Claudin 8 Rabbit Polyclonal Antibody
Catalog# ER63027
Claudin 8 Rabbit Polyclonal Antibody
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WB
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Human
概述
产品名称
Claudin 8 Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
The antiserum was produced against synthesized peptide derived from human CLDN8. AA range:81-130
种属反应性
Human
验证应用
WB
分子量
28 kDa
阳性对照
Colon,Kidney,
偶联
unconjugated
产品特性
形态
Liquid
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
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WB
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1:500-1:2000
发表文章中的应用
| WB | 查看 1 篇文献如下 |
发表文章中的种属
| Rat | 查看 1 篇文献如下 |
靶点
功能
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.,
背景文献
暂无
UNIPROT
别名
Claudin 8 antibody
Claudin-8 antibody
CLD8_HUMAN antibody
Cldn8 antibody
Epididymis secretory protein Li 79 antibody
HEL S 79 antibody
OTTHUMP00000101915 antibody
图片
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Western blot analysis of lysates from Jurkat cells, using CLDN8 Antibody. The lane on the right is blocked with the synthesized peptide.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
引文
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Rat tight junction proteins are disrupted after subchronic exposure to okadaic acid
Author:
PMID: 36940028
期刊: Environmental Science And Pollution Research
应用: WB
反应种属: Rat
发表时间: 2023 May
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Citation