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Anti-MEMO1 antibody

兔多抗 | 货号: HA500024


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价格:RMB   2500
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  • 概述

  • 产品描述 May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
  • 产品名称 Anti-MEMO1 antibody
  • 分子量 Predicted band size: 34 kDa.
  • 种属反应性 Human,Mouse,Rat
  • 验证应用 WB,IHC
  • 抗体类型 兔多抗
  • 免疫原 Recombinant protein within human MEMO1 aa 1-200.
  • 性能

  • 形态 Liquid
  • 浓度 1 mg/mL.
  • 存放说明 Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • 存储缓冲液 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
  • 亚型 IgG
  • 纯化方式 Protein affinity purified.
  • 亚细胞定位 Cytosol, nucleus.
  • 数据链接 SwissProt: Q9Y316 Human
    SwissProt: Q91VH6 Mouse
    SwissProt: Q4QQR9 Rat
  • 其它名称
    • C21orf19-like protein antibody
    • C2orf4 antibody
    • CGI 27 antibody
  • 应用

    WB: 1:1,000-1:2,000
    IHC: 1:100-1:500

  • 背景文献

  • 1. Marone R. et. al. Memo mediates ErbB2-driven cell motility. Nat. Cell Biol. 6:515-522(2004).
  • Publishing research using Anti-MEMO1 antibody? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols