SOX10 Mouse Monoclonal Antibody [1-11]
Catalog# M1311-1
SOX10 Mouse Monoclonal Antibody [1-11]
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WB
-
IHC-P
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Mouse
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unconjugated
概述
产品名称
SOX10 Mouse Monoclonal Antibody [1-11]
抗体类型
Mouse Monoclonal Antibody
免疫原
Recombinant protein within human SOX10 aa 80-310.
种属反应性
Mouse
验证应用
WB, IHC-P
分子量
Predicted band size: 50 kDa
阳性对照
F9, mouse fetal brain
偶联
unconjugated
克隆号
1-11
RRID
产品特性
形态
Liquid
浓度
存放说明
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
存储缓冲液
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG1
纯化方式
Protein A affinity purified.
应用稀释度
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WB
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1:500-1:1000
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IHC-P
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1:50
靶点
功能
Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease
背景文献
1. Pingault V et al. SOX10: 20 years of phenotypic plurality and current understanding of its developmental function. J Med Genet. 2022 Feb
2. Yoon EC et al. TRPS1, GATA3, and SOX10 expression in triple-negative breast carcinoma. Hum Pathol. 2022 Jul
组织特异性
Expressed in oligodendroglia of the spinal tube (at protein level).
亚细胞定位
Nucleus, cytoplasm
UNIPROT
别名
DOM antibody
DOM antibody
Dominant megacolon mouse human homolog of antibody
MGC15649 antibody
PCWH antibody
SOX 10 antibody
SOX10 antibody
SOX10_HUMAN antibody
SRY (sex determining region Y) box 10 antibody
SRY (sex determining region Y) box 10 antibody
展开图片
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Western blot analysis on F9 (1) and mouse fetal brain (2) cell lysates using anti-SOX10 Mouse mAb.
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Immunohistochemical analysis of paraffin-embedded mouse fetal brain (13.5 days) tissue using anti- SOX10 Mouse mAb.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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