GAPDH Recombinant Rabbit Monoclonal Antibody [SA30-01] - Loading control
Catalog# ET1601-4
GAPDH Recombinant Rabbit Monoclonal Antibody [SA30-01] - Loading control
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WB
-
IF-Cell
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IF-Tissue
-
IHC-P
-
FC
-
IP
-
Human
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Mouse
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Rat
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Chicken
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Zebrafish
概述
产品名称
GAPDH Recombinant Rabbit Monoclonal Antibody [SA30-01] - Loading control
抗体类型
Recombinant Rabbit monoclonal Antibody
免疫原
Recombinant protein within mouse GAPDH aa 94-333 / 333.
种属反应性
Human, Mouse, Rat, Chicken, Zebrafish
验证应用
WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
分子量
Predicted band size: 36 kDa
阳性对照
Rat liver tissue lysate, rat lung tissue lysate, rat heart tissue lysate, rat cerebellum tissue lysate, rat skeletal muscle tissue lysate, rat spleen tissue lysate, rat small intestine tissue lysate, hybrid fish (crucian-carp) brain tissue lysates, PC-3 cell lysate, mouse colon tissue lysate, SH-SY5Y cell lysate, NIH/3T3 cell lysate, SK-Br-3 cell lysate, rat brain tissue lysate, A549, HepG2, human liver tissue, mouse liver tissue, mouse spleen tissue, DF-1 cell lysate.
偶联
unconjugated
克隆号
SA30-01
RRID
产品特性
形态
Liquid
浓度
1ug/ul
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型
IgG
纯化方式
Protein A affinity purified.
应用稀释度
-
WB
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1:5,000-1:640,000
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IF-Cell
-
1:50
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IF-Tissue
-
1:50
-
IHC-P
-
1:50
-
FC
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1:50
-
IP
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Use at an assay dependent concentration.
发表文章中的应用
靶点
功能
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
背景文献
1. "High-resolution structure of human D-glyceraldehyde-3-phosphate dehydrogenase."Jenkins J.L., Tanner J.J.Acta Crystallogr. D 62:290-301(2006)
2. "Structural analysis of human liver glyceraldehyde-3-phosphate dehydrogenase."Ismail S.A., Park H.W.Acta Crystallogr. D 61:1508-1513(2005)
序列相似性
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
翻译后修饰
S-nitrosylation of Cys-152 leads to interaction with SIAH1, followed by translocation to the nucleus (By similarity). S-nitrosylation of Cys-247 is induced by interferon-gamma and LDL(ox) implicating the iNOS-S100A8/9 transnitrosylase complex and seems to prevent interaction with phosphorylated RPL13A and to interfere with GAIT complex activity.; ISGylated.; Sulfhydration at Cys-152 increases catalytic activity.; Oxidative stress can promote the formation of high molecular weight disulfide-linked GAPDH aggregates, through a process called nucleocytoplasmic coagulation. Such aggregates can be observed in vivo in the affected tissues of patients with Alzheimer disease or alcoholic liver cirrhosis, or in cell cultures during necrosis. Oxidation at Met-46 may play a pivotal role in the formation of these insoluble structures. This modification has been detected in vitro following treatment with free radical donor (+/-)-(E)-4-ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide. It has been proposed to destabilize nearby residues, increasing the likelihood of secondary oxidative damages, including oxidation of Tyr-45 and Met-105. This cascade of oxidations may augment GAPDH misfolding, leading to intermolecular disulfide cross-linking and aggregation.; Succination of Cys-152 and Cys-247 by the Krebs cycle intermediate fumarate, which leads to S-(2-succinyl)cysteine residues, inhibits glyceraldehyde-3-phosphate dehydrogenase activity. Fumarate concentration as well as succination of cysteine residues in GAPDH is significantly increased in muscle of diabetic mammals. It was proposed that the S-(2-succinyl)cysteine chemical modification may be a useful biomarker of mitochondrial and oxidative stress in diabetes and that succination of GAPDH and other thiol proteins by fumarate may contribute to the metabolic changes underlying the development of diabetes complications.
亚细胞定位
Cytoplasm, Nucleus, Membrane
UNIPROT #
别名
38 kDa BFA-dependent ADP-ribosylation substrate antibody
aging associated gene 9 protein antibody
Aging-associated gene 9 protein antibody
BARS-38 antibody
cb609 antibody
EC 1.2.1.12 antibody
Epididymis secretory sperm binding protein Li 162eP antibody
G3P_HUMAN antibody
G3PD antibody
G3PDH antibody
展开38 kDa BFA-dependent ADP-ribosylation substrate antibody
aging associated gene 9 protein antibody
Aging-associated gene 9 protein antibody
BARS-38 antibody
cb609 antibody
EC 1.2.1.12 antibody
Epididymis secretory sperm binding protein Li 162eP antibody
G3P_HUMAN antibody
G3PD antibody
G3PDH antibody
GAPD antibody
GAPDH antibody
Glyceraldehyde 3 phosphate dehydrogenase antibody
Glyceraldehyde-3-phosphate dehydrogenase antibody
HEL-S-162eP antibody
KNC-NDS6 antibody
MGC102544 antibody
MGC102546 antibody
MGC103190 antibody
MGC103191 antibody
MGC105239 antibody
MGC127711 antibody
MGC88685 antibody
OCAS, p38 component antibody
OCT1 coactivator in S phase, 38-KD component antibody
peptidyl cysteine S nitrosylase GAPDH antibody
Peptidyl-cysteine S-nitrosylase GAPDH antibody
wu:fb33a10 antibody
折叠图片
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Western blot analysis of GAPDH on Hela cell lysates with Rabbit anti-GAPDH antibody (ET1601-4).
Hela cell lysates at 10 µg/Lane.
Predicted band size: 36 kDa
Observed band size: 36 kDa
12% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (ET1601-4) at serial dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:300,000 dilution was used for 1 hour at room temperature. -
Western blot analysis of GAPDH on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (ET1601-4, 1/5,000) was used in 5% NFDM/TBST at room temperature for 1 hour. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:200,000 dilution was used for 45 mins at room temperature.
Positive control:
Lane 1: PC-3 cell lysate, 10 µg/Lane
Lane 2: Mouse colon tissue lysate, 20 µg/Lane
Lane 3: SH-SY5Y cell lysate, 10 µg/Lane
Lane 4: PC-3 cell lysate, 10 µg/Lane
Lane 5: NIH/3T3 cell lysate, 10 µg/Lane
Lane 6: SK-Br-3 cell lysate, 10 µg/Lane
Lane 7: Rat brain tissue lysate, 20 µg/Lane -
Western blot analysis of GAPDH on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (ET1601-4, 1/10,000) was used in 5% NFDM/TBST at room temperature for 1 hour. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:200,000 dilution was used for 45 mins at room temperature.
