CASK Rabbit Polyclonal Antibody
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Catalog# ER1803-62
CASK Rabbit Polyclonal Antibody
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WB
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IF-Cell
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IHC-P
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FC
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Human
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Rat
概述
产品名称
CASK Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
Recombinant protein within human CASK aa 300-500.
种属反应性
Human, Rat
验证应用
WB, IF-Cell, IHC-P, FC
分子量
Predicted band size: 105 kDa
阳性对照
SiHa cell lysate, A549 cell lysate, SiHa, HT-29, rat brain tissue, human appendix tissue, human prostate cancer tissue, human placenta tissue.
偶联
unconjugated
RRID
产品特性
形态
Liquid
浓度
1ug/ul
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
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WB
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1:500-1:1,000
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IF-Cell
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1:50-1:200
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IHC-P
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1:100-1:200
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FC
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1:50-1:100
靶点
功能
Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.
背景文献
暂无
序列相似性
In the N-terminal section; belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.; Belongs to the MAGUK family.
组织特异性
Ubiquitous. Expression is significantly greater in brain relative to kidney, lung, and liver and in fetal brain and kidney relative to lung and liver.
亚细胞定位
Cell membrane, Nucleus, Cytoplasm, Membrane.
别名
CAGH39 antibody
Caki antibody
Calcium/calmodulin dependent serine protein kinase antibody
Calcium/calmodulin dependent serine protein kinase (MAGUK family) antibody
Calcium/calmodulin dependent serine protein kinase membrane associated guanylate kinase antibody
Calcium/calmodulin-dependent serine protein kinase antibody
CAMGUK antibody
CAMGUK protein antibody
CAMGUK, drosophila, homolog of antibody
casK antibody
展开图片
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Western blot analysis of CASK on different cell lysate using anti-CASK antibody at 1/500 dilution.
Positive control:
Lane 1: SiHa cell lysate
Lane 2: A549 cell lysate -
ICC staining CASK in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-CASK antibody. Counter stained with hematoxylin.
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Immunohistochemical analysis of paraffin-embedded human appendix tissue using anti-CASK antibody. Counter stained with hematoxylin.
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Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti-CASK antibody. Counter stained with hematoxylin.
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Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CASK antibody. Counter stained with hematoxylin.
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Flow cytometric analysis of HT-29 cells with CASK antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
CASK Recombinant Mouse Monoclonal Antibody [A1C5-R]
Application: WB,IHC-P
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
同靶点 & 同通路的产品
CASK Mouse Monoclonal Antibody [A1C7]
Application: WB,IHC-P,IF-Cell
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
CASK Mouse Monoclonal Antibody [A1C5]
Application: WB,IHC-P
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated