SOCS1 Rabbit Polyclonal Antibody
Catalog# ER64997
SOCS1 Rabbit Polyclonal Antibody
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IF-Cell
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WB
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IHC-P
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Human
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Mouse
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Rat
概述
产品名称
SOCS1 Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
The antiserum was produced against synthesized peptide derived from human SOCS-1. AA range:49-98
种属反应性
Human, Mouse, Rat
验证应用
IF-Cell, WB, IHC-P
分子量
38 kDa
阳性对照
B-cell,Lung,Myeloid leukemia cell,T-cell lymphoma,
偶联
unconjugated
产品特性
形态
Liquid
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
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IF-cell
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1:50-200
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WB
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1:500-1:2000
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IHC-P
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1:50-300
靶点
功能
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
背景文献
暂无
UNIPROT
别名
CIS1 antibody
CISH 1 antibody
CISH1 antibody
Cytokine inducible SH2 protein 1 antibody
JAB antibody
JAK binding protein antibody
JAK-binding protein antibody
Janus kinase binding protein antibody
SOCS 1 antibody
SOCS-1 antibody
展开图片
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Immunofluorescence analysis of mouse-liver tissue. 1,SOCS-1 Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B
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Immunohistochemical analysis of paraffin-embedded Human-uterus tissue. 1,SOCS-1 Polyclonal Antibody was diluted at 1:200(4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min). Negative control was used by secondary antibody only.
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Western Blot analysis of KB cell lysate using SOCS-1 Polyclonal Antibody diluted at 1:2000
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
SOCS1 Recombinant Rabbit Monoclonal Antibody [PSH09-68]
Application: WB
Reactivity: Human,Mouse,Rat,Monkey
Conjugate: unconjugated
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