Kpm Rabbit Polyclonal Antibody
Catalog# ER63819
Kpm Rabbit Polyclonal Antibody
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IHC-P
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IF-Cell
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Human
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Mouse
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unconjugated
概述
产品名称
Kpm Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
The antiserum was produced against synthesized peptide derived from human LATS2. AA range:541-590
种属反应性
Human, Mouse
验证应用
IHC-P, IF-Cell
阳性对照
Aorta endothelial cell,Myeloid,Testis,
偶联
unconjugated
产品特性
形态
Liquid
浓度
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
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IHC-P
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1:100-1:300
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IF-cell
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1:100-1:500
靶点
功能
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
背景文献
暂无
UNIPROT
别名
FLJ13161 antibody
Kinase phosphorylated during mitosis protein antibody
KPM antibody
Large tumor suppressor homolog 2 antibody
Large tumor suppressor homolog 2 Drosophila antibody
Large tumor suppressor kinase 2 antibody
LATS large tumor suppressor Drosophila homolog 2 antibody
LATS large tumor suppressor homolog 2 antibody
Lats2 antibody
LATS2_HUMAN antibody
展开图片
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Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using LATS2 Antibody. The picture on the right is blocked with the synthesized peptide.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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