Phospho-NLRC4 (S533) Rat Monoclonal Antibody [B7-B7]
Catalog# EM1707-24
Phospho-NLRC4 (S533) Rat Monoclonal Antibody [B7-B7]
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WB
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IF-Cell
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Human
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Mouse
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unconjugated
概述
产品名称
Phospho-NLRC4 (S533) Rat Monoclonal Antibody [B7-B7]
抗体类型
Mouse Monoclonal Antibody
免疫原
Synthesized peptide of mouse phospho-NLRC4(Ser-533) (AA: 525-538) expressed in E. Coli.
种属反应性
Human, Mouse
验证应用
WB, IF-Cell
分子量
117 kDa
阳性对照
NIH/3T3, Hela
偶联
unconjugated
克隆号
B7-B7
产品特性
形态
Liquid
浓度
存放说明
Store at 4℃ short term. Aliquot and store at -20℃ long term. Avoid freeze/thaw cycles.
存储缓冲液
Purified antibody in PBS with 0.05% sodium azide.
亚型
IgG2b
纯化方式
Protein A affinity purified.
应用稀释度
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WB
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1:500-1:2,000
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IF-Cell
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1:200-1:1,000
靶点
功能
NLRC4 is a cytosolic NOD (nucleotide binding and oligomerization domain)-like receptor (NLR) that can trigger inflammasome formation in response to bacterial flagellin, an immunodominant antigen in the intestine.
背景文献
1. Ataide MA et al. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection. PLoS Pathog 10:e1003885 (2014).
2. Park, E. et al. Activation of NLRP3 and AIM2 inflammasomes by Porphyromonas gingivalis infection. Infection and immunity. 82: 112-23 (2014).
亚细胞定位
Cytoplasm. Cytoplasmic filaments. Nucleus
别名
and NACHT-containing protein antibody
CARD 12 antibody
CARD antibody
CARD LRR and NACHT containing protein 1 antibody
CARD LRR and NACHT containing protein antibody
CARD12 antibody
Caspase recruitment domain containing protein 12 antibody
Caspase recruitment domain family member 12 antibody
Caspase recruitment domain-containing protein 12 antibody
CLAN 1 antibody
展开图片
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Western blot analysis of phospho-NLRC4(Ser-533) on NIH/3T3 cells lysates using anti- phospho-NLRC4(Ser-533) antibody at 1/1,000 dilution.
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Immunofluorescence analysis of Hela cells using phospho-NLRC4(Ser-533) rat mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: A-11006)
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
引文
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Glaucocalyxin A Promotes Spinal Cord Repair By Nrf2/HO-1 Pathway Activation to Suppress AIM2 Inflammasome Formation
期刊: Molecular Neurobiology
DOI: 10.1007/s12035-026-05739-6
IF: 4.3
应用: WB
反应种属: Rat
发表时间: 2026 Feb
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NADPH acts as an endogenous P2X7 receptor modulator to gate neuroinflammatory responses of microglia
期刊: Acta Pharmacologica Sinica
DOI: 10.1038/s41401-025-01638-z
IF: 8.4
应用: WB
反应种属: Mouse
发表时间: 2025 Aug
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Cepharantine prevents hypertrophic scarring by regulating the TGF-β/SMAD pathway
期刊: Archives Of Dermatological Research
DOI: 10.1007/s00403-025-04120-2
IF: 1.8
应用: WB
反应种属: Mouse
发表时间: 2025 Apr
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Glucose-driven transformable complex eliminates biofilm and alleviates inflamm-aging for diabetic periodontitis therapy
期刊: Materials Today Bio
DOI:
IF:
应用: WB
反应种属: Rat
发表时间: 2023 May
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