What is a Recombinant Antibody?
Recombinant antibodies (rAbs) are monoclonal antibodies that are generated using in vitro cloning. Unlike monoclonal antibodies (mAbs) which are produced using traditional hybridoma-based technologies, genes for an antibody's light and heavy chains are inserted into expression vectors, which are then transfected into host cells for expression. Recombinant antibodies do not need hybridomas and animals in the production process. Because of this technology, recombinant antibodies offer key advantages which include superior lot-to-lot consistency, continuous supply, and cruelty-free production.
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