ATG14L Mouse Monoclonal Antibody [C10-F7]
Catalog# EM1708-11
ATG14L Mouse Monoclonal Antibody [C10-F7]
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IHC-P
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Human
概述
产品名称
ATG14L Mouse Monoclonal Antibody [C10-F7]
抗体类型
Mouse Monoclonal Antibody
免疫原
Purified recombinant fragment of human ATG14L (AA: 43-303) expressed in E. Coli.
种属反应性
Human
验证应用
IHC-P
分子量
55 kDa
阳性对照
Human testis tissues.
偶联
unconjugated
克隆号
C10-F7
产品特性
形态
Liquid
浓度
2ug/ul
存放说明
Store at 4℃ short term. Aliquot and store at -20℃ long term. Avoid freeze/thaw cycles.
存储缓冲液
Purified antibody in PBS with 0.05% sodium azide.
亚型
IgG1
纯化方式
Protein A affinity purified.
应用稀释度
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IHC-P
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1:200-1:1,000
靶点
功能
Required for both basal and inducible autophagy. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner.
背景文献
1. Liu J et al. Ad-HGF improves the cardiac remodeling of rat following myocardial infarction by upregulating autophagy and necroptosis and inhibiting apoptosis. Am J Transl Res 8:4605-4627 (2016).
2. Fogel AI et al. Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy.Mol Cell Biol 33(18):3675-88 (2013).
亚细胞定位
Cytoplasm.
UNIPROT
别名
1110038I05Rik antibody
AI314632 antibody
Aldehyde dehydrogenase 6 family member A1 antibody
Aldehyde dehydrogenase family 6 member A1 antibody
Aldehyde dehydrogenase family 6, subfamily A1 antibody
ALDH6A1 antibody
Malonate semialdehyde dehydrogenase antibody
Malonate-semialdehyde dehydrogenase [acylating] antibody
Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial antibody
Methylmalonate-semialdehyde dehydrogenase [acylating] antibody
展开图片
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Immunohistochemical analysis of paraffin-embedded human testis tissues using ATG14L mouse mAb with DAB staining.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Alternative Products
ATG14L Rabbit Polyclonal Antibody
Application: WB,IHC-P
Reactivity: Human,Mouse,Rat
Conjugate: unconjugated
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