Positive control:
Lane 1: Rat liver tissue lysate, 20 µg/Lane
Lane 2: Rat lung tissue lysate, 20 µg/Lane
Lane 3: Rat lung tissue lysate, 20 µg/Lane
Lane 4: Rat heart tissue lysate, 20 µg/Lane
Lane 5: Rat cerebellum tissue lysate, 20 µg/Lane
Lane 6: Rat skeletal muscle tissue lysate, 20 µg/Lane
Lane 7: Rat spleen tissue lysate, 20 µg/Lane
Lane 8: Rat small intestine tissue lysate, 20 µg/Lane -
Western blot analysis of GAPDH on different lysates with Rabbit anti-GAPDH antibody (ET1601-4) at 1/80,000 dilution.
Cell lysates at 10 µg/Lane, tissue lysates at 20 µg/Lane.
Predicted band size: 36 kDa
Observed band size: 36 kDa
Exposure time: 1 minute;
12% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (ET1601-4) at 1/80,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:300,000 dilution was used for 1 hour at room temperature. -
Western blot analysis of GAPDH on DF-1 cell lysates with Rabbit anti-GAPDH antibody (ET1601-4) at 1/10,000 dilution.
Cell lysates at 15 µg/Lane.
Predicted band size: 36 kDa
Observed band size: 36 kDa
Exposure time: 1 second;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 2 hour at room temperature. The primary antibody (ET1601-4) at 1/10,000 dilution was used in 5% NFDM/TBST at 4 ℃ overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 2 hour at room temperature. -
ICC staining of GAPDH in A549 cells (green). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with the primary antibody (ET1601-4, 1/50) for 1 hour at room temperature, washed with PBS. Alexa Fluor®488 Goat anti-Rabbit IgG was used as the secondary antibody at 1/1,000 dilution. The nuclear counter stain is DAPI (blue).
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ICC staining of GAPDH in HepG2 cells (green). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with the primary antibody (ET1601-4, 1/50) for 1 hour at room temperature, washed with PBS. Alexa Fluor®488 Goat anti-Rabbit IgG was used as the secondary antibody at 1/1,000 dilution. The nuclear counter stain is DAPI (blue).
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Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-GAPDH antibody. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes.The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (ET1601-4, 1/50) for 30 minutes at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
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Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-GAPDH antibody. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes.The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (ET1601-4, 1/50) for 30 minutes at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
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Flow cytometric analysis of GAPDH was done on HepG2 cells. The cells were fixed, permeabilized and stained with the primary antibody (ET1601-4, 1/50) (blue). After incubation of the primary antibody at room temperature for an hour, the cells were stained with a Alexa Fluor 488-conjugated Goat anti-Rabbit IgG Secondary antibody at 1/1000 dilution for 30 minutes.Unlabelled sample was used as a control (cells without incubation with primary antibody; red).
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Western blot analysis of GAPDH on zebrafish tissue lysates with Rabbit anti-GAPDH antibody (ET1601-4) at 1/5,000 dilution.
Lysates/proteins at 40 µg/Lane.
Predicted band size: 36 kDa
Observed band size: 36 kDa
Exposure time: 14 seconds;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (ET1601-4) at 1/5,000 dilution was used in 5% NFDM/TBST at 4℃ overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1/50,000 dilution was used for 1 hour at room temperature. -
Immunohistochemical analysis of paraffin-embedded human liver tissue with Rabbit anti-GAPDH antibody (ET1601-4) at 1/1,000 dilution.
The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (ET1601-4) at 1/1,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX. -
Immunohistochemical analysis of paraffin-embedded mouse liver tissue with Rabbit anti-GAPDH antibody (ET1601-4) at 1/1,000 dilution.
The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (ET1601-4) at 1/1,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX. -
Immunohistochemical analysis of paraffin-embedded rat liver tissue with Rabbit anti-GAPDH antibody (ET1601-4) at 1/1,000 dilution.
The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (ET1601-4) at 1/1,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX. -
Immunocytochemistry analysis of HeLa cells labeling GAPDH with Rabbit anti-GAPDH antibody (ET1601-4) at 1/100 dilution.
Cells were fixed in 4% paraformaldehyde for 20 minutes at room temperature, permeabilized with 0.1% Triton X-100 in PBS for 5 minutes at room temperature, then blocked with 1% BSA in 10% negative goat serum for 1 hour at room temperature. Cells were then incubated with Rabbit anti-GAPDH antibody (ET1601-4) at 1/100 dilution in 1% BSA in PBST overnight at 4 ℃. Goat Anti-Rabbit IgG H&L (iFluor™ 488, HA1121) was used as the secondary antibody at 1/1,000 dilution. PBS instead of the primary antibody was used as the secondary antibody only control. Nuclear DNA was labelled in blue with DAPI.
Beta tubulin (M1305-2, red) was stained at 1/100 dilution overnight at +4℃. Goat Anti-Mouse IgG H&L (iFluor™ 594, HA1126) was used as the secondary antibody at 1/1,000 dilution. -
Immunocytochemistry analysis of NIH/3T3 cells labeling GAPDH with Rabbit anti-GAPDH antibody (ET1601-4) at 1/2,500 dilution.
Cells were fixed in 4% paraformaldehyde for 20 minutes at room temperature, permeabilized with 0.1% Triton X-100 in PBS for 5 minutes at room temperature, then blocked with 1% BSA in 10% negative goat serum for 1 hour at room temperature. Cells were then incubated with Rabbit anti-GAPDH antibody (ET1601-4) at 1/2,500 dilution in 1% BSA in PBST overnight at 4 ℃. Goat Anti-Rabbit IgG H&L (iFluor™ 488, HA1121) was used as the secondary antibody at 1/1,000 dilution. PBS instead of the primary antibody was used as the secondary antibody only control. Nuclear DNA was labelled in blue with DAPI.
Beta tubulin (M1305-2, red) was stained at 1/100 dilution overnight at +4℃. Goat Anti-Mouse IgG H&L (iFluor™ 594, HA1126) was used as the secondary antibody at 1/1,000 dilution. -
Flow cytometric analysis of HeLa cells labeling GAPDH.
Cells were fixed and permeabilized. Then stained with the primary antibody (ET1601-4, 1μg/mL) (red) compared with Rabbit IgG Isotype Control (green). After incubation of the primary antibody at +4℃ for an hour, the cells were stained with a iFluor™ 488 conjugate-Goat anti-Rabbit IgG Secondary antibody (HA1121) at 1/1,000 dilution for 30 minutes at +4℃. Unlabelled sample was used as a control (cells without incubation with primary antibody; black).
