IL-6 Mouse Monoclonal Antibody [3-A4]

功能

Interleukin 6 (IL-6) is a potent pleiotropic cytokine that regulates cell growth and differentiation of various tissues, and is known particularly for its role in the immune response and acute phase reactions. IL-6 is a cytokine with a wide variety of biological functions and belongs to the?IL-6 superfamily. IL-6 is a potent inducer of the acute phase response and plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. This antibody can recognize mouse interleukin 6, which is a matched antibody-pair with product cat # M1303-1.

背景文献

1. "The murine Il-6 gene maps to the proximal region of chromosome 5."Mock B.A., Nordan R.P., Justice M.J., Kozak C., Jenkins N.A., Copeland N.G., Clark S.C., Wong G.G., Rudikoff S.J. Immunol. 142:1372-1376(1989)

2. "Genomic structure of the murine IL-6 gene. High degree conservation of potential regulatory sequences between mouse and human."Tanabe O., Akira S., Kamiya T., Wong G.G., Hirano T., Kishimoto T.J. Immunol. 141:3875-3881(1988)

序列相似性

Belongs to the IL-6 superfamily.

亚细胞定位

Secreted.

UNIPROT

SwissProt: P08505 Mouse

别名