TGF beta 1 Mouse Monoclonal Antibody [B2-F6]
Catalog# EM1709-93
TGF beta 1 Mouse Monoclonal Antibody [B2-F6]
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WB
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IHC-P
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FC
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Human
概述
产品名称
TGF beta 1 Mouse Monoclonal Antibody [B2-F6]
抗体类型
Mouse Monoclonal Antibody
免疫原
Recombinant protein within human TGF beta 1 aa 62-195.
种属反应性
Human
验证应用
WB, IHC-P, FC
分子量
44 kDa
阳性对照
Human TGF beta 1 recombinant protein, human lung tissue, human lymphoid tissue, A549.
偶联
unconjugated
克隆号
B2-F6
产品特性
形态
Liquid
浓度
2ug/ul
存放说明
4℃; -20℃ for long term storage.
存储缓冲液
Purified antibody in PBS with 0.05% sodium azide.
亚型
IgG1
纯化方式
Protein A affinity purified.
应用稀释度
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WB
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1:500-1:1,000
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IHC-P
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1:100-1:500
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FC
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1:100-1:200
发表文章中的应用
发表文章中的种属
靶点
功能
The transforming growth factors b (TGFβ) superfamily is composed of numerous growth and differentiation factors, including TGFβ1-3. TGFβs are secreted from cells as latent complexes consisting of mature dimeric growth factor, the latency-associated propeptide (LAP) and a distinct gene product, latent TGFβ binding protein LTBP. Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis. The precursor of TGFβ is cleaved into mature TGFβ and LAP (latency associated peptide). Mature TGFβ remains associated with LAP by non-covalent interactions that block TGFβ from binding to its receptor.
背景文献
暂无
亚细胞定位
Secreted. Extracellular matrix.
UNIPROT #
别名
Cartilage-inducing factor antibody
CED antibody
Differentiation inhibiting factor antibody
DPD1 antibody
LAP antibody
Latency-associated peptide antibody
Prepro transforming growth factor beta 1 antibody
TGF beta 1 antibody
TGF beta antibody
TGF beta 1 protein antibody
展开图片
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Western blot analysis of TGF beta 1 on human TGF beta 1 recombinant protein using anti- TGF beta 1 antibody at 1/1,000 dilution.
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Immunohistochemical analysis of paraffin-embedded human lung tissue using anti- TGF beta 1 antibody. Counter stained with hematoxylin.
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Immunohistochemical analysis of paraffin-embedded human lymphoid tissue using anti- TGF beta 1 antibody. Counter stained with hematoxylin.
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Flow cytometric analysis of A549 cells with TGF beta 1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
引文
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Inhibition of keloid fibroblast proliferation by artesunate is mediated by targeting the IRE1α/XBP1 signaling pathway and decreasing TGF-β1
Author: Han Xiaomei,et al
PMID: 38492983
应用: WB,IHC
反应种属: Human
发表时间: 2024 Mar
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Citation
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DP7-C/mir-26a system promotes bone regeneration by remodeling the osteogenic immune microenvironment
Author: Huang Jie,et al
PMID: 38501171
应用: WB
反应种属: Rat
发表时间: 2024 Mar
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Citation
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Monocyte-derived immature dendritic cells negatively regulate hepatic stellate cells in vitro by secreting IL-10
Author:
PMID: 36608595
应用: WB
反应种属: Human
发表时间: 2023 Mar
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Citation
Alternative Products
TGF beta 1 Recombinant Rabbit Monoclonal Antibody [PD00-17]
Application: WB,IHC-P,IF-Tissue
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
同靶点&同通路的产品
TGF beta 1 Rabbit Polyclonal Antibody
Application: WB
Reactivity: Human
Conjugate: unconjugated