BMP2 Recombinant Rabbit Monoclonal Antibody [JE10-29]
Catalog# HA722693
BMP2 Recombinant Rabbit Monoclonal Antibody [JE10-29]
-
WB
-
Human
-
Mouse
-
Rat
概述
产品名称
BMP2 Recombinant Rabbit Monoclonal Antibody [JE10-29]
抗体类型
Recombinant Rabbit monoclonal Antibody
免疫原
Recombinant protein within
种属反应性
Human, Mouse, Rat
验证应用
WB
分子量
Predicted band size: 45 kDa
阳性对照
Caco-2 cell lysate, Saos-2 cell lysate, LNCaP cell lysate, HeLa cell lysate, Human lung tissue lysate, Human liver tissue lysate, Mouse spleen tissue lysate, Rat spleen tissue lysate.
偶联
unconjugated
克隆号
JE10-29
产品特性
形态
Liquid
浓度
1ug/ul
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG
纯化方式
Protein A affinity purified.
应用稀释度
-
WB
-
1:1,000
靶点
功能
Bone morphogenetic protein 2 or BMP-2 belongs to the TGF-β superfamily of proteins. BMP-2 like other bone morphogenetic proteins,[6] plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor interaction. It is also involved in cardiac cell differentiation and epithelial to mesenchymal transition. Like many other proteins from the BMP family, BMP-2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2 may be involved in white adipogenesis and may have metabolic effects.
背景文献
1. Yang Z et al. Hydrogel armed with Bmp2 mRNA-enriched exosomes enhances bone regeneration. J Nanobiotechnology. 2023 Apr
2. Li TT et al. BMP2 as a promising anticancer approach: functions and molecular mechanisms. Invest New Drugs. 2022 Dec
亚细胞定位
Secreted.
别名
BDA2 antibody
BMP-2 antibody
BMP-2A antibody
Bmp2 antibody
BMP2_HUMAN antibody
BMP2A antibody
Bone morphogenetic protein 2 antibody
Bone morphogenetic protein 2A antibody
图片
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Western blot analysis of BMP2 on different lysates with Rabbit anti-BMP2 antibody (HA722693) at 1/1,000 dilution.
Lane 1: Caco-2 cell lysate
Lane 2: Saos-2 cell lysate
Lane 3: LNCaP cell lysate
Lane 4: HeLa cell lysate
Lane 5: Human lung tissue lysate
Lane 6: Human liver tissue lysate
Lysates/proteins at 20 µg/Lane.
Predicted band size: 45 kDa
Observed band size: 38 kDa
Exposure time: 1 minute 2 seconds; ECL: K1802;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (HA722693) at 1/1,000 dilution was used in 5% NFDM/TBST at 4℃ overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1/50,000 dilution was used for 1 hour at room temperature. -
Western blot analysis of BMP2 on different lysates with Rabbit anti-BMP2 antibody (HA722693) at 1/1,000 dilution.
Lane 1: Mouse spleen tissue lysate
Lane 2: Rat spleen tissue lysate
Lysates/proteins at 20 µg/Lane.
Predicted band size: 45 kDa
Observed band size: 38 kDa
Exposure time: 3 minutes; ECL: K1802;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (HA722693) at 1/1,000 dilution was used in 5% NFDM/TBST at 4℃ overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1/50,000 dilution was used for 1 hour at room temperature.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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