HLA-DQA1 Recombinant Rabbit Monoclonal Antibody
Catalog# IRS062
HLA-DQA1 Recombinant Rabbit Monoclonal Antibody
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mIHC
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Mouse
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unconjugated
概述
产品名称
HLA-DQA1 Recombinant Rabbit Monoclonal Antibody
抗体类型
Recombinant Rabbit monoclonal Antibody
免疫原
Synthetic peptide within Human HLA-DQA1 aa 205-254 / 254.
种属反应性
Mouse
验证应用
mIHC
分子量
Predicted band size: 28 kDa
阳性对照
Mouse spleen tissue, mouse osteosarcoma tissue.
偶联
unconjugated
产品特性
形态
Liquid
浓度
存放说明
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
存储缓冲液
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG
纯化方式
Protein A affinity purified.
应用稀释度
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mIHC
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1:100
靶点
功能
Major histocompatibility complex, class II, DQ alpha 1, also known as HLA-DQA1, is a human gene present on short arm of chromosome 6 (6p21.3) and also denotes the genetic locus which contains this gene. The protein encoded by this gene is one of two proteins that are required to form the DQ heterodimer, a cell surface receptor essential to the function of the immune system.HLA-DQA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen-presenting cells.
背景文献
1. Schmidt H et al. HLA-DR15 haplotype and multiple sclerosis: a HuGE review. Am. J. Epidemiol 165 (10): 1097-109 (2007).
2. Han R et al. Analysis of the nucleotide sequence variation of the antigen-binding domain of DR alpha and DQ alpha molecules as related to the evolution of papillomavirus-induced warts in rabbits. J Invest Dermatol 103(3):376-80 (1994).
序列相似性
Belongs to the MHC class II family.
亚细胞定位
Cell membrane. Endoplasmic reticulum membrane.
UNIPROT
别名
CD antibody
CELIAC1 antibody
DC 1 alpha chain antibody
DC alpha antibody
DC-1 alpha chain antibody
DC-alpha antibody
DC1, included antibody
DQ alpha 1 chain antibody
DQ-A1 antibody
DQ-DRW9 alpha chain antibody
展开图片
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mIHC analysis of mouse spleen tissue (Formalin/PFA-fixed paraffin-embedded sections) with PD-L1 (IRS059), HLA-DR (IRS062), Ly6G and aSMA (IRS048) antibody at 1/100 dilution. The immunostaining was performed with the IRISKitCmTSA Kit (900802). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.
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mIHC analysis of mouse osteosarcoma tissue (Formalin/PFA-fixed paraffin-embedded sections) with Rabbit anti-HLA-DQA1 antibody (IRS062) at 1/100 dilution. The immunostaining was performed with the IRISKitCmTSA Kit (900808). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.
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mIHC analysis of mouse osteosarcoma subcutaneous tumor tissue (Formalin/PFA-fixed paraffin-embedded sections) with Rabbit anti-HLA-DQA1 antibody (IRS062) at 1/100 dilution. The immunostaining was performed with the IRISKitCmTSA Kit (900808). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.
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mIHC analysis of mouse spleen tissue (Formalin/PFA-fixed paraffin-embedded sections) with Rabbit anti-HLA-DQA1 antibody (IRS062) at 1/100 dilution. The immunostaining was performed with the IRISKitCmTSA Kit (900808). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
同靶点 & 同通路的产品
HLA-DQA1 Recombinant Rabbit Monoclonal Antibody [JU17-34]
Application: WB,IHC-P,IP,IF-Cell,mIHC,IF-Tissue,FC
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
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