody at +4℃ for an hour, the cells were stained with a iFluor™ 488 conjugate-Goat anti-Rabbit IgG Secondary antibody (HA1121) at 1/1,000 dilution for 30 minutes at +4℃. Unlabelled sample was used as a control (cells without incubation with primary antibody; black).
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
引文
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MFAP5 as a promising biomarker for connective tissue disease-associated interstitial lung disease
期刊: Frontiers In Immunology
DOI: 10.3389/fimmu.2025.1642408
IF: 5.9
应用: WB
反应种属: Mouse
发表时间: 2025 Oct
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Galectin-1 Overexpression Protects Damaged Optic Nerve and Visual Function in Mice by Inhibiting the p38/ MAPK–NF-κB Signaling Pathway
期刊: Experimental Eye Research
DOI: 10.1016/j.exer.2025.110689
IF: 2.7
应用: WB
反应种属: Mouse
发表时间: 2025 Oct
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Nuclear transport factor IPO4 modifies localization by PCV2 and facilitates viral replication
期刊: Veterinary Microbiology
DOI: 10.1016/j.vetmic.2025.110749
IF: 2.7
应用: WB
反应种属: Porcine
发表时间: 2025 Oct
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Exosomes miR-369-3p Alleviates Early Brain Injury After Subarachnoid Hemorrhage by Promoting Ferroptosis of M1 Microglia via Inhibiting iNOS/GPX4 Axis
期刊: Brain and Behavior
DOI: 10.1002/brb3.70966
IF: 2.7
应用: WB
反应种属: Mouse
发表时间: 2025 Oct
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Transketolase regulates endoplasmic reticulum stress independent of enzymatic activity in human retinal Müller cells
期刊: Experimental Eye Research
DOI: 10.1016/j.exer.2025.110732
IF: 2.7
应用: WB
反应种属: Mouse,Human
发表时间: 2025 Nov
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Ginsenoside Rb1 Alleviates Atherosclerosis by Modulating Vascular Smooth Muscle Cell Proliferation, Foam Cell Formation, and Autophagy
期刊: Phytomedicine
DOI: 10.1016/j.phymed.2025.157503
IF: 8.3
应用: WB
反应种属: Mouse
发表时间: 2025 Nov
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Interferon-Driven Biomarkers and Synergistic Therapy for PRMT5 Inhibition in Triple-Negative Breast Cancer
期刊: Advanced Science
DOI: 10.1002/advs.202505787
IF: 14.1
应用: WB
反应种属: Human
发表时间: 2025 Nov
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Sphingosine-1-phosphate signalling activates E-Syt1 to facilitate HDL-derived cholesterol transport
期刊: Nature Cell Biology
DOI: 10.1038/s41556-025-01665-2
IF: 17.3
应用: WB
反应种属: Human
发表时间: 2025 May
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Nitrobenzoyl-insulicolide A: a novel dinitrobenzoyl sesquiterpenoid, induces autophagic cell death in small cell lung cancer cells
期刊: Marine Life Science & Technology
DOI: 10.1007/s42995-025-00292-y
IF: 5.8
应用: WB
反应种属: Human
发表时间: 2025 May
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HBV core protein enhances WDR46 stabilization to upregulate NUSAP1 and promote HCC progression
期刊: Hepatology Communications
DOI: 10.1097/HC9.0000000000000680
IF: 5.6
应用: WB
反应种属: Human
发表时间: 2025 May
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Comprehensive systems biology analysis reveals splicing factor contributions to cutaneous melanoma progression
期刊: Scientific Reports
DOI: 10.1038/s41598-025-93695-x
IF: 3.8
应用: WB
反应种属: Human
发表时间: 2025 Mar
-
Targeting NEDD8 in pediatric acute myeloid leukemia: an integrated bioinformatics and experimental approach
期刊: Hematology
DOI: 10.1080/16078454.2025.2478650
IF: 2
应用: WB
反应种属: Human
发表时间: 2025 Mar
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Therapeutic targeting of the Tryptophan-Kynurenine Axis for HTR-8/SVneo trophoblast proliferation and migration in unexplained recurrent spontaneous abortion
期刊: BIOLOGY OF REPRODUCTION
DOI: 10.1093/biolre/ioaf040
IF: 3
应用: WB
反应种属: Human
