Biotin Conjugated Human IL-15 Recombinant Rabbit Monoclonal Antibody [PSH04-20]
概述
产品名称
Biotin Conjugated Human IL-15 Recombinant Rabbit Monoclonal Antibody [PSH04-20]
抗体类型
Recombinant Rabbit monoclonal Antibody
免疫原
Recombinant protein within Human IL-15 aa 49-162 (P40933).
种属反应性
Human
验证应用
ELISA(Det)
分子量
Predicted band size: 18.1 kDa
阳性对照
Recombinant standard Human IL-15 protein (HA210773).
偶联
Biotin
克隆号
PSH04-20
产品特性
形态
Liquid
存放说明
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
存储缓冲液
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% ProClin300.
亚型
IgG
纯化方式
Protein A affinity purified.
应用稀释度
-
ELISA(Det)
-
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH04-19] to Human IL-15 (Caputure) (HA722102) and recombinant standard Human IL-15 protein (HA210773). The reference range value is 12.3-1000pg/ml.
靶点
功能
Interleukin-15 (IL-15) is a protein that in humans is encoded by the IL15 gene. IL-15 is an inflammatory cytokine with structural similarity to Interleukin-2 (IL-2). Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces the proliferation of natural killer cells, i.e. cells of the innate immune system whose principal role is to kill virally infected cells.
背景文献
1. Zannikou M et al. IL15 modification enables CAR T cells to act as a dual targeting agent against tumor cells and myeloid-derived suppressor cells in GBM. J Immunother Cancer. 2023 Feb
2. Xu Y et al. An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity. Cancer Immunol Res. 2021 Oct
亚细胞定位
Secreted; Nucleus.
UNIPROT
别名
IL 15 antibody
IL-15 antibody
IL15 antibody
IL15_HUMAN antibody
Interleukin 15 antibody
Interleukin-15 antibody
Interleukin15 antibody
MGC9721 antibody
图片
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
同靶点 & 同通路的产品
Human IL-15 Recombinant Rabbit Monoclonal Antibody [PSH04-19] - BSA and Azide free (Capture)
Application: ELISA(Cap)
Reactivity: Human
Conjugate: unconjugated
