Stra8 Rabbit Polyclonal Antibody
Catalog# ER1917-31
Stra8 Rabbit Polyclonal Antibody
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WB
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IHC-P
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IF-Tissue
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Mouse
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Rat
概述
产品名称
Stra8 Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
KLH conjugated synthetic peptide derived from human Stra8 201-300/330
种属反应性
Mouse, Rat
验证应用
WB, IHC-P, IF-Tissue
分子量
45 KDa
阳性对照
Expressed specifically in testis.
偶联
unconjugated
产品特性
形态
Liquid
浓度
1ug/ul
存放说明
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
存储缓冲液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
亚型
IgG
纯化方式
Protein A affinity purified.
应用稀释度
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WB
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1:500-2000
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IHC-P
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1:100-500
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IF-tissue
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1:100-500
发表文章中的应用
| WB | 查看 1 篇文献如下 |
发表文章中的种属
| Mouse | 查看 1 篇文献如下 |
靶点
功能
This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. STRA8 (Stimulated By Retinoic Acid 8) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include protein dimerization activity. Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. Can associate with DNA (possibly in an indirect manner), and in vitro can activate DNA transcription (By similarity).
背景文献
暂无
亚细胞定位
Cytoplasm.
UNIPROT
别名
Stimulated by retinoic acid 8 antibody
stimulated by retinoic acid 8 homolog antibody
Stimulated by retinoic acid Gene 8 antibody
stimulated by retinoic acid gene 8 homolog antibody
Stimulated by retinoic acid gene 8 protein homolog antibody
STRA 8 antibody
STRA8 antibody
STRA8_HUMAN antibody
图片
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Paraformaldehyde-fixed, paraffin embedded (Rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Stra8) Polyclonal Antibody, Unconjugated (ER1917-31) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
引文
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Regulation of spermatogonial stem cell differentiation by Sertoli cells-derived exosomes through paracrine and autocrine signaling
Author: Hairui Tian, Xingju Wang, Xiaoxiao Li, Weixiang Song, Jiaqi Mi, Kang Zou
PMID: 38291718
应用:
反应种属:
发表时间: 2024 Jan
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Citation
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Difenoconazole Exposure Induces Retinoic Acid Signaling Dysregulation and Testicular Injury in Mice Testes
Author: Zheng, X., Wei, Y., Chen, J., Wang, X., Li, D., Yu, C., Hong, Y., Shen, L., Long, C., Wei, G., & Wu, S.
PMID: 37112555
应用: WB
反应种属: Mouse
发表时间: 2023 Mar
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Citation
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