MAP2 Rabbit Polyclonal Antibody
Catalog# IRS071
MAP2 Rabbit Polyclonal Antibody
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mIHC
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Mouse
概述
产品名称
MAP2 Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
Synthetic peptide within human MAP2 aa 1760-1810.
种属反应性
Mouse
验证应用
mIHC
分子量
Predicted band size: 200 kDa
阳性对照
Mouse brain tissue.
偶联
unconjugated
产品特性
形态
Liquid
浓度
1ug/ul
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
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mIHC
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1:100
靶点
功能
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.
背景文献
1. DeGiosio R. et. al. MAP2 immunoreactivity deficit is conserved across the cerebral cortex within individuals with schizophrenia. NPJ Schizophr. 2019 Aug
2. Gumy LF. et. al. MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons. Neuron. 2017 Apr
亚细胞定位
Cytoskeleton, dendrite.
UNIPROT
别名
DKFZp686I2148 antibody
MAP 2 antibody
MAP dendrite specific antibody
MAP-2 antibody
MAP2 antibody
MAP2A antibody
MAP2B antibody
MAP2C antibody
Microtubule associated protein 2 antibody
Microtubule-associated protein 2 antibody
展开图片
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mIHC analysis of mouse brain tissue (Formalin/PFA-fixed paraffin-embedded sections) with Rabbit anti-MAP2 antibody (IRS071) at 1/100 dilution. The immunostaining was performed with the IRISKit® HyperView mTSA Kit (MH900206). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.
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mIHC analysis of mouse brain tissue (Formalin/PFA-fixed paraffin-embedded sections) with PAX6 (IRS066), NeuN, Iba1 (IRS068) and MAP2 (IRS071) antibody at 1/100 dilution. The immunostaining was performed with the IRISKit® HyperView mTSA Kit (MH900206). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 30 mins at 95℃. DAPI (blue) was used as a nuclear counter stain. Image acquisition was performed with Olympus VS200 Slide Scanner.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"