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
引文
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应用: WB
反应种属: Human
发表时间: 2023 Oct
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Citation
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Potential role of Bcl2 in lipid metabolism and synaptic dysfunction of age-related hearing loss
Author: Yue Liu , Huasong Zhang , Cong Fan , Feiyi Liu , Shaoying Li , Juanjuan Li , Huiying Zhao , Xianhai Zeng
PMID: 37813166
应用: WB
反应种属: Rat
发表时间: 2023 Oct
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Citation
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Acetyl-coenzyme A acetyltransferase 1 promotes brown adipogenesis by activating the AMPK-PGC1α signaling pathway
Author:
PMID: 37582428
应用: WB
反应种属: Mouse
发表时间: 2023 Oct
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Citation
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IL-37 counteracts inflammatory injury in the temporomandibular joint via the intracellular pathway
Author: Jun Li , Sisi Peng , Ying Yan, et al
PMID: 38053836
应用: WB
反应种属: Human
发表时间: 2023 Nov
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Citation
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Silencing of PD-1 combined with EBV-specific killer T cells for the treatment of EBV-associated B lymphoma
Author: Wang J, Xu Z, Lai Y, et al
PMID: 38039947
应用: WB
反应种属: Mouse
发表时间: 2023 Nov
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Citation
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IRE1α/XBP-1 promotes β-catenin signaling activation of airway epithelium in lipopolysaccharide-induced acute lung injury
Author: Zhang H, Li J, Wang X, et al
PMID: 37935327
应用: WB
反应种属: Mouse
发表时间: 2023 Nov
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Citation
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The anticancer mechanisms of exopolysaccharide from Weissella cibaria D-2 on colorectal cancer via apoptosis induction
Author: Yurong Du , Lei Liu , Weiliang Yan
PMID: 38036594
应用: WB
反应种属: Human
发表时间: 2023 Nov
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Citation
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Human TFF2-Fc fusion protein alleviates DSS-induced ulcerative colitis in C57BL/6 mice by promoting intestinal epithelial cells repair and inhibiting macrophage inflammation
Author:
PMID: 37129719
应用: WB
反应种属: Mouse
发表时间: 2023 May
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Citation
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DSS-induced acute colitis causes dysregulated tryptophan metabolism in brain: an involvement of gut microbiota
Author:
PMID: 36758839
应用: WB
反应种属: Mouse
发表时间: 2023 May
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Citation
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Glucagon-Like Peptide-1 Inhibits the Progression of Abdominal Aortic Aneurysm in Mice: The Earlier, the Better
Author:
PMID: 37145254
应用: WB
反应种属: Mouse
发表时间: 2023 May
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Citation
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dCas9-Based PDGFR-β Activation ADSCs Accelerate Wound Healing in Diabetic Mice through Angiogenesis and ECM Remodeling
Author: Li, Y., Li, D., You, L., Deng, T., Pang, Q., Meng, X., & Zhu, B.
PMID: 36983022
应用: WB
反应种属: Mouse,Human
发表时间: 2023 Mar
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Citation
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Cyclic tensile force modifies calvarial osteoblast function via the interplay between ERK1/2 and STAT3
Author: Xiao, X., Zou, S., & Chen, J.
PMID: 36890454
应用: WB
反应种属: Mouse
发表时间: 2023 Mar
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Citation
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Design, Synthesis, and Biological Evaluation of Sulfonamide Methoxypyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors
Author:
PMID: 36986560
应用: WB
反应种属: human
发表时间: 2023 Mar
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Citation
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LAMP5 may promote MM progression by activating p38
Author: Chen, Y., & Ma, T.
PMID: 37033323
应用: WB
反应种属: Human
发表时间: 2023 Mar
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Citation
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Mangiferin relieves CCl4-induced liver fibrosis in mice
Author:
PMID: 36914687
应用: WB
反应种属: mouse
发表时间: 2023 Mar
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Citation
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Methylprednisolone Promotes Mycobacterium smegmatis Survival in Macrophages through NF-κB/DUSP1 Pathway
Author:
PMID: 36985341
应用: WB
反应种属: mouse
发表时间: 2023 Mar
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Citation
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The Mechanosensitive Piezo1 Channel Mediates Mechanochemical Transmission in Myopic Eyes
Author: Zhong, W., Lan, C., Gu, Z., Tan, Q., Xiang, X., Zhou, H., & Liao, X.
PMID: 37261388
应用: WB
反应种属:
发表时间: 2023 Jun
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Citation
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Stratifin promotes the growth and proliferation of hepatocellular carcinoma
Author:
PMID: 36996719
应用: WB
反应种属: Human
发表时间: 2023 Jun
-
Citation
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Lactobacillus plantarum LLY-606 supplementation ameliorates hyperuricemia via modulating intestinal homeostasis and relieving inflammation.
Author:
PMID: 37264705
应用: WB
反应种属: Mouse
发表时间: 2023 Jun
-
Citation
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Aminopeptidase MNP-1 triggers intestine protease production by activating daf-16 nuclear location to degrade pore-forming toxins in Caenorhabditis elegans
Author:
PMID: 37440595
应用: WB
反应种属: C. elegans
发表时间: 2023 Jul
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Citation
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Bone marrow mesenchymal stem cell-derived exosomes loaded with miR-26a through the novel immunomodulatory peptide DP7-C can promote osteogenesis
Author:
PMID: 37195490
应用: WB
反应种属: Rat
发表时间: 2023 Jul
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Citation
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Identification of a novel role for TL1A/DR3 deficiency in acute respiratory distress syndrome that exacerbates alveolar epithelial disruption
Author: Zhang, D., Zhang, J., Zhang, J., Ji, X., Qi, Q., Xu, J., Pan, Y., Liu, X., Sun, F., Zeng, R., & Dong, L.
PMID: 37434162
应用: WB
反应种属: Mouse
发表时间: 2023 Jul
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Citation
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Renal ectopic lipid deposition in rats with early-stage diabetic nephropathy evaluated by the MR mDixon-Quant technique: association with the expression of SREBP-1 and PPARα in renal tissue
Author:
PMID: 37456311
应用: WB
反应种属: Mouse
发表时间: 2023 Jul
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Citation
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Andrographolide induced ferroptosis in multiple myeloma cells by regulating the P38/Nrf2/HO-1 pathway
Author:
PMID: 37172672
应用: WB
反应种属: Human
发表时间: 2023 Jul
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Citation
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EYE-503: A Novel Retinoic Acid Drug for Treating Retinal Neurodegeneration
Author:
PMID: 37513944
应用: WB
反应种属: Mouse
发表时间: 2023 Jul
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Citation
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PD-1/PD-L1 blockade is a potent adjuvant in treatment of Staphylococcus aureus osteomyelitis in mice
Author:
PMID: 36104974
应用: WB
反应种属: Mouse
发表时间: 2023 Jan
-
Citation
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Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons
Author: Zheng, H. L., Sun, S. Y., Jin, T., Zhang, M., Zeng, Y., Liu, Q., Yang, K., Wei, R., Pan, Z., & Lin, F.
PMID: 36604795
应用: WB
反应种属: Mouse
发表时间: 2023 Jan
-
Citation
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DSS-induced colitis activates the kynurenine pathway in serum and brain by affecting IDO-1 and gut microbiota
Author: Zhao, L. P., Wu, J., Quan, W., Zhou, Y., Hong, H., Niu, G. Y., Li, T., Huang, S. B., Qiao, C. M., Zhao, W. J., Cui, C., & Shen, Y. Q.
PMID: 36776388
应用: WB
反应种属: Mouse
发表时间: 2023 Jan
-
Citation
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Analysis of the expression and prognostic significance of DDK complex in Hepatocarcinoma
Author: Wang, M., Qiu, Z. H., Wang, Y. Z., Lian, B., Bai, J. K., Zhou, Y. J., & Ji, H. J.
