Human Osteoactivin/GPNMB, C-His Tag (ECD)
Catalog# HA210623
Human Osteoactivin/GPNMB, C-His Tag (ECD)
Product Information
Product name
Human Osteoactivin/GPNMB, C-His Tag (ECD)
Catalog No.
HA210623
Predicted molecular mass
53.4 kD
Protein construction description
A DNA sequence encoding the human Osteoactivin/GPNMB protein (Q14956) (Ala 22-Pro 486) was expressed with a His tag at the C-terminus.
Accession
Q14956
Protein construction
Source
HEK293
Bio Activity
Testing in progress.
Purity
>95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU per μg by the LAL method.
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
Species
Human
Background
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Usage guide
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.
Storage
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
Reconstitution
Reconstitute at 250 μg/ml in sterile water.
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