PCDH9 Mouse Monoclonal Antibody [A2-G3]
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Catalog# EM1707-91
PCDH9 Mouse Monoclonal Antibody [A2-G3]
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WB
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IF-Cell
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FC
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Human
概述
产品名称
PCDH9 Mouse Monoclonal Antibody [A2-G3]
抗体类型
Mouse Monoclonal Antibody
免疫原
Recombinant protein
种属反应性
Human
验证应用
WB, IF-Cell, FC
分子量
136 kDa
阳性对照
Human PCDH9 recombinant protein, PCDH9-hIgGFc transfected HEK293 cell lysate, C6, Hela.
偶联
unconjugated
克隆号
A2-G3
产品特性
形态
Liquid
浓度
2ug/ul
存放说明
4℃; -20℃ for long term storage.
存储缓冲液
Purified antibody in PBS with 0.05% sodium azide.
亚型
IgG1
纯化方式
Protein A affinity purified.
应用稀释度
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WB
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1:500-1:2,000
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IF-cell
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1:50-1:200
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FC
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1:100-1:200
靶点
功能
Potential calcium-dependent cell-adhesion protein.This gene encodes a member of the protocadherin family, and cadherin superfamily, of transmembrane proteins containing cadherin domains. These proteins mediate cell adhesion in neural tissues in the presence of calcium. The encoded protein may be involved in signaling at neuronal synaptic junctions. Sharing a characteristic with other protocadherin genes, this gene has a notably large exon that encodes multiple cadherin domains and a transmembrane region. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
背景文献
1. Chen Y et al. Loss of PCDH9 is associated with the differentiation of tumor cells and metastasis and predicts poor survival in gastric cancer.Clin Exp Metastasis 32(5):417-28 (2015).
2. Wang C et al. Downregulation of PCDH9 predicts prognosis for patients with glioma.J Clin Neurosci 19(4):541-5 (2012).
亚细胞定位
Cell membrane.
UNIPROT
别名
PCDH9 antibody
PCDH9_HUMAN antibody
Protocadherin-9 antibody
图片
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Western blot analysis of PCDH9 on human PCDH9 recombinant protein using anti-PCDH9 antibody at 1/1,000 dilution.
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Western blot analysis of PCDH9 on HEK293 (1) and PCDH9-hIgGFc transfected HEK293 (2) cell lysate using anti-PCDH9 antibody at 1/1,000 dilution.
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Western blot analysis of PCDH9 on C6 cell lysate using anti-PCDH9 antibody at 1/1,000 dilution.
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ICC staining PCDH9 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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Flow cytometric analysis of Hela cells with PCDH9 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"