FSH Mouse Monoclonal Antibody [AH33-72]
Catalog# EM170418
FSH Mouse Monoclonal Antibody [AH33-72]
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ELISA
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WB
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IHC-P
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ICC
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Human
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Mouse
概述
产品名称
FSH Mouse Monoclonal Antibody [AH33-72]
抗体类型
Mouse Monoclonal Antibody
免疫原
recombinant protein
种属反应性
Human, Mouse
验证应用
ELISA, WB, IHC-P, ICC
分子量
15 kDa
阳性对照
D3, HepG2, JAR, mouse placenta tissue.
偶联
unconjugated
克隆号
AH33-72
产品特性
形态
Liquid
浓度
2ug/ul
存放说明
Store at -20 ℃. Stable for 12 months from date of receipt.
存储缓冲液
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.22% Sodium Azide.
亚型
IgG1
纯化方式
Protein G affinity purified.
应用稀释度
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WB
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1:1,000
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IHC-P
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1:50-1:200 ICC: 1:50-1:200
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ELISA
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1:5,000-1:10,000
靶点
功能
Follicle-stimulating hormone (FSH), also called follitropin, belongs to the family of glycoprotein hormones that also includes luteininizing hormone and thyroid-stimulating hormone. These hormones are secreted by the pituitary and exist as heterodimers, consisting of a common α subunit and a homologous but distinct β subunit. While the α subunit of FSH is involved in the binding of FSH to the receptor (follicle-stimulating hormone receptor, also known as FSHR), the β subunit stabilizes this interaction. This heterodimer regulates a variety of processes, including secretion, posttranslational modification and signal transduction. Both FSH and FSHR are localized to Sertoli cells.
背景文献
1. Han, L. et al. 2013. Characterization of the mechanism of inhibin α-subunit gene in mouse anterior pituitary cells by RNA interference. PloS one. 8: e74596.
2. Chilvers, RA. et al. 201
3. Development of a novel protocol for isolation and purification of human granulosa cells. J. Assist. Reprod. Genet.. 29: 547-556.
亚细胞定位
Secreted
UNIPROT
别名
Anterior pituitary glycoprotein hormones common subunit alpha antibody
CG alpha antibody
CG-alpha antibody
cga antibody
Choriogonadotropin alpha chain antibody
Chorionic Gonadotrophin Alpha antibody
Chorionic Gonadotrophin Alpha Subunit antibody
Chorionic gonadotrophin subunit alpha antibody
chorionic gonadotropin
alpha polypeptide antibody
展开图片
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ICC staining FSH in D3 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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ICC staining FSH in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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ICC staining FSH in JAR cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-FSH antibody. Counter stained with hematoxylin.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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