OCT-4 Recombinant Rabbit Monoclonal Antibody
Catalog# RE6048
OCT-4 Recombinant Rabbit Monoclonal Antibody
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WB
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IHC-P
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FC
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IP
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Human
概述
产品名称
OCT-4 Recombinant Rabbit Monoclonal Antibody
抗体类型
Recombinant Rabbit monoclonal Antibody
免疫原
peptide
种属反应性
Human
验证应用
WB, IHC-P, FC, IP
分子量
45kDa
阳性对照
Hela, Seminoma, NCCIT.
偶联
unconjugated
产品特性
形态
Liquid
浓度
1ug/ul
存放说明
Store at -20 ℃. Stable for 12 months from date of receipt
存储缓冲液
1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG
纯化方式
Tissue culture supernatant
应用稀释度
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WB
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1:1,000
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IP
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1:10-100
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IHC-P
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1:100
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FC
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1:10-100
发表文章中的应用
| WB | 查看 1 篇文献如下 |
发表文章中的种属
| Human | 查看 1 篇文献如下 |
靶点
功能
Octamer transcription factor-4 (Oct-4) is a homeodomain transcription factor in the POU transcription factor family that specifically binds to the octamer motif (5'-ATTTCAT-3') (1). It is critical for early embryogenesis and for embryonic stem cell pluripotency, expressed mainly in the developing brain (1). OCT4 is a master regulator that affects the fate of pluripotent stem cells and germ cell precursors (2). For instance, the downregulation of Oct-4 triggers embryonic stem cell differentiation, simultaneous with gastrulation (3). It is also used as a marker for germ cell tumor diagnosis (4).
背景文献
1. The UniProt Consortium, The Universal Protein Resource (UniProt), Nucleic Acids Res. 37:D169-D174(2010).
2. Wei F et al. J Biol Chem. 282(29):21551-60, 2007.
3. Pesce et al. Stem Cells. 19(4):271-8, 2001.
4. Cheng et al. J Pathol. 211(1):1-9, 2007.
亚细胞定位
Cytoplasm, Nucleus
UNIPROT
别名
Octamer binding transcription factor 4 antibody
MGC22487 antibody
Oct 3 antibody
Oct 4 antibody
Oct-3 antibody
Oct-4 antibody
OCT3 antibody
Oct4 antibody
Octamer binding protein 3 antibody
Octamer binding protein 4 antibody
展开图片
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Western blot analysis on (A) Seminoma, (B) NCCIT, and (C) HeLa cell lysates using anti-Oct-4
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Immunohistochemical staining of paraffin-embedded human ovarian dysgerminoma using anti-Oct-4 RabMAb.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
引文
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All-Trans Retinoic Acid-Induced Deficiency of the Wnt/β-Catenin Pathway Enhances Hepatic Carcinoma Stem Cell Differentiation
Author: Meizhang Li
PMID: 26571119
应用: WB
反应种属: Human
发表时间: 2015 Nov
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Citation
Alternative Products
Oct4 Recombinant Rabbit Monoclonal Antibody [SD0750]
Application: WB,IF-Cell,IF-Tissue,IHC-P,IP,FC,ChIP
Reactivity: Human,Mouse
Conjugate: unconjugated
