MUC2 Recombinant Rabbit Monoclonal Antibody
Catalog# IRS175RB
MUC2 Recombinant Rabbit Monoclonal Antibody
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mIHC
-
Human
概述
产品名称
MUC2 Recombinant Rabbit Monoclonal Antibody
抗体类型
Recombinant Rabbit monoclonal Antibody
免疫原
Synthetic peptide within Human MUC2 aa 5100-5149 / 5179.
种属反应性
Human
验证应用
mIHC
分子量
Predicted band size: 551 kDa
阳性对照
Human colon tissue.
偶联
unconjugated
产品特性
形态
Liquid
存放说明
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
存储缓冲液
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG
纯化方式
Protein A affinity purified.
应用稀释度
-
mIHC
-
1:100
靶点
功能
The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major com-ponent of various mucus gels and is broadly expressed in normal and tumor cells.
背景文献
1. Xiong J et al. Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice. Sci Rep 6:34079 (2016).
2. Hensel KO et al. Differential expression of mucosal trefoil factors and mucins in pediatric inflammatory bowel diseases. Sci Rep 4:7343 (2014).
亚细胞定位
Secreted.
UNIPROT
别名
Intestinal mucin 2 antibody
Intestinal mucin-2 antibody
MLP antibody
MUC 2 antibody
MUC-2 antibody
Muc2 antibody
MUC2_HUMAN antibody
Mucin 2 antibody
Mucin 2 intestinal antibody
Mucin 2 intestinal/tracheal antibody
展开图片
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mIHC analysis of human colon tissue (Formalin/PFA-fixed paraffin-embedded sections) with Rabbit anti-MUC2 antibody (IRS175RB) at 1/100 dilution. The immunostaining was performed with the IRISKitCmTSA Kit (900808). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
同靶点 & 同通路的产品
MUC2 Recombinant Rabbit Monoclonal Antibody [JA10-92] - BSA and Azide free
Application: WB,IF-Cell,IF-Tissue,IHC-P
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