发表时间: 2025 Mar
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lnc15qD3 expression in the NAc shell regulates the reconsolidation of opioid reward memories
期刊: Progress In Neuro-Psychopharmacology & Biological Psychiatry
DOI: 10.1016/j.pnpbp.2025.111433
IF: 3.9
应用: WB
反应种属: Mouse
发表时间: 2025 Jun
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Jingfang Granules for Diabetic Wound Healing: Insights from Network Pharmacology and Experimental Validation
期刊: Drug Design Development and Therapy
DOI: 10.2147/DDDT.S516298
IF: 5.1
应用: WB
反应种属: Rat
发表时间: 2025 Jun
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NSUN3-Mediated ROS Accumulation Promotes Hepatocellular Carcinoma Proliferation and Activates PI3K/AKT Pathway
期刊: Biochemical Genetics
DOI: 10.1007/s10528-025-11158-4
IF: 1.6
应用: WB
反应种属: Human
发表时间: 2025 Jun
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TIA1-mediated stress granules promote neurodegeneration by sequestering HSP70 mRNA in C9orf72 mice
期刊: Brain
DOI: 10.1093/brain/awaf248
IF: 11.7
应用: WB
反应种属: Mouse
发表时间: 2025 Jul
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ATF7IP/SETDB1-mediated epigenetic programming regulates thymic homing and T lymphopoiesis of hematopoietic progenitors during embryogenesis
期刊: Nature Communications
DOI: 10.1038/s41467-025-61680-7
IF: 15.7
应用: WB
反应种属: Zebrafish
发表时间: 2025 Jul
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Sleep Deprivation Activates a Conserved Lactate-H3K18la-RORα Axis Driving Neutrophilic Inflammation Across Species
期刊: Advanced Science
DOI: 10.1002/advs.202504028
IF: 14.1
应用: WB
反应种属: Human
发表时间: 2025 Jul
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ATF7IP/SETDB1-mediated epigenetic programming regulates thymic homing and T lymphopoiesis of hematopoietic progenitors during embryogenesis
期刊: Nature Communications
DOI: 10.1038/s41467-025-61680-7
IF: 15.7
应用: WB
反应种属: Zebrafish
发表时间: 2025 Jul
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Recombinant human collagen microneedle patch loaded with PRP for diabetic wound treatment
期刊: Journal Of Materials Chemistry B
DOI: 10.1039/D5TB00836K
IF: 5.7
应用: WB
反应种属: Rat,Mouse
发表时间: 2025 Jul
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Astrocytic YAP prevents the glutamate neurotoxicity by upregulation of EAAT2 expression and promotes the gain of stemness in astrocytes in ischemic stroke mice
期刊: Cell Death & Disease
DOI: 10.1038/s41419-025-07806-7
IF: 9.6
应用: WB
反应种属: Mouse
发表时间: 2025 Jul
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ACNO hydrogel enhances diabetic wound healing by modulating the Bcl-2/Bax/Caspase-3/PARP pathway
期刊: International Immunopharmacology
DOI:
IF: 4.8
应用: WB
反应种属: Mouse,Human
发表时间: 2025 Jan
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ACNO hydrogel enhances diabetic wound healing by modulating the Bcl-2/Bax/Caspase-3/PARP pathway
期刊: INTERNATIONAL IMMUNOPHARMACOLOGY
DOI: 10.1016/j.intimp.2024.113997
IF: 4.7
应用: WB
反应种属: Mouse,Human
发表时间: 2025 Jan
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Adropin-Driven Browning: Targeting M2 Macrophages to Combat PCOS
期刊: International Immunopharmacology
DOI: 10.1016/j.intimp.2025.114273
IF: 4.8
应用: WB
反应种属: Mouse
发表时间: 2025 Feb
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ANKRD22 participates in the proinflammatory activities of macrophages in the colon cancer tumor microenvironment
期刊: Cancer Immunology Immunotherapy
DOI: 10.1007/s00262-024-03930-z
IF: 4.6
应用: WB
反应种属: Mouse
发表时间: 2025 Feb
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HDAC6/Trim21 aggravates macrophage inflammatory response and titanium-induced osteolysis via GSDMD signaling pathway
期刊: Journal Of Immunology
DOI: 10.1093/jimmun/vkaf112
IF: 3.4
应用: WB
反应种属: Mouse
发表时间: 2025 Aug