PMID: 36609254
应用: WB
反应种属: Human
发表时间: 2023 Jan
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Citation
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Roles of PADI4 in the expression of cytokines involved in inflammation and adhesion in differentiated NB4 cells treated with ATRA
Author: Sun, X., Mu, X., Li, F., Wang, Y., Yang, X., & Guo, Q.
PMID: 36815967
应用: WB
反应种属: Human
发表时间: 2023 Jan
-
Citation
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(Pro)renin receptor promotes colorectal cancer progression through inhibiting the NEDD4L-mediated Wnt3 ubiquitination and modulating gut microbiota
Author: Wang, J., Ding, Y., Li, D., Zhu, N., Nishiyama, A., & Yuan, Y.
PMID: 36597142
应用: WB
反应种属: Human
发表时间: 2023 Jan
-
Citation
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Overexpression of the FERONIA receptor kinase MdMRLK2 confers apple drought tolerance by regulating energy metabolism and free amino acids production
Author: Jing Y, Liu C, Liu B, et al
PMID: 35972799
应用: WB
反应种属:
发表时间: 2023 Jan
-
Citation
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Spatial and temporal alterations of developing oligodendrocytes induced by repeated sevoflurane exposure in neonatal mice
Author:
PMID: 36495605
应用: WB
反应种属: Mouse
发表时间: 2023 Jan
-
Citation
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Carvedilol exhibits anti-acute T lymphoblastic leukemia effect in vitro and in vivo via inhibiting β-ARs signaling pathway
Author:
PMID: 36495764
应用: WB
反应种属: Human
发表时间: 2023 Jan
-
Citation
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Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus
Author:
PMID: 36623760
应用: WB
反应种属: Rat
发表时间: 2023 Feb
-
Citation
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Palmitoyl Transferase FonPAT2-Catalyzed Palmitoylation of the FonAP-2 Complex Is Essential for Growth, Development, Stress Response, and Virulence in Fusarium oxysporum f. sp. niveum
Author:
PMID: 36533963
应用: WB
反应种属: Fusarium oxysporum f. sp. niveum (Fon)
发表时间: 2023 Feb
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Citation
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NCOA2-induced secretion of leptin leads to fetal growth restriction via the NF-κB signaling pathway
Author:
PMID: 36923094
应用: WB
反应种属: human
发表时间: 2023 Feb
-
Citation
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Alpha-Asarone Ameliorates Neurological Dysfunction of Subarachnoid Hemorrhagic Rats in Both Acute and Recovery Phases via Regulating the CaMKII-Dependent Pathways
Author: Gao, X., Li, R., Luo, L., Liao, C., Yang, H., & Mao, S.
PMID: 36781743
应用: WB
反应种属: Rat
发表时间: 2023 Feb
-
Citation
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Characterization of early myocardial inflammation in ischemia-reperfusion injury
Author: Wu, Q., Xu, R., Zhang, K., Sun, R., Yang, M., Li, K., Liu, H., Xue, Y., Xu, H., & Guo, Y.
PMID: 36814859
应用: WB
反应种属: Mouse
发表时间: 2023 Feb
-
Citation
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Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus
Author:
PMID: 36623760
应用: WB
反应种属: Rat
发表时间: 2023 Feb
-
Citation
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Overexpression of SLC35F2 is a potential prognostic biomarker for lung adenocarcinoma
Author: Qingzhu Zheng , Mingjie Li , Yingkun Qiu, et al
PMID: 38187235
应用: WB
反应种属: Human
发表时间: 2023 Dec
-
Citation
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RCN1 deficiency inhibits oral squamous cell carcinoma progression and THP-1 macrophage M2 polarization
Author: Han Liu , Haiyang Guo , Yuehan Wu , et al
PMID: 38057406
应用: WB
反应种属: Human
发表时间: 2023 Dec
-
Citation
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Saikosaponin-D induces the pyroptosis of lung cancer by increasing ROS and activating the NF-κB/NLRP3/caspase-1/GSDMD pathway
Author:
PMID: 37393521
应用: WB
反应种属: Human
发表时间: 2023 Aug
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Citation
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Deletion of the chd7 Hinders Oligodendrocyte Progenitor Cell Development and Myelination in Zebrafish
Author:
PMID: 37686337
应用: WB
反应种属: Zebrafish
发表时间: 2023 Aug
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Citation
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Protein-level mutant p53 reporters identify druggable rare precancerous clones in noncancerous tissues
Author:
PMID: 37537298
应用: WB
反应种属: Mouse
发表时间: 2023 Aug
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Citation
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Discovery of Novel 1,2,3,4-Tetrahydrobenzofuro[2,3-c]pyridine Histone Deacetylase Inhibitors for Efficient Treatment of Hepatocellular Carcinoma
Author:
PMID: 37498552
应用: WB
反应种属: Human
发表时间: 2023 Aug
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Citation
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A programmed cell death-related model based on machine learning for predicting prognosis and immunotherapy responses in patients with lung adenocarcinoma
Author:
PMID: 37671155
应用: WB
反应种属: Human
发表时间: 2023 Aug
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Citation
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Pre‐rRNA Facilitates TopBP1‐Mediated DNA Double‐Strand Break Response
Author:
PMID: 37582658
应用: WB
反应种属: Human,Mouse
发表时间: 2023 Aug
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Citation
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CILP2: A prognostic biomarker associated with immune infiltration in colorectal cancer
Author:
PMID: 37144183
应用: WB
反应种属: Human
发表时间: 2023 Apr
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Citation
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Sustained delivery of IL-10 by self-assembling peptide hydrogel to reprogram macrophages and promote diabetic alveolar bone defect healing
Author:
PMID: 36931990
应用: WB
反应种属: Mouse
发表时间: 2023 Apr
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Citation
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The Cytidine N-Acetyltransferase NAT10 Participates in Peripheral Nerve Injury-Induced Neuropathic Pain by Stabilizing SYT9 Expression in Primary Sensory Neurons
Author:
PMID: 36898834
应用: WB
反应种属: Mouse
发表时间: 2023 Apr
-
Citation
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Fibroblast Growth Factor 6 Promotes Adipocyte Progenitor Cell Proliferation for Adipose Tissue Homeostasis
Author:
PMID: 36607240
应用: WB
反应种属: Mouae
发表时间: 2023 Apr
-
Citation
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METTL3‐dependent m6A modification mediates bladder remodeling after partial bladder outlet obstruction through CCN2 activation
Author:
PMID: 37455557
应用: WB
反应种属: Rat
发表时间: 2023
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Citation
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Apatinib Inhibits Bladder Cancer through Suppression of the VEGFR2-PI3K-AKT Signaling Pathway as Revealed by Network Pharmacology and in vitro Experimental Verification
Author:
PMID: 36852790
应用: WB
反应种属: Human
发表时间: 2023
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Citation
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TPP1 inhibits DNA damage response and chemosensitivity in esophageal cancer
Author:
PMID: 37606165
应用: WB
反应种属: Human
发表时间: 2023
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Citation
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NORAD promotes multiple myeloma cell progression via BMP6/P-ERK1/2 axis
Author: Ma, T., Chen, Y., Yi, Z. G., Liu, J., Li, Y. H., Bai, J., Tie, W. T., Huang, M., Zhu, X. F., Wang, J., Du, J., Zuo, X. Q., Li, Q., Lin, F. L., Tang, L., Guo, J., Xiao, H. W., Lei, Q., Ma, X. L., Li, L. J., … Zhang, L. S.
PMID: 36126794
应用:
反应种属:
发表时间: 2022 Sept
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Citation
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MYOZ1 Gene Promotes Muscle Growth and Development in Meat Ducks
Author: Zhou, T., Wu, Y., Bi, Y., Bai, H., Jiang, Y., Chen, G., Chang, G., & Wang, Z.
PMID: 36140742
应用: WB
反应种属: Ducks
发表时间: 2022 Sept
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Citation
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Effect of Kaempferol on the Biological Behavior of Human Colon Cancer via Regulating MMP1, MMP2, and MMP9
Author: Zhang, X., Fan, J., Guo, F., Huang, H., Xue, J., Wu, X., & Li, T.
PMID: 36147444
应用: WB
反应种属: Human
发表时间: 2022 Sept
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Citation
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miR-210-3p suppresses osteogenic differentiation of MC3T3-E1 by targeting brain derived neurotrophic factor (BDNF)
Author: Deng, L., Lai, S., Fan, L., Li, X., Huang, H., & Mu, Y.
PMID: 36104705
应用: WB
反应种属: Mouse
发表时间: 2022 Sept
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Citation
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Downregulation of fibulin-4 inhibits autophagy and promotes the sensitivity of esophageal squamous cell carcinoma cells to apatinib by activating the Akt-mTOR signaling pathway
Author: Chen, X., Wang, J., Song, L., Yu, Y., Shi, M., Jiang, W., Liu, X., & He, X.
PMID: 35950373
应用: WB
反应种属: Human
发表时间: 2022 Sept
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Citation
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Integrative analysis reveals histone demethylase LSD1 promotes RNA polymerase II pausing
Author: Kim, H. J., Li, P., Kim, T., Oldfield, A. J., Zheng, X., & Yang, P.
PMID: 36124234
应用: WB
反应种属:
发表时间: 2022 Sept
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Citation
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Development of a highly sensitive Gaussia luciferase immunoprecipitation assay for the detection of antibodies against African swine fever virus
Author:
PMID: 36189357
应用: WB
反应种属: Human
发表时间: 2022 Sept
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Citation
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Modified Montmorillonite Improved Growth Performance of Broilers by Modulating Intestinal Microbiota and Enhancing Intestinal Barriers, Anti-Inflammatory Response, and Antioxidative Capacity
Author:
PMID: 36139873
应用: WB
反应种属: Chicken
发表时间: 2022 Sept
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Citation
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Mitochondrial Porin Is Involved in Development, Virulence, and Autophagy in Fusarium graminearum
Author:
PMID: 36135661
应用: WB
反应种属: Strain
发表时间: 2022 Sept
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Citation
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Hypomethylated gene RAC3 induces cell proliferation and invasion by increasing FASN expression in endometrial cancer
Author:
PMID: 35917927
应用: WB
反应种属: Human
发表时间: 2022 Sep
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Citation
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Shikonin induces ferroptosis in multiple myeloma via GOT1-mediated ferritinophagy
Author: Li, W., Fu, H., Fang, L., Chai, H., Gao, T., Chen, Z., & Qian, S.
PMID: 36387145
应用: WB
反应种属: Human
发表时间: 2022 Oct
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Citation
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Overexpression of adrenomedullin (ADM) alleviates the senescence of human dental pulp stem cells by regulating the miR-152/CCNA2 pathway
Author: Dou, W., Xie, J., Chen, J., Zhou, J., Xu, Z., Wang, Z., & Zhu, Q.
PMID: 36310381
应用: WB
反应种属: Human
发表时间: 2022 Oct
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Citation
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Dynamin-Related Protein 1 Is Involved in Mitochondrial Damage, Defective Mitophagy, and NLRP3 Inflammasome Activation Induced by MSU Crystals
Author: Jiang, H., Chen, F., Song, D., Zhou, X., Ren, L., & Zeng, M.
PMID: 36338340
应用: WB
反应种属: Mouse
发表时间: 2022 Oct
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Citation
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Identification of nanoparticle-mediated siRNA-ASPN as a key gene target in the treatment of keloids
Author:
PMID: 36394011
应用: WB
反应种属: Mouse
发表时间: 2022 Oct
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Citation
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Chemoprevention of 4NQO-Induced Mouse Tongue Carcinogenesis by AKT Inhibitor through the MMP-9/RhoC Signaling Pathway and Autophagy
Author:
PMID: 36247874
应用: WB
反应种属: Human
发表时间: 2022 Oct
-
Citation
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Icariin alleviates osteoarthritis through PI3K/Akt/mTOR/ULK1 signaling pathway
Author:
PMID: 36253872
应用: WB
反应种属: Human
发表时间: 2022 Oct
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Citation
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Lycium barbarum polysaccharide‐glycoprotein promotes osteogenesis in hPDLSCs via ERK activation
Author:
PMID: 36250230
应用: WB
反应种属: Human
发表时间: 2022 Oct
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Citation
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Human UFSP1 translated from an upstream near-cognate initiation codon functions as an active UFM1-specific protease
Author:
PMID: 35525273
应用: WB
反应种属: Human
发表时间: 2022 May
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Citation
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SGK1‐targeted TRPV1 regulates bladder smooth muscle cell proliferation due to BOO in mice via NFAT2
Author: He, J., Yang, J., Chen, L., He, P., Liu, X., Wang, K., Dong, T., Li, J., Ma, X., Bastian, A., & Arnulf, S.
PMID: 35148462
应用: WB
反应种属: Mouse
发表时间: 2022 May
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Citation
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Glycyrrhetinic acid restricts mitochondrial energy metabolism by targeting SHMT2
Author: Jin, X., Li, L., Peng, Q., Gan, C., Gao, L., He, S., Tan, S., Pu, W., Liu, Y., Gong, Y., Yao, Y., Wang, G., Liu, X., Gong, M., Lei, P., Zhang, H., Qi, S., Xu, H., Hu, H., Dong, B., … Dai, L.
PMID: 35602963
应用: WB
反应种属: Human
发表时间: 2022 May
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Citation
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N-acetylcholine receptors regulate cytokines expression and neutrophils recruitment via MAPK/ERK signaling in zebrafish
Author:
PMID: 34883109
应用: WB
反应种属: Zebrafish
发表时间: 2022 Mar
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Citation
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TL1A/DR3 Axis, A Key Target of TNF-a, Augments the Epithelial–Mesenchymal Transformation of Epithelial Cells in OVA-Induced Asthma
Author: Zhang, D., Yang, H., Dong, X. L., Zhang, J. T., Liu, X. F., Pan, Y., Zhang, J., Xu, J. W., Wang, Z. H., Cui, W. J., & Dong, L.
PMID: 35359966
应用: WB
反应种属: Human
发表时间: 2022 Mar
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Citation
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Hypoxia regulates cytokines expression and neutrophils migration by ERK signaling in zebrafish
Author:
PMID: 35569778
应用: WB
反应种属: Zebrafish
发表时间: 2022 Jun
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Citation
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A Temporal PROTAC Cocktail-Mediated Sequential Degradation of AURKA Abrogates Acute Myeloid Leukemia Stem Cells
Author: Liu, F., Wang, X., Duan, J., Hou, Z., Wu, Z., Liu, L., Lei, H., Huang, D., Ren, Y., Wang, Y., Li, X., Zhuo, J., Zhang, Z., He, B., Yan, M., Yuan, H., Zhang, L., Yan, J., Wen, S., Wang, Z., … Liu, Q.
PMID: 35652200
应用:
反应种属:
发表时间: 2022 Jun
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Citation
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Dietary Supplement of Anoectochilus roxburghii (Wall.) Lindl. Polysaccharides Ameliorates Cognitive Dysfunction Induced by High Fat Diet via “Gut-Brain” Axis
Author:
PMID: 35762015
应用: WB
反应种属: Mouse
发表时间: 2022 Jun
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Citation
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LncRNA KCNQ1OT1 promotes osteogenic differentiation via miR-205-5p/RICTOR axis
Author:
PMID: 35341776
应用: WB
反应种属: Human
发表时间: 2022 Jun
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Citation
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Agrimonolide inhibits cancer progression and induces ferroptosis and apoptosis by targeting SCD1 in ovarian cancer cells
Author:
PMID: 35526323
应用: WB
反应种属: Human
发表时间: 2022 Jul
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Citation
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The LAMMER Kinase MoKns1 Regulates Growth, Conidiation and Pathogenicity in Magnaporthe oryzae
Author:
PMID: 35897680
应用: WB
反应种属: Magnaporthe oryzae
发表时间: 2022 Jul
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Citation
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Vitamin D Receptor Genetic Polymorphisms Associate With a Decreased Susceptibility to Extremity Osteomyelitis Partly by Inhibiting Macrophage Apoptosis Through Inhibition of Excessive ROS Production via VDR-Bmi1 Signaling
Author: Zhao, X. Q., Wan, H. Y., He, S. Y., Qin, H. J., Yu, B., & Jiang, N.
PMID: 35957979
应用: WB
反应种属: S.aureus,Human
发表时间: 2022 Jul
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Citation
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Identification and validation of HOXD3 and UNC5C as molecular signatures in keloid based on weighted gene co-expression network analysis
Author:
PMID: 35709926
应用: WB
反应种属: Human
发表时间: 2022 Jul
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Citation
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The Role of microRNA-133 in Hemocyte Proliferation and Innate Immunity of Scylla paramamosain
Author:
PMID: 35154084
应用: WB
反应种属:
发表时间: 2022 Jan
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Citation
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Natural Flavonoid Pectolinarigenin Alleviated Hyperuricemic Nephropathy via Suppressing TGFβ/SMAD3 and JAK2/STAT3 Signaling Pathways
Author: Ren, Q., Wang, B., Guo, F., Huang, R., Tan, Z., Ma, L., & Fu, P.
PMID: 35153751
应用: WB
反应种属: Mouse
发表时间: 2022 Jan
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Citation
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The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway
Author: Zhang, Y., Huang, Q., Wang, S., Liao, Z., Jin, H., Huang, S., Hong, X., Liu, Y., Pang, J., Shen, Q., Wang, Q., Li, C., & Ji, L.
PMID: 35296033
应用: WB
反应种属: Mouse
发表时间: 2022 Feb
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Citation
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Comprehensive Pan-Cancer Analyses of Immunogenic Cell Death as a Biomarker in Predicting Prognosis and Therapeutic Response
Author: Wang, Y., Huang, Y., Yang, M., Yu, Y., Chen, X., Ma, L., Xiao, L., Liu, C., Liu, B., & Yuan, X.
PMID: 36497433
应用: WB
反应种属: Human
发表时间: 2022 Dec
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Citation
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Targeted Inhibition of Tumor Inflammation and Tumor-Platelet Crosstalk by Nanoparticle-Mediated Drug Delivery Mitigates Cancer Metastasis
Author: Li, S., Li, L., Lin, X., Chen, C., Luo, C., & Huang, Y.
PMID: 34873906
应用: WB
反应种属: Mouse
发表时间: 2022 Dec
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Citation
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Effect of SNHG11/miR-7-5p/PLCB1 Axis on Acute Pancreatitis through Inhibiting p38MAPK Pathway
Author: Song, T. J., Ke, J., Chen, F., Zhang, J. Y., Zhang, C., & Chen, H. Y.
PMID: 36611865
应用: WB
反应种属: Human
发表时间: 2022 Dec
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Citation
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From Initiation to Maintenance: HIV-1 Gp120-induced Neuropathic Pain Exhibits Different Molecular Mechanisms in the Mouse Spinal Cord Via Bioinformatics Analysis Based on RNA Sequencing
Author:
PMID: 35059976
应用: WB
反应种属: Mouse
发表时间: 2022 Dec
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Citation
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Negative Regulatory Role of the Spring Viremia of Carp Virus Matrix Protein in the Host Interferon Response by Targeting the MAVS/TRAF3 Signaling Axis
Author: Wang, Y. Y., Chen, Y. L., Ji, J. F., Fan, D. D., Lin, A. F., Xiang, L. X., & Shao, J. Z.
PMID: 35913215
应用: WB
反应种属: Zebrafish
发表时间: 2022 Aug
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Citation
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Suppression of VEGFD expression by S-nitrosylation promotes the development of lung adenocarcinoma
Author:
PMID: 35941690
应用: WB
反应种属: Mouse
发表时间: 2022 Aug
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Citation
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Effect of fecal microbiota transplantation on the TGF-β1/Smad signaling pathway in rats with TNBS-induced colitis
Author:
PMID: 36034975
应用: WB
反应种属: Rat
发表时间: 2022 Aug
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Citation
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Intra-bone marrow injection of magnesium isoglyrrhizinate inhibits inflammation and delays osteoarthritis progression through the NF-κB pathway
Author:
PMID: 36045373
应用: WB
反应种属: Rabbit
发表时间: 2022 Aug
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Citation
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miRNA-10a-5p Targeting the BCL6 Gene Regulates Proliferation, Differentiation and Apoptosis of Chicken Myoblasts
Author: Zhang, G., Zhang, X., Zhou, K., Ling, X., Zhang, J., Wu, P., Zhang, T., Xie, K., & Dai, G.
PMID: 36076940
应用: WB
反应种属: Chicken
发表时间: 2022 Aug
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Citation
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Canonical Wnt signaling works downstream of iron overload to prevent ferroptosis from damaging osteoblast differentiation
Author:
PMID: 35752374
应用: WB
反应种属: Mouse
发表时间: 2022 Aug
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Citation
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PGK1-coupled HSP90 stabilizes GSK3β expression to regulate the stemness of breast cancer stem cells
Author:
PMID: 34403222
应用: WB
反应种属: Human
发表时间: 2022 Aug
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Citation
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Fraxinellone Induces Hepatotoxicity in Zebrafish through Oxidative Stress and the Transporters Pathway
Author:
PMID: 35566003
应用: WB
反应种属: Zebrafish
发表时间: 2022 Apr
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Citation
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A sustained release of BMP2 in urine-derived stem cells enhances the osteogenic differentiation and the potential of bone regeneration
Author: Wu, S., Chen, Z., Yu, X., Duan, X., Chen, J., Liu, G., Gong, M., Xing, F., Sun, J., Huang, S., & Xiang, Z.
