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Organelle Markers - ER Markers

内质网是由扁平的、相连的囊组成的真核膜细胞器,负责膜蛋白和分泌型蛋白的合成,以及它们随后的适当折叠和翻译后修饰,内质网可分为: 粗糙内质网和平滑内质网。粗糙内质网有大量核糖体附着以合成膜和分泌型蛋白质,平滑内质网无核糖体附着,其与脂质代谢有关。内质网应激与多种疾病相关,包括癌症、糖尿病、炎性疾病和神经退行性疾病。常见内质网标记物有Calreticulin、Calnexin、KDEL、ERp72、GRP94和PDI等

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