Iba1 Rabbit Polyclonal Antibody
Catalog# ER1802-20
Iba1 Rabbit Polyclonal Antibody
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IHC-P
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Human
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Mouse
概述
产品名称
Iba1 Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
Synthetic peptide within C-terminal human Iba1.
种属反应性
Human, Mouse
验证应用
IHC-P
分子量
17/10/15 kDa
阳性对照
Human tonsil tissue, human spleen tissue, mouse spleen tissue.
偶联
unconjugated
RRID
产品特性
形态
Liquid
浓度
1ug/ul
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
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IHC-P
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1:50-1:200
靶点
功能
Ionized calcium-binding adapter molecule 1 (Iba1), also known as allograft inflammatory factor-1 (AIF-1), is a 147 amino acid cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. Iba1, containing two EF domains, is induced by cytokines and interferons. In an unstimulated state, Iba1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding Iba1 maps to chromosome 6p21.33 and resides in the tumor necrosis factor (TNF) cluster of genes located in the region represented by the human major histocompatibility complex (MHC).
背景文献
暂无
组织特异性
Detected in T-lymphocytes and peripheral blood mononuclear cells.
翻译后修饰
Phosphorylated on serine residues.
亚细胞定位
Plasma membrane. Cytoskeleton.
别名
AIF 1 antibody
AIF-1 antibody
Aif1 antibody
AIF1 protein antibody
AIF1_HUMAN antibody
Allograft inflammatory factor 1 antibody
Allograft inflammatory factor 1 splice variant G antibody
allograft inflammatory factor-1 splice variant Hara-1 antibody
balloon angioplasty responsive transcription antibody
BART 1 antibody
展开图片
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Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Iba1 antibody. Counter stained with hematoxylin.
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Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Iba1 antibody. Counter stained with hematoxylin.
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Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-Iba1 antibody. Counter stained with hematoxylin.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
Iba1 Recombinant Rabbit Monoclonal Antibody [JM36-62]
Application: WB,IHC-P,FC,IP,IF-Cell,IF-Tissue,IHC-Fr,mIHC
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
同靶点&同通路的产品
Iba1 Recombinant Rabbit Monoclonal Antibody [JM36-62]
Application: WB,IHC-P,FC,IP,IF-Cell,IF-Tissue,IHC-Fr,mIHC
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
Iba1 Recombinant Mouse Monoclonal Antibody [8G8]
Application: WB,IHC-P,FC,IP,IHC-Fr
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
