Human Beta-2-microglobulin/B2M, C-His Tag Protein

RMB: 599 特惠 1619 1619

产品规格

20μg

50μg

100μg

现在订购，【现货】

点击询价

联系我们

邮箱: sales@huabio.cn

电话: 0571-88062880

查找各地代理商

Catalog# HA210978

Human Beta-2-microglobulin/B2M, C-His Tag Protein

Product Information

Product name

Human Beta-2-microglobulin/B2M, C-His Tag Protein

Catalog No.

HA210978

Predicted molecular mass

13.1 kD

Protein construction description

A DNA sequence encoding the human Beta-2-microglobulin/B2M protein (P61769) (Ile 21-Met119) was expressed with a His tag at the C-terminus.

Accession

P61769

Protein construction

Beta-2-microglobulin/B2M (21-119) His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation. The disease is caused by variants affecting the gene represented in this entry. Apart from the presence of causative mutations, beta-2-microglobulin may adopt the fibrillar configuration of amyloid when its serum levels are persistently high. High beta(2)-microglobulin serum levels result in amyloidosis in patients on long-term hemodialysis. In contrast to patients with dialysis-related amyloidosis, patients with hereditary amyloidosis have normal circulating concentrations of beta2-microglobulin.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

Human Beta-2-microglobulin/B2M, C-His Tag Protein

RMB: 599 特惠 1619 1619

产品规格

联系我们

Product Information

Product name

Catalog No.

Predicted molecular mass

Protein construction description

Accession

Protein construction

Source

Bio Activity

Purity

Endotoxin

Formulation

Species

Background

Usage guide

Shipping

Storage

Reconstitution

同靶点&同通路的产品

Human HGF, Tag Free

Application:

Reactivity: Human

Conjugate:

Human ACE2, C-His Tag (ECD)

Application:

Reactivity: Human

Conjugate:

Human TRAF3, C-His Tag

Application:

Reactivity: Human

Conjugate:

Human cIAP-2/BIRC3, N-Twin Strep, C-His, Flag Tag

Application:

Reactivity: Human

Conjugate:

Human IL-8/CXCL8 Tag Free

Application:

Reactivity: Human

Conjugate:

Human MMP-2/CLG4A, C-His, Flag Tag

Application:

Reactivity: Human

Conjugate:

Human TOPBP1, C-His Tag

Application:

Reactivity: Human

Conjugate:

Human Periostin/OSF-2, C-His, Flag Tag

Application:

Reactivity: Human

Conjugate:

Human MMP-9, C-His, Flag Tag

Application:

Reactivity: Human

Conjugate:

Human CXCL10, C-Flag Tag

Application:

Reactivity: Human

Conjugate:

Human IL-18, Tag Free

Application:

Reactivity: Human

Conjugate:

Human VEGF165, Tag Free

Application:

Reactivity: Human

Conjugate:

Human CCL2/MCP1, Tag Free

Application:

Reactivity: Human

Conjugate:

Human FGF Basic/FGF2, Tag Free

Application:

Reactivity: Human

Conjugate:

Human MMP-3, C-His, Flag Tag