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ERRγ Promotes Multiple Myeloma Survival by Coordinating NF-κB Signaling and Mitochondrial Apoptosis Regulation
期刊: Oncology Research
DOI: 10.32604/or.2025.063700
IF: 4.1
应用: WB
反应种属: Human
发表时间: 2025 Aug
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Evaluated NSUN3 in reticulocytes from HbH-CS disease that reflects cellular stress in erythroblasts
期刊: Annals of Hematology
DOI: 10.1007/s00277-025-06359-1
IF: 3
应用: WB
反应种属: Human
发表时间: 2025 Apr
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Taurochenodeoxycholic acid suppresses the progression of glioblastoma via HMGCS1/HMGCR/GPX4 signaling pathway in vitro and in vivo
期刊: Cancer Cell International
DOI: 10.1186/s12935-025-03782-2
IF: 5.3
应用: WB
反应种属: Mouse
发表时间: 2025 Apr
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Cepharantine prevents hypertrophic scarring by regulating the TGF-β/SMAD pathway
期刊: Archives Of Dermatological Research
DOI: 10.1007/s00403-025-04120-2
IF: 1.8
应用: WB
反应种属: Mouse
发表时间: 2025 Apr
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Aerobic exercise prevents and improves cognitive dysfunction caused by morphine withdrawal via regulating endogenous opioid peptides in the brain
期刊: Psychopharmacology
DOI:
IF: 3.5
应用: WB
反应种属: Mouse
发表时间: 2024 Oct
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Discovery of LC-MI-3: A Potent and Orally Bioavailable Degrader of Interleukin-1 Receptor-Associated Kinase 4 for the Treatment of Inflammatory Diseases
期刊: Journal Of Medicinal Chemistry
DOI:
IF: 7.3
应用: WB
反应种属: Mouse
发表时间: 2024 May
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Bone-derived PDGF-BB enhances hippocampal non-specific transcytosis through microglia-endothelial crosstalk in HFD-induced metabolic syndrome
期刊: Journal Of Neuroinflammation
DOI:
IF: 9.3
应用: WB
反应种属: Human,Mouse
发表时间: 2024 May
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Oncogenic functions and therapeutic potentials of targeted inhibition of SMARCAL1 in small cell lung cancer
期刊: Cancer Letters
DOI:
IF: 9.7
应用: WB
反应种属: Human
发表时间: 2024 May
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Structure-Activity Relationship Study of New Carbazole Sulfonamide Derivatives as Anticancer Agents with Dual-target Mechanism
期刊: European Journal Of Medicinal Chemistry
DOI: 10.1016/j.ejmech.2024.116509
IF: 6
应用: WB
反应种属: Human
发表时间: 2024 May
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GCN2-eIF2α signaling pathway negatively regulates the growth of triploid crucian carp
期刊: Genomics
DOI: 10.1016/j.ygeno.2024.110832
IF: 3.4
应用: WB
反应种属: Fish
发表时间: 2024 Mar
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IKIP downregulates THBS1/FAK signaling to suppress migration and invasion by glioblastoma cells
期刊: Oncology Research
DOI:
IF: 2
应用: WB
反应种属: Human
发表时间: 2024 Jul
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NUAK1 activates STAT5/GLI1/SOX2 signaling to enhance cancer cell expansion and drives chemoresistance in gastric cancer
期刊: Cell Reports
DOI: 10.1016/j.celrep.2024.114446
IF: 7.5
应用: WB
反应种属: Mouse
发表时间: 2024 Jul
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Apigenin improves testosterone synthesis by regulating endoplasmic reticulum stress
期刊: Biomedicine & Pharmacotherapy
DOI: 10.1016/j.biopha.2024.117075
IF: 6.9
应用: WB
反应种属: Mouse
发表时间: 2024 Jul
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Tryptanthrin promotes pressure ulcers healing in mice by inhibiting macrophage-mediated inflammation via cGAS/STING pathways
期刊: International Immunopharmacology
DOI:
IF: 5.6
应用: WB
反应种属: Mouse
发表时间: 2024 Feb
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Tenacissoside H repressed the progression of glioblastoma by inhibiting the PI3K/Akt/mTOR signaling pathway
期刊: European Journal Of Pharmacology
DOI:
IF: 5
应用: WB
反应种属: Mouse
发表时间: 2024 Feb
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Fatty Acid Oxidation‐Glycolysis Metabolic Transition Affects ECM Homeostasis in Silica‐Induced Pulmonary Fibrosis
期刊: Advanced Science
DOI:
IF: 14.3
应用: WB
反应种属: Mouse
发表时间: 2024 Dec
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Pyroptosis-related gene GSDMC indicates poor prognosis and promotes tumor progression by activating the AKT/mTOR pathway in lung squamous cell carcinoma
期刊: Molecular Carcinogenesis
DOI: 10.1002/mc.23805
IF: 3
应用: WB
反应种属: Mouse
发表时间: 2024 Aug
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Sophocarpine inhibits the progression of glioblastoma via PTEN/PI3K/Akt signaling pathway
期刊: American Journal Of Cancer Research
DOI: 10.62347/SQJB1901
IF: 3.6
应用: WB
反应种属: Human
发表时间: 2024 Aug
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Gallic Acid Can Promote Low-Density Lipoprotein Uptake in HepG2 Cells via Increasing Low-Density Lipoprotein Receptor Accumulation
期刊: Molecules
DOI: 10.3390/molecules29091999
IF: 4.2
应用: WB
反应种属: Human
发表时间: 2024 Apr
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Salmonella Enteritidis T1SS protein SiiD inhibits NLRP3 inflammasome activation via repressing the mtROS-ASC dependent pathway
期刊: PLoS Pathogens
DOI:
IF: 7.464
应用: WB
反应种属: Mouse
发表时间: 2023 May
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Sirt3 improves monosodium urate crystal-induced inflammation by suppressing Acod1 expression
期刊: Arthritis Research & Therapy
DOI: 10.1186/s13075-023-03107-6
IF: 4.9
应用: WB
反应种属: Mouse
发表时间: 2023 Jul
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Boosting ferroptosis and microtubule inhibition for antitumor therapy via a carrier-free supermolecule nanoreactor
期刊: Journal Of Pharmaceutical Analysis
DOI:
IF: 14.026
应用: IF-tissue
反应种属: Mouse
发表时间: 2023 Jan
-
Rab31 promotes metastasis and cisplatin resistance in stomach adenocarcinoma through Twist1-mediated EMT
期刊: Cell Death & Disease
DOI:
IF: 9.685
应用: WB
反应种属: Human
发表时间: 2023 Feb
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Daurisoline suppresses esophageal squamous cell carcinoma growth in vitro and in vivo by targeting MEK1/2 kinase
期刊: Molecular Carcinogenesis
DOI:
IF:
应用:
反应种属:
发表时间: 2023 Apr
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Dynamin-Related Protein 1 Is Involved in Mitochondrial Damage, Defective Mitophagy, and NLRP3 Inflammasome Activation Induced by MSU Crystals
期刊: Oxidative Medicine And Cellular Longevity
DOI:
IF: 7.310
应用: WB
反应种属: Mouse
发表时间: 2022 Oct
-
Toward a Treatment of Cancer: Design and In Vitro/In Vivo Evaluation of Uncharged Pyrazoline Derivatives as a Series of Novel SHP2 Inhibitors
期刊: International Journal Of Molecular Sciences
DOI:
IF: 5.924
应用: WB
反应种属: Human
发表时间: 2022 Mar
-
Porcine Circovirus Type 2 Hijacks Host IPO5 to Sustain the Intracytoplasmic Stability of Its Capsid Protein
期刊: Journal Of Virology
DOI:
IF: 6.549
应用: WB
反应种属: Pig
发表时间: 2022 Dec
-
Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells
期刊: Molecular Cancer Research
DOI:
IF: 5.85
应用: WB,IHC-P
反应种属: Human
发表时间: 2021 Oct
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Marine Bromophenol Bis(2,3,6-Tribromo-4,5-Dihydroxybenzyl)ether Inhibits Angiogenesis in Human Umbilical Vein Endothelial Cells and Reduces Vasculogenic Mimicry in Human Lung Cancer A549 Cells
期刊: Marine Drugs
DOI:
IF: 5.11
应用: WB
反应种属: Human
发表时间: 2021 Nov
-
CDK9 Inhibitor Induces the Apoptosis of B-Cell Acute Lymphocytic Leukemia by Inhibiting c-Myc-Mediated Glycolytic Metabolism
期刊: Frontiers In Cell And Developmental Biology
DOI: 10.3389/fcell.2021.641271
IF: 6.684
应用: WB
反应种属: Human
发表时间: 2021 Mar
-
PNSA, a Novel C-Terminal Inhibitor of HSP90, Reverses Epithelial–Mesenchymal Transition and Suppresses Metastasis of Breast Cancer Cells In Vitro
期刊: Marine Drugs
DOI:
IF: 5.12
应用: WB
反应种属: Human
发表时间: 2021 Feb
-
CDK7 Inhibitor THZ1 Induces the Cell Apoptosis of B-Cell Acute Lymphocytic Leukemia by Perturbing Cellular Metabolism
期刊: Frontiers In Oncology
DOI: 10.3389/fonc.2021.663360
IF: 6.244
应用: WB
反应种属: Human
发表时间: 2021 Apr
-
Iron Oxide Nanoparticles as Autophagy Intervention Agents Suppress Hepatoma Growth by Enhancing Tumoricidal Autophagy
期刊: Advanced Science
DOI:
IF: 15.84
应用: WB
反应种属: Human
发表时间: 2020 Jun
-
ANKRD22, a novel tumor microenvironment-induced mitochondrial protein promotes metabolic reprogramming of colorectal cancer cells
期刊: Theranostics
DOI:
IF: 8.06
应用: WB
反应种属: Human
发表时间: 2020 Jan
-
SUV39H1 is a New Client Protein of Hsp90 Degradated by Chaetocin as a Novel C-Terminal Inhibitor of Hsp90
期刊: Biomolecules & Therapeutics
DOI:
IF: 3.47
应用: WB
反应种属: Human
发表时间: 2020 Jan
-
Discovery of novel 2-aryl-3-sulfonamido-pyridines (HoAns) as microtubule polymerization inhibitors with potent antitumor activities
期刊: European Journal Of Medicinal Chemistry
DOI: 10.1016/j.ejmech.2020.113117
IF: 5.573
应用: WB,IF
反应种属: Human
发表时间: 2020 Dec
-
Antidepressant activity of crocin-I is associated with amelioration of neuroinflammation and attenuates oxidative damage induced by corticosterone in mice.
期刊: Physiology & Behavior
DOI:
IF: 2.64
应用: WB
反应种属: Mouse
发表时间: 2019 Dec
-
Structural basis for the interaction of diapause hormone with its receptor in the silkworm, Bombyx mori
期刊: FASEB Journal
DOI:
IF: 4.8
应用: WB
反应种属: Spodoptera frugiperda
发表时间: 2018 Mar
-
Chronic N-acetylcysteine treatment alleviates acute lipopolysaccharide-induced working memory deficit through upregulating caveolin-1 and synaptophysin in mice
期刊: Psychopharmacology
DOI: 10.1007/s00213-017-4762-y
IF: 3.308
应用: WB
反应种属: Mouse
发表时间: 2017 Oct
-
The profiles of gamma-H2AX along with ATM/DNA-PKcs activation in the lymphocytes and granulocytes of rat and human blood exposed to gamma rays
期刊: Radiation And Environmental Biophysics
DOI: 10.1007/s00411-016-0653-6
IF: 1.923
应用: WB
反应种属: Human,Rat
发表时间: 2016 Jun
-
MicroRNA-223 Enhances Radiation Sensitivity of U87MG Cells In Vitro and In Vivo by Targeting Ataxia Telangiectasia Mutated
期刊: International Journal Of Radiation Oncology, Biology, And Physics
DOI:
IF: 5.133
应用: WB
反应种属: Human
发表时间: 2014 Mar
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Application: WB,IF-Cell,FC,IHC-P
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Application: WB,IHC-P
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beta Tubulin Recombinant Mouse Monoclonal Antibody [1-B11-R]
Application: WB,IF-Cell,IHC-P
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
beta Tubulin Mouse Monoclonal Antibody [1-B11]
Application: WB,IF-Cell,IHC-P,FC,IF-Tissue
Reactivity: Human,Mouse,Rat,Zebrafish
Conjugate: unconjugated
beta Tubulin Recombinant Rabbit Monoclonal Antibody [SR25-04] - BSA and Azide free
Application: WB,IF-Cell,IHC-P,FC
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
iFluor™ 594 Conjugated beta Tubulin Recombinant Mouse Monoclonal Antibody [A1-A4-R]
Application: IF-Cell,IF-Tissue,FC
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Conjugate: iFluor™ 594
beta Tubulin Recombinant Mouse Monoclonal Antibody [1-B11-R] - BSA and Azide free
Application: WB,IF-Cell,IHC-P
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
HRP Conjugated beta Tubulin Recombinant Rabbit Monoclonal Antibody [JF41-50]
Application: WB
Reactivity: Human,Mouse,Rat
Conjugate: HRP
beta Tubulin Recombinant Mouse Monoclonal Antibody [A1-A4-R]
Application: WB,IF-Cell,FC,IHC-P
Reactivity: Human,Mouse,Rat,Monkey
Conjugate: unconjugated

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