VEGF Receptor 1 Rabbit Polyclonal Antibody
Catalog# RT1651
VEGF Receptor 1 Rabbit Polyclonal Antibody
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WB
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IP
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IF
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IHC-P
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Human
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Mouse
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Rat
概述
产品名称
VEGF Receptor 1 Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
Recombinant protein within
种属反应性
Human, Mouse, Rat
验证应用
WB, IP, IF, IHC-P
分子量
180 kDa
阳性对照
Human fallopian tube tissue
偶联
unconjugated
产品特性
形态
Liquid
浓度
1ug/ul
存放说明
Store at +4℃
存储缓冲液
1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
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WB
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1:1,000
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IP
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1-2 μg per 100-500 μg of total protein
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IF
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1:50-500
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IHC-P
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1:50-500
靶点
功能
Three cell membrane receptor tyrosine kinases, Flt (also designated VEGF-R1),Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulinlike sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors, including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.
背景文献
1. Mehnert, J.M., et al. 2010. Quantitative expression of VEGF, VEGF-R1,VEGF-R2, and VEGF-R3 in melanoma tissue microarrays. Hum. Pathol. 41:375-384.
2. Andersson, M.K., et al. 2010. Nuclear expression of FLT1 and its ligand PGF in FUS-DDIT3 carrying myxoid liposarcomas suggests the existence of an intracrine signaling loop. BMC Cancer 10: 249.
亚细胞定位
Cell membrane, Cytoplasm, Endosome, Membrane, Secreted.
UNIPROT
别名
EC 2.7.10.1 antibody
FLT 1 antibody
FLT antibody
Flt-1 antibody
FLT1 antibody
Fms like tyrosine kinase 1 antibody
Fms related tyrosine kinase 1 antibody
Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antibody
Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor antibody
Fms-like tyrosine kinase 1 antibody
展开图片
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Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing membrane and cytoplasmic staining of glandular cells.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
VEGF Receptor 1 Recombinant Rabbit Monoclonal Antibody [SY09-09]
Application: WB,IF-Cell,IF-Tissue,IHC-P,IP,FC
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
同靶点 & 同通路的产品
VEGF Receptor 1 Rabbit Polyclonal Antibody
Application: WB,IHC-P
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated