您的当前位置: 首页 > 产品 > 产品详情 > HA720147F

2023开学季

iFluor™ 647 Conjugated Anti-Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody [SC65-06]

重组兔单抗 | 货号: HA720147F


规格:

价格:RMB   3280
现在订购,【现货】
相关产品:

暂无,点击查看热门产品

  • 概述

  • 产品描述 Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed in pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The a-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins are useful markers of tissue differentiation and, in addition, they aid in the characterization of malignant tumors. In Bowen’s disease, the characteristic malignancy of the epidermis exhibits distinct expression patterns of Cytokeratin 14. The gene encoding human Cytokeratin 14 maps to chromosome 17q12-21. Mutations in this gene lead to epidermolysis bullosa simplex, an inheritied skin disorder characterized by skin blistering due to basal keratinocyte fragility.
  • 产品名称 iFluor™ 647 Conjugated Anti-Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody [SC65-06]
  • 分子量 Predicted band size: 52 kDa
  • 种属反应性 Human,Mouse,Rat
  • 验证应用 IF-Cell,IF-Tissue
  • 抗体类型 重组兔单抗
  • 免疫原 Recombinant protein within Human Cytokeratin 14 aa 250-484.
  • 偶联 iFluor™ 647
  • 性能

  • 形态 Liquid
  • 浓度 1 mg/mL.
  • 存放说明 Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • 存储缓冲液 Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS.
  • 亚型 IgG
  • 纯化方式 Protein A affinity purified.
  • 亚细胞定位 Cytoplasm, Nucleus.
  • 数据链接 SwissProt: P02533 Human
    SwissProt: Q6IFV1 Rat
  • 其它名称
    • CK 14 antibody
    • CK-14 antibody
    • ck14 antibody
  • 应用

    IF-Cell: 1:100
    IF-Tissue: 1:400

  • 背景文献

  • 1. Pastar I. et al. Interactions of methicillin resistant Staphylococcus aureus USA300 and Pseudomonas aeruginosa in polymicrobial wound infection. PLoS One 8:e56846 (2013).

    2. DeWard AD. et al. Cellular heterogeneity in the mouse esophagus implicates the presence of a nonquiescent epithelial stem cell population. Cell Rep 9:701-11 (2014).
  • Publishing research using iFluor™ 647 Conjugated Anti-Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody? Please let us know so that we can cite the reference in this datasheet.

Choose your product,application and species below,then click "Submit".

On the next page you can complete and submit your review.

  • * Code No.
  • *Application
  • *Sample
  • Species Tested
  • Against
  • Choose text
  • Content

Leave us a review

Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols