HRP Conjugated Human FABP4 Recombinant Rabbit Monoclonal Antibody [PSH25-38] - Detector

功能

Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.

背景文献

1. Ohguro H., Watanabe M., Hikage F., Sato T., Nishikiori N., Umetsu A., Higashide M., Ogawa T., Furuhashi M. Fatty Acid-Binding Protein 4-Mediated Regulation Is Pivotally Involved in Retinal Pathophysiology: A Review. Int J Mol Sci 25:7717-7717 (2024).

2. Xu S., Luo J., Wang Y., Chen X. Fatty Acid Binding Protein-4 Silencing Inhibits Ferroptosis to Alleviate Lipopolysaccharide-induced Injury of Renal Tubular Epithelial Cells by Blocking Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Signaling. J Physiol Investig 67:47-56 (2024).

亚细胞定位

Cytoplasm. Nucleus.

UNIPROT

SwissProt: P15090 Human

别名

Adipocyte lipid-binding protein antibody

Adipocyte-type fatty acid-binding protein antibody

Fatty acid-binding protein 4 antibody

ALBP antibody

A-FABP antibody

AFABP antibody

FABP4 antibody