IL-13 Receptor alpha 1 Rabbit Polyclonal Antibody
Catalog# 0902-4
IL-13 Receptor alpha 1 Rabbit Polyclonal Antibody
-
WB
-
Human
-
Mouse
概述
产品名称
IL-13 Receptor alpha 1 Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
Synthetic peptide within Human IL13Ra1 aa 102-151 / 427.
种属反应性
Human, Mouse
验证应用
WB
分子量
Predicted band size: 49kDa
阳性对照
D3, HepG2, Hela
偶联
unconjugated
RRID
产品特性
形态
Liquid
浓度
1ug/ul
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
-
WB
-
1:500-1:1,000
发表文章中的应用
| WB | 查看 1 篇文献如下 |
发表文章中的种属
| BHK-21 cells | 查看 1 篇文献如下 |
靶点
功能
Interleukin 13 receptor, alpha 1 encoded by gene Il13ra1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. Together with IL4R-alpha it can form a functional receptor for IL13. IL13Ra1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for IL4 signaling.
背景文献
1. "Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor."Hilton D.J., Zhang J.-G., Metcalf D., Alexander W.S., Nicola N.A., Willson T.A.Proc. Natl. Acad. Sci. U.S.A. 93:497-501(1996)
2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004)
序列相似性
Belongs to the type I cytokine receptor family. Type 5 subfamily.
组织特异性
Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.
亚细胞定位
Membrane
UNIPROT
别名
bB128O4.2.1 (interleukin 13 receptor, alpha 1) antibody
Cancer/testis antigen 19 antibody
CD213a1 antibody
CD213A1 Antigen antibody
CT 19 antibody
CT19 antibody
I13R1_HUMAN antibody
IL 13 receptor subunit alpha 1 antibody
IL 13R alpha 1 antibody
IL 13R subunit alpha 1 antibody
展开图片
-
☑ Knockout (KO)
All lanes: Western blot analysis of IL13RA1 with anti-IL13RA1 antibody (0902-4) at 1:1,000 dilution.
Lane 1: Wild-type Hela whole cell lysate.
Lane 2: IL13RA1 knockout Hela whole cell lysate.
0902-4 was shown to specifically react with IL13RA1 in Wild-type Hela cells. No band was observed when IL13RA1 knockout samples were tested. Wild-type and IL13RA1 knockout samples were subjected to SDS-PAGE. Proteins were transferred to a PVDF membrane and blocked with 5% NFDM in TBST for 1 hour at room temperature. The primary Anti-IL13RA1 antibody (0902-4, 1/1,000) and Anti-HSP90 antibody (ET1605-56, 1/10,000) were used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG H&L (HRP) Secondary Antibody (HA1001) at 1:200,000 dilution was used for 1 hour at room temperature.
Cell lysate was provided by Ubigene Biosciences (Ubigene Biosciences Co., Ltd., Guangzhou, China). -
Western blot analysis on D3 (A) and HepG2 (B) using anti IL13Ra1 polyclonal antibody.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
引文
-
Cellular response to persistent foot-and-mouth disease virus infection is linked to specific types of alterations in the host cell transcriptome
Author: Chao Shen
PMID: 29568077
应用: WB
反应种属: BHK-21 cells
发表时间: 2018 Mar
-
Citation
Alternative Products
IL-13 Receptor alpha 1 Recombinant Rabbit Monoclonal Antibody [JU38-89]
Application: WB,IF-Cell,IHC-P
Reactivity: Human
Conjugate: unconjugated
同靶点 & 同通路的产品