Epigenetics and Nuclear Signaling - ChIP Assays
染色质免疫共沉淀实验(Chromatin Immunoprecipitation, ChIP)通过免疫学方法沉淀蛋白质-DNA复合物,特异性地富集目的蛋白结合的DNA片段。通过对目的片断的纯化与检测,从而获得蛋白质与DNA相互作用的信息。ChIP检测验证是评定一些表观修饰抗体的必要标准。
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