KAT3B / p300 Rabbit Polyclonal Antibody
Catalog# ER1908-18
KAT3B / p300 Rabbit Polyclonal Antibody
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WB
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Human
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Mouse
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Rat
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Monkey
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unconjugated
概述
产品名称
KAT3B / p300 Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
Recombinant protein within human KAT3B / p300 aa 51-350.
种属反应性
Human, Mouse, Rat, Monkey
验证应用
WB
分子量
Predicted band size: 264 kDa
阳性对照
293T cell lysate, HeLa cell lysate, LoVo cell lysate, C2C12 cell lysate, PC-12 cell lysate, COS-1 cell lysate.
偶联
unconjugated
产品特性
形态
Liquid
浓度
存放说明
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
存储缓冲液
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
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WB
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1:20,000
靶点
功能
Histone acetyltransferase p300 also known as p300 HAT or E1A-associated protein p300 (where E1A = adenovirus early region 1A) also known as EP300 or p300 is an enzyme that, in humans, is encoded by the EP300 gene. It functions as histone acetyltransferase that regulates transcription of genes via chromatin remodeling by allowing histone proteins to wrap DNA less tightly. This enzyme plays an essential role in regulating cell growth and division, prompting cells to mature and assume specialized functions (differentiate), and preventing the growth of cancerous tumors. The p300 protein appears to be critical for normal development before and after birth.
背景文献
暂无
亚细胞定位
Cytoplasm, Nucleus, Chromosome.
别名
E1A associated protein p300 antibody
E1A binding protein p300 antibody
E1A-associated protein p300 antibody
EP300 antibody
EP300: E1A binding protein p300 antibody
EP300_HUMAN antibody
Histone acetyltransferase p300 antibody
KAT3B antibody
p300 HAT antibody
RSTS2 antibody
图片
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Western blot analysis of KAT3B / p300 on different lysates with Rabbit anti-KAT3B / p300 antibody (ER1908-18) at 1/20,000 dilution.
Lane 1: 293T cell lysate
Lane 2: HeLa cell lysate
Lane 3: LoVo cell lysate
Lane 4: C2C12 cell lysate
Lane 5: PC-12 cell lysate
Lane 6: COS-1 cell lysate
Lysates/proteins at 20 µg/Lane.
Predicted band size: 264 kDa
Observed band size: 300 kDa
Exposure time: 3 minutes; ECL: K1801;
3-8% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (ER1908-18) at 1/20,000 dilution was used in 5% BSA at 4℃ overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1/50,000 dilution was used for 1 hour at room temperature.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
引文
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HDAC2-Mediated METTL3 Delactylation Promotes DNA Damage Repair and Chemotherapy Resistance in Triple-Negative Breast Cancer
期刊: Advanced Science
DOI: 10.1002/advs.202413121
IF: 14.3
应用: WB
反应种属: Human
发表时间: 2025 Feb
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Regulator of G protein signaling 2 is inhibited by hypoxia-inducible factor-1α/E1A binding protein P300 complex upon hypoxia in human preeclampsia
期刊: International Journal Of Biochemistry And Cell Biology
DOI:
IF: 5.652
应用: WB
反应种属: Human
发表时间: 2022 Jun
同靶点 & 同通路的产品
KAT3B / p300 Recombinant Rabbit Monoclonal Antibody [PSH15-30]
Application: WB,IHC-P,IF-Cell,FC,IP
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
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