Smad2/3 (Acetyl K19) Rabbit Polyclonal Antibody
Catalog# ER60061
Smad2/3 (Acetyl K19) Rabbit Polyclonal Antibody
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IHC-P
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WB
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Human
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Mouse
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Rat
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unconjugated
概述
产品名称
Smad2/3 (Acetyl K19) Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
Synthesized peptide derived from human Smad2/3 (Acetyl-Lys19)
种属反应性
Human, Mouse, Rat
验证应用
IHC-P, WB
分子量
60 kDa
阳性对照
Chronic myeloid leukemia cell,Colon adenocarcinoma,Epithelium,Kidney,Pancreas,Place
偶联
unconjugated
产品特性
形态
Liquid
浓度
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
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IHC-P
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1:50-200
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WB
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1:500-1:2000
靶点
功能
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation
背景文献
暂无
别名
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展开图片
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Immunohistochemical analysis of paraffin-embedded human brain tumor. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
同靶点 & 同通路的产品
Smad2/3 Mouse Monoclonal Antibody [4D3]
Application: WB,IP,IF,IHC-P
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
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