RGS14 Rabbit Polyclonal Antibody
Catalog# ER64806
RGS14 Rabbit Polyclonal Antibody
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WB
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Human
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Mouse
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Rat
概述
产品名称
RGS14 Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
The antiserum was produced against synthesized peptide derived from human RGS14. AA range:125-174
种属反应性
Human, Mouse, Rat
验证应用
WB
分子量
65 kDa
阳性对照
Brain,Caudate nucleus,Colon,
偶联
unconjugated
产品特性
形态
Liquid
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
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WB
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1:500-1:2000
靶点
功能
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
背景文献
暂无
UNIPROT
别名
Highly similar to rap1/rap2 interacting protein antibody
OTTHUMP00000223586 antibody
OTTHUMP00000223587 antibody
Regulation of G protein signaling 14 antibody
Regulator of G protein signaling 14 antibody
Regulator of G protein signalling 14 antibody
Regulator of G-protein signaling 14 antibody
RGS 14 antibody
RGS14 antibody
RGS14_HUMAN antibody
图片
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Western Blot analysis of 3T3 cells using RGS14 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"