Serotonin transporter Rabbit Polyclonal Antibody
Catalog# ER1916-44
Serotonin transporter Rabbit Polyclonal Antibody
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WB
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ELISA
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IHC-P
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Human
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Mouse
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Rat
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Chicken
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Dog
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Pig
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Cow
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Sheep
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Guinea pig
概述
产品名称
Serotonin transporter Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
KLH conjugated synthetic peptide derived from human 5-HTT 401-500/630
种属反应性
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, Guinea pig
验证应用
WB, ELISA, IHC-P
分子量
70 KDa
阳性对照
Expressed in platelets (at protein level).
偶联
unconjugated
产品特性
形态
Liquid
浓度
1ug/ul
存放说明
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
存储缓冲液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
亚型
IgG
纯化方式
Protein A affinity purified.
应用稀释度
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WB
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1:500-2000
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ELISA
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1:5000-10000
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IHC-P
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1:100-500
发表文章中的应用
发表文章中的种属
靶点
功能
Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
背景文献
暂无
亚细胞定位
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
UNIPROT #
别名
5 HTT antibody
5 HTTLPR antibody
5 hydroxytryptamine (serotonin) transporter antibody
5 hydroxytryptamine transporter antibody
5HT transporter antibody
5HTT antibody
hSERT antibody
HTT antibody
Na+/Cl- dependent serotonin transporter antibody
OCD1 antibody
展开图片
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Sample:
Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti-SLC6A4 (ER1916-44) at 1/500 dilution
Secondary: Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 70 kD
Observed band size: 70 kD -
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (Serotonin transporter) Polyclonal Antibody, Unconjugated (ER1916-44) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining.
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Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (Serotonin transporter) Polyclonal Antibody, Unconjugated (ER1916-44) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
引文
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Estradiol reduced 5-HT reuptake by downregulating the gene expression of Plasma Membrane Monoamine Transporter (PMAT, Slc29a4) through estrogen receptor β and the MAPK/ERK signaling pathway
Author: Gu, Y., Zhang, N., Zhu, S., Lu, S., Jiang, H., & Zhou, H.
PMID: 35398393
应用: WB
反应种属: Rat
发表时间: 2022 Jun
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Citation
Alternative Products
Serotonin transporter Recombinant Rabbit Monoclonal Antibody [JE34-53]
Application: WB,FC
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
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