Cleaved-Caspase-6 p18 (D162) Rabbit Polyclonal Antibody
Catalog# ER60007
Cleaved-Caspase-6 p18 (D162) Rabbit Polyclonal Antibody
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WB
-
IHC-P
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Mouse
-
Rat
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unconjugated
概述
产品名称
Cleaved-Caspase-6 p18 (D162) Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
The antiserum was produced against synthesized peptide derived from mouse Caspase 6. AA range:144-193
种属反应性
Mouse, Rat
验证应用
WB, IHC-P
分子量
28/35 kDa
阳性对照
Highly expressed in lung, liver, kidney, testis, and heart. Lower levels in spleen, skeletal muscle and brain.
偶联
unconjugated
产品特性
形态
Liquid
浓度
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
-
WB
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1:500-1:2000
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IHC-P
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1:100-1:300
靶点
功能
CASP6 encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 6 is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of CASP6 results in multiple transcript variants that encode different isoforms.
背景文献
暂无
亚细胞定位
Cytoplasm
UNIPROT
别名
Apoptotic protease Mch-2 antibody
Apoptotic protease MCH2 antibody
CASP-6 antibody
CASP6 antibody
CASP6_HUMAN antibody
Caspase 6 antibody
Caspase 6 apoptosis related cysteine protease antibody
Caspase 6
apoptosis related cysteine peptidase antibody
Caspase-6 antibody
展开图片
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Western Blot analysis of mouse 3T3 cells using Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody diluted at 1:1000
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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