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Thiophosphate ester Recombinant Rabbit Monoclonal Antibody [SD2020]

RMB: 900 特惠 1500

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Catalog# ET1612-11

Thiophosphate ester Recombinant Rabbit Monoclonal Antibody [SD2020]

Application

  • IP

Reactivity

  • Species independent

Conjugation

  • unconjugated

This product has been cited in peer reviewed publications, see list HERE

概述

产品名称

Thiophosphate ester Recombinant Rabbit Monoclonal Antibody [SD2020]

抗体类型

Recombinant Rabbit monoclonal Antibody

免疫原

Thiophosphate ester lined to KLH.

种属反应性

Species independent

验证应用

IP

偶联

unconjugated

克隆号

SD2020

RRID

AB_3070083

产品特性

形态

Liquid

浓度

存放说明

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

存储缓冲液

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

亚型

IgG

纯化方式

Protein A affinity purified.

应用稀释度

  • IP

  • 1:1,000

靶点

功能

A thiophosphate (or phosphorothioate) is a family of compounds and anions with the general chemical formula PS4-xOx3-(x = 0, 1, 2, or 3). The state of protonation is usually not specified. They could be bound to as many as three protons for the neutral H3PS4-xOx species. Two protons correspond to the related monoanions, and one proton for the dianions. The trianions are highly basic and do not exist in appreciable concentrations in solution. Thiophosphates are tetrahedral anions, with the phosphorus at the center of the tetrahedron.

背景文献

1. Leissing F et al. Substrate thiophosphorylation by Arabidopsis mitogen-activated protein kinases. BMC Plant Biol 16:48 (2016).

2. Li YH et al. AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma. Cell Rep 12:599-609 (2015).

图片

  • Advantages of Using rAbs：<br />Increased Reproducibility<br />Because recombinant antibody production involves sequencing the antibody light and heavy chains, recombinant antibody production allows researchers more control over the antigen. <br />Ease of Scalability and Continuous Supply<br />In vitro methods for producing antibodies are amenable to large-scale production, meaning antibody availability is unlikely to become a limiting factor. Recombinant antibodies can be produced in weeks as opposed to months. <br />Animal-Free Tech<br />Once the antibody-producing genes are isolated, high-throughput in vitro manufacture can be implemented. This eliminates the numerous ethical and animal welfare concerns commonly associated with traditional monoclonal antibody production.

    Advantages of Using rAbs：
    Increased Reproducibility
    Because recombinant antibody production involves sequencing the antibody light and heavy chains, recombinant antibody production allows researchers more control over the antigen.
    Ease of Scalability and Continuous Supply
    In vitro methods for producing antibodies are amenable to large-scale production, meaning antibody availability is unlikely to become a limiting factor. Recombinant antibodies can be produced in weeks as opposed to months.
    Animal-Free Tech
    Once the antibody-producing genes are isolated, high-throughput in vitro manufacture can be implemented. This eliminates the numerous ethical and animal welfare concerns commonly associated with traditional monoclonal antibody production.

请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

引文

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