Livin Rabbit Polyclonal Antibody
Catalog# ER1912-40
Livin Rabbit Polyclonal Antibody
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WB
-
IHC-P
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IF-Tissue
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Human
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Mouse
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unconjugated
概述
产品名称
Livin Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
KLH conjugated synthetic peptide derived from human Livin 101-200/298
种属反应性
Human, Mouse
验证应用
WB, IHC-P, IF-Tissue
分子量
33 KDa
阳性对照
Isoform 1 and isoform 2 are expressed at very low levels or not detectable in most adult tissues. Detected in adult heart, placenta, lung, lymph node, spleen and ovary, and in several carcinoma cell lines. Isoform 2 is detected in fetal kidney, heart and spleen, and at lower levels in adult brain, skeletal muscle and peripheral blood leukocytes.
偶联
unconjugated
产品特性
形态
Liquid
浓度
存放说明
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
存储缓冲液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
亚型
IgG
纯化方式
Protein A affinity purified.
应用稀释度
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WB
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1:500-2000
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IHC-P
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1:100-500
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IF-tissue
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1:100-500
靶点
功能
Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.
背景文献
暂无
亚细胞定位
Nucleus. Cytoplasm. Nuclear, and in a filamentous pattern throughout the cytoplasm.
UNIPROT
别名
Baculoviral IAP repeat containing 7 antibody
Baculoviral IAP repeat containing protein 7 antibody
Baculoviral IAP repeat-containing protein 7 antibody
BIRC 7 antibody
birc7 antibody
BIRC7_HUMAN antibody
KIAP antibody
Kidney inhibitor of apoptosis protein antibody
Livin antibody
Livin inhibitor of apotosis antibody
展开图片
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Sample:Lymph node (Mouse) Lysate at 40 ug
Primary: Anti-Livin (ER1912-40) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 33 kD
Observed band size: 35 kD
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
Livin Recombinant Rabbit Monoclonal Antibody [PSH12-72]
Application: WB,IHC-P,IP
Reactivity: Human
Conjugate: unconjugated
同靶点 & 同通路的产品
Human Livin Recombinant Rabbit Monoclonal Antibody [PSH12-94] - BSA and Azide free (Capture)
Application: ELISA(Cap)
Reactivity: Human
Conjugate: unconjugated
Livin Recombinant Rabbit Monoclonal Antibody [PSH12-72]
Application: WB,IHC-P,IP
Reactivity: Human
Conjugate: unconjugated
Livin Recombinant Rabbit Monoclonal Antibody [PSH12-72] - BSA and Azide free
Application: WB,IHC-P,IP
Reactivity: Human
Conjugate: unconjugated
Human Livin Recombinant Rabbit Monoclonal Antibody [PSH12-95] - BSA and Azide free (Detector)
Application: ELISA(Det)
Reactivity: Human
Conjugate: unconjugated
Human Livin Recombinant Rabbit Monoclonal Antibody [PSH12-96] - BSA and Azide free (Capture)
Application: ELISA(Cap)
Reactivity: Human
Conjugate: unconjugated
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