PMID: 35529046
应用: WB
反应种属: Human
发表时间: 2022 Apr
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Citation
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A Subunit of ESCRT-III, MoIst1, Is Involved in Fungal Development, Pathogenicity, and Autophagy in Magnaporthe oryzae
Author:
PMID: 35463448
应用: WB
反应种属: Pyricularia Oryzae
发表时间: 2022 Apr
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Citation
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Antioxidant and Anticancer Activities of Synthesized Methylated and Acetylated Derivatives of Natural Bromophenols
Author:
PMID: 35453471
应用: WB
反应种属: Human
发表时间: 2022 Apr
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Citation
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Bromophenol Bis (2,3,6-Tribromo-4,5-dihydroxybenzyl) Ether Protects HaCaT Skin Cells from Oxidative Damage via Nrf2-Mediated Pathways
Author:
PMID: 34573068
应用: WB
反应种属: Human
发表时间: 2021 Sep
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Citation
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Marine Bromophenol Bis(2,3,6-Tribromo-4,5-Dihydroxybenzyl)ether Inhibits Angiogenesis in Human Umbilical Vein Endothelial Cells and Reduces Vasculogenic Mimicry in Human Lung Cancer A549 Cells
Author:
PMID: 34822512
应用: WB
反应种属: Human
发表时间: 2021 Nov
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Citation
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Cordycepin inhibits inflammatory responses through suppression of ERK activation in zebrafish. Developmental and comparative immunology, 124, 104178. Advance online publication.
Author: Liu, W., Zhang, L., Sun, S., Tang, L. S., He, S. M., Chen, A. Q., Yao, L. N., & Ren, D. L.
PMID: 34157317
应用: WB
反应种属: Zebrafish
发表时间: 2021 Nov
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Citation
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Syndecan-1 Shedding by Matrix Metalloproteinase-9 Signaling Regulates Alveolar Epithelial Tight Junction in Lipopolysaccharide-Induced Early Acute Lung Injury
Author: Zhang, D., Zhang, J. T., Pan, Y., Liu, X. F., Xu, J. W., Cui, W. J., Qiao, X. R., & Dong, L.
PMID: 34764672
应用: WB
反应种属: Mouse
发表时间: 2021 Nov
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Citation
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Protective effects of berberine in a rat model of polycystic ovary syndrome mediated via the PI3K/AKT pathway
Author:
PMID: 33709493
应用: WB
反应种属: Rat
发表时间: 2021 May
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Citation
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Bacillus subtilis revives conventional antibiotics against Staphylococcus aureus osteomyelitis. Microbial cell factories, 20(1), 102.
Author: Zhang, F., Wang, B., Liu, S., Chen, Y., Lin, Y., Liu, Z., Zhang, X., & Yu, B.
PMID: 34001083
应用: WB
反应种属: Mouse
发表时间: 2021 May
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Citation
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Comprehensive evaluation of the metabolic effects of porcine CRTC3 overexpression on subcutaneous adipocytes with metabolomic and transcriptomic analyses
Author:
PMID: 33653408
应用:
反应种属:
发表时间: 2021 Mar
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Citation
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Study on the transcriptome for breast muscle of chickens and the function of key gene RAC2 on fibroblasts proliferation
Author:
PMID: 33676413
应用: WB
反应种属: chickens
发表时间: 2021 Mar
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Citation
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Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness
Author:
PMID: 33413536
应用: WB
反应种属: Human
发表时间: 2021 Jan
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Citation
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MicroRNA-27b-3p Targets the Myostatin Gene to Regulate Myoblast Proliferation and Is Involved in Myoblast Differentiation
Author:
PMID: 33671389
应用: WB
反应种属: chicken
发表时间: 2021 Feb
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Citation
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Neuropathic pain-induced cognitive dysfunction and down-regulation of neuronal pentraxin 2 in the cortex and hippocampus
Author:
PMID: 33512875
应用: WB
反应种属: Mouse
发表时间: 2021 Feb
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Citation
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PNSA, a Novel C-Terminal Inhibitor of HSP90, Reverses Epithelial–Mesenchymal Transition and Suppresses Metastasis of Breast Cancer Cells In Vitro
Author:
PMID: 33672529
应用: WB
反应种属: human
发表时间: 2021 Feb
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Citation
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AMPK-PINK1/Parkin Mediated Mitophagy Is Necessary for Alleviating Oxidative Stress-Induced Intestinal Epithelial Barrier Damage and Mitochondrial Energy Metabolism Dysfunction in IPEC-J2
Author:
PMID: 34943113
应用: WB
反应种属: Pig
发表时间: 2021 Dec
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Citation
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The Antioxidant Phytochemical Schisandrin A Promotes Neural Cell Proliferation and Differentiation after Ischemic Brain Injury
Author:
PMID: 34946548
应用: WB
反应种属: Mouse
发表时间: 2021 Dec
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Citation
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Gsα deficiency facilitates cardiac remodeling via CREB/ Bmp10-mediated signaling
Author: Yin, P., Li, D., Zhao, Q., Cai, M., Wu, Z., Shi, Y., & Su, L.
PMID: 34907172
应用: WB
反应种属:
发表时间: 2021 Dec
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Citation
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Expression, clinical significance and correlation of RUNX3 and HER2 in colorectal cancer
Author: Wu, Y., Xue, J., Li, Y., Wu, X., Qu, M., Xu, D., & Shi, Y.
