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Human SIRP Gamma/CD172g Protein

Rmb: 3950

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Catalog# HA210082

Human SIRP Gamma/CD172g Protein

Product Information

Product name

Human SIRP Gamma/CD172g Protein

Catalog No.

HA210082

Predicted molecular mass

The protein has a predicted MW of 39.7 kDa. Due to glycosylation, the protein migrates to 45-52 kDa based on Tris-Bis PAGE result.

Protein construction description

Recombinant Human SIRP Gamma/CD172g Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Glu29-Pro360.

Accession

Q9P1W8

Source

HEK293

Purity

> 95% as determined by Tris-Bis PAGE > 95% as determined by HPLC

Endotoxin

Less than 1EU per μg by the LAL method.

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Species

Human

Background

Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.

Usage guide

Storage

-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

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