Gli1 Mouse Monoclonal Antibody [F8-B9]
Catalog# EM1708-22
Gli1 Mouse Monoclonal Antibody [F8-B9]
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IF-Cell
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IHC-P
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FC
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Human
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unconjugated
概述
产品名称
Gli1 Mouse Monoclonal Antibody [F8-B9]
抗体类型
Mouse Monoclonal Antibody
免疫原
Recombinant protein
种属反应性
Human
验证应用
IF-Cell, IHC-P, FC
分子量
118 kDa
阳性对照
Human GLI1 recombinant protein, GLI1-hIgGFc transfected HEK293 cell lysate, Hela, HepG2, human ovarian cancer tissue, human esophageal cancer tissue.
偶联
unconjugated
克隆号
F8-B9
产品特性
形态
Liquid
浓度
存放说明
4℃; -20℃ for long term storage.
存储缓冲液
Purified antibody in PBS with 0.05% sodium azide.
亚型
IgG1
纯化方式
Protein A affinity purified.
应用稀释度
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IF-cell
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1:50-1:200
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IHC-P
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1:50-1:200
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FC
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1:100-1:200
靶点
功能
Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
背景文献
1. Lin Z et al. Inhibition of the CyclinD1 promoter in response to sonic hedgehog signaling pathway transduction is mediated by Gli1. Exp Ther Med 13:307-314 (2017).
2. Li P et al. Nestin Mediates Hedgehog Pathway Tumorigenesis. Cancer Res 76:5573-83 (2016).
亚细胞定位
Cytoplasm. Nucleus.
UNIPROT
别名
Gli 1 antibody
GLI antibody
GLI family zinc finger 1 antibody
GLI Kruppel family member 1 antibody
gli1 antibody
GLI1_HUMAN antibody
Glioma associated oncogene 1 antibody
Glioma associated oncogene homolog 1 (zinc finger protein) antibody
Glioma associated oncogene homolog antibody
Glioma-associated oncogene antibody
展开图片
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ICC staining GLI1 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-GLI1 antibody. Counter stained with hematoxylin.
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Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissue using anti-GLI1 antibody. Counter stained with hematoxylin.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
Gli1 Recombinant Rabbit Monoclonal Antibody [JF09-08]
Application: WB,IHC-P,IF-Cell
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
同靶点 & 同通路的产品
Gli1 Recombinant Rabbit Monoclonal Antibody [JF09-08]
Application: WB,IHC-P,IF-Cell
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
Gli1 Recombinant Rabbit Monoclonal Antibody [JF09-08] - BSA and Azide free
Application: WB,IHC-P,IF-Cell
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
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