PMID: 34532112
应用: WB
反应种属:
发表时间: 2021 Aug
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Citation
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Identification of the molecular targets and mechanisms of compound mylabris capsules for hepatocellular carcinoma treatment through network pharmacology and bioinformatics analysis
Author:
PMID: 33932512
应用: WB
反应种属: Rat
发表时间: 2021 Aug
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Citation
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Drinking Non-nutritive Sweetness Solution of Sodium Saccharin or Rebaudioside a for Guinea Pigs: Influence on Histologic Change and Expression of Sweet Taste Receptors in Testis and Epididymis
Author:
PMID: 34422887
应用: WB
反应种属: Pig
发表时间: 2021 Aug
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Citation
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Tumor-derived HMGB1 induces CD62Ldim neutrophil polarization and promotes lung metastasis in triple-negative breast cancer
Author: Jian Huang
PMID: 32943604
应用: WB
反应种属: Mouse
发表时间: 2020 Sep
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Citation
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Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer’s disease mouse model
Author: Jie Wu ;Ayaz Najafov;Hongguang Xia
PMID: 33184293
应用: WB,COIP
反应种属: human
发表时间: 2020 Nov
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Citation
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Myricetin Modulates Macrophage Polarization and Mitigates Liver Inflammation and Fibrosis in a Murine Model of Nonalcoholic Steatohepatitis
Author:
PMID: 32195263
应用: WB
反应种属: mouse
发表时间: 2020 Mar
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Citation
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LASS2 regulates hepatocyte steatosis by interacting with NDUFS2/ OXPHOS related proteins
Author:
PMID: 32279995
应用: WB
反应种属:
发表时间: 2020 Jun
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Citation
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The Effect of Shen Qi Wan Medicated Serum on NRK-52E Cells Proliferation and Migration by Targeting Aquaporin 1 (AQP1)
Author:
PMID: 32491998
应用: WB
反应种属: Rat
发表时间: 2020 Jun
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Citation
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Iron Oxide Nanoparticles as Autophagy Intervention Agents Suppress Hepatoma Growth by Enhancing Tumoricidal Autophagy
Author:
PMID: 32832347
应用: WB
反应种属: Human
发表时间: 2020 Jun
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Citation
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CAMKIIγ is a targetable driver of multiple myeloma through CaMKIIγ/ Stat3 axis
Author:
PMID: 32658867
应用: WB
反应种属: Human
发表时间: 2020 Jul
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Citation
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Luteolin-7-methylether from Leonurus japonicus inhibits estrogen biosynthesis in human ovarian granulosa cells by suppression of aromatase (CYP19)
Author:
PMID: 32360836
应用: WB
反应种属: human
发表时间: 2020 Jul
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Citation
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MicroRNA-125a-mediated regulation of the mevalonate signaling pathway contributes to high glucose-induced proliferation and migration of vascular smooth muscle cells
Author: Shen-jiang Hu
PMID: 32319638
应用: WB
反应种属: human
发表时间: 2020 Jul
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Citation
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Identification of Gliotoxin isolated from marine fungus as a new pyruvate kinase M2 inhibitor
Author:
PMID: 32507600
应用: WB
反应种属: Human
发表时间: 2020 Jul
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Citation
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FgRad50 Regulates Fungal Development, Pathogenicity, Cell Wall Integrity and the DNA Damage Response in Fusarium graminearum
Author:
PMID: 31998262
应用: WB
反应种属: Fusarium graminearum
发表时间: 2020 Jan
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Citation
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Couplet medicines of leech and centipede granules improve erectile dysfunction via inactivation of the CaSR/PLC/PKC signaling in streptozotocin-induced diabetic rats
Author:
PMID: 31922200
应用: WB
反应种属: Rat
发表时间: 2020 Feb
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Citation
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Antenatal Corticosteroid Therapy Attenuates Angiogenesis Through Inhibiting Osteoclastogenesis in Young Mice
Author: Bin Yu;Xianrong Zhang
PMID: 33384997
应用: WB
反应种属: Mouse
发表时间: 2020 Dec
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Citation
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MoSec61β, the beta subunit of Sec61, is involved in fungal development and pathogenicity, plant immunity, and ER-phagy in Magnaporthe oryzae
Author:
PMID: 33200669
应用: WB
反应种属: Magnaporthe oryzae
发表时间: 2020 Dec
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Citation
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Breed difference and regulatory role of CRTC3 in porcine intramuscular adipocyte
Author:
PMID: 32400010
应用: WB
反应种属: guinea pigs
发表时间: 2020 Aug
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Citation
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UTMD inhibit EMT of breast cancer through the ROS/miR-200c/ZEB1 axis
Author:
PMID: 32313093
应用: WB
反应种属: Human
发表时间: 2020 Apr
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Citation
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The E3 ubiquitin ligase STUB1 attenuates cell senescence bypromoting the ubiquitination and degradation of the corecircadian regulator BMAL1
Author:
PMID: 32041778
应用: WB
反应种属: human
发表时间: 2020
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Citation
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Influences of non‐nutritive sweeteners on ovarian and uterine expression of T1R2 and T1R3 in peripubertal female guinea pigs
Author:
PMID: 32219957
应用: WB
反应种属: guinea pigs
发表时间: 2020
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Citation
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Coptisine from Coptis chinensis blocks NLRP3 inflammasome activation by inhibiting caspase-1.
Author:
PMID: 31336157
应用: WB
反应种属: Mouse
发表时间: 2019 Sep
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Citation
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Elevated expression of GNAS promotes breast cancer cell proliferation and migration via the PI3K/AKT/Snail1/E-cadherin axis.
Author:
PMID: 30767161
应用: WB
反应种属: Human
发表时间: 2019 Sep
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Citation
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The role of EGFR signaling in age-related osteoporosis in mouse cortical bone
Author: Liu, G., Xie, Y., Su, J., Qin, H., Wu, H., Li, K., Yu, B., & Zhang, X.
PMID: 31298955
应用: WB
反应种属: Mouse
发表时间: 2019 Oct
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Citation
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Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAVS
Author:
PMID: 31685995
应用: WB
反应种属: Human
发表时间: 2019 Nov
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Citation
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Cereblon attenuates DNA damage-induced apoptosis by regulating the transcriptionindependent function of p53
Author:
PMID: 30683842
应用: WB
反应种属: Mouse
发表时间: 2019 Jan
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Citation
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Theaflavin attenuates cerebral ischemia/reperfusion injury by abolishing miRNA-128-3p-mediated Nrf2 inhibition and reducing oxidative stress
Author: Li Fei,Jianhong Zhu
PMID: 31638230
应用: WB
反应种属: rat
发表时间: 2019 Dec
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Citation
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Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
Author:
PMID: 31121485
应用: WB
反应种属: Mouse
发表时间: 2019 Aug
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Citation
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Chronic intermittent hypobaric hypoxia attenuates skeletal muscle ischemia-reperfusion injury in mice.
Author:
PMID: 31173783
应用: WB
反应种属: mouse
发表时间: 2019 Aug
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Citation
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Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
Author:
PMID: 31121485
应用: WB
反应种属: Mouse
发表时间: 2019 Aug
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Citation
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AMSC-derived exosomes alleviate lipopolysaccharide/d-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages
Author:
PMID: 30197023
应用: WB
反应种属: Mouse
发表时间: 2018 Oct
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Citation
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Rapid Communication: Porcine CRTC3 gene clone, expression pattern, and its regulatory role in intestinal epithelial cells
Author:
PMID: 29796654
应用: WB
反应种属: Pig
发表时间: 2018 Jun
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Citation
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Increase of PRPP enhances chemosensitivity of PRPS1 mutant acute lymphoblastic leukemia cells to 5‐Fluorouracil
Author:
PMID: 30255549
应用: WB
反应种属: Human
发表时间: 2018 Dec
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Citation
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Let-7c-5p inhibits cell proliferation and induces cell apoptosis by targeting ERCC6 in breast cancer
Author:
PMID: 28731186
应用: WB
反应种属: Human
发表时间: 2017 Sep
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Citation
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Histone H3 lysine 9 methyltransferase FvDim5 regulates fungal development, pathogenicity and osmotic stress responses in Fusarium verticillioides
Author:
PMID: 28957455
应用: WB
反应种属: Fusarium verticillioides
发表时间: 2017 Oct
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Citation