4E-BP1 Rabbit Polyclonal Antibody
Catalog# ER62532
4E-BP1 Rabbit Polyclonal Antibody
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WB
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IHC-P
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Mouse
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Rat
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Monkey
概述
产品名称
4E-BP1 Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
The antiserum was produced against synthesized peptide derived from mouse 4E-BP1. AA range:35-84
种属反应性
Mouse, Rat, Monkey
验证应用
WB, IHC-P
分子量
12 kDa
偶联
unconjugated
产品特性
形态
Liquid
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
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WB
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1:500-1:2000
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IHC-P
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1:100-1:300
靶点
功能
EIF4EBP1 encodes one member (eukaryotic translation initiation factor 4E binding protein 1) of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
背景文献
暂无
UNIPROT
别名
4E-BP1 antibody
4EBP1 antibody
4EBP1_HUMAN antibody
BP 1 antibody
eIF4E binding protein 1 antibody
eIF4E-binding protein 1 antibody
Eif4ebp1 antibody
Eukaryotic translation initiation factor 4E-binding protein 1 antibody
PHAS-I antibody
PHASI antibody
展开图片
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Western Blot analysis of COS7 cells using 4E-BP1 Polyclonal Antibody diluted at 1:500.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"