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iFluor™ 488 Conjugated Anti-Collagen VI Recombinant Rabbit Monoclonal Antibody [SD83-03]

重组兔单抗 | 货号: HA720155F


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价格:RMB   3280
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  • 概述

  • 产品描述 This antibody is well suited to detect extracellular matrix proteins in normal as well as disease state tissues. Disruption of tissue organization is the hallmark of neoplasia. Malignant lesions can be distinguished from benign by examining the breakdown of basement membranes and loss of 3-dimensional architecture. Malignant cells are presumed to use matrix metalloproteases to degrade barriers created by the extracellular matrix which then allows metastasis to occur. Collagenases, stomelysins and gelatinases can collectively degrade all of the various components of the extracellular matrix, including fibrillar and non-fibrillar collagens and basement membrane glycoproteins.
  • 产品名称 iFluor™ 488 Conjugated Anti-Collagen VI Recombinant Rabbit Monoclonal Antibody [SD83-03]
  • 分子量 Predicted band size: 109 kDa
  • 种属反应性 Human,Mouse,Rat
  • 验证应用 IF-Cell,IF-Tissue
  • 抗体类型 重组兔单抗
  • 免疫原 Recombinant protein within Human Collagen VI aa 17-255 / 1,028.
  • 偶联 iFluor™ 488
  • RRID AB_3072093
  • 性能

  • 形态 Liquid
  • 浓度 1 mg/mL.
  • 存放说明 Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • 存储缓冲液 Preservative: 0.02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68.98% PBS
  • 亚型 IgG
  • 纯化方式 Protein A affinity purified.
  • 亚细胞定位 Extracellular matrix.
  • 数据链接 SwissProt: P12109 Human
    SwissProt: P12110 Human
    SwissProt: P12111 Human
    SwissProt: Q02788 Mouse
    SwissProt: Q04857 Mouse
  • 其它名称
    • Alpha 1 (VI) chain (61 AA) antibody
    • CO6A1_HUMAN antibody
    • COL6A1 antibody
  • 应用

    IF-Cell: 1:100
    IF-Tissue: 1:50

  • 背景文献

  • 1. Kristofik N et al. Impaired von Willebrand factor adhesion and platelet response in thrombospondin-2 knockout mice. Blood 128:1642-50 (2016).

    2. Okawa S et al. Lipopolysaccharide induces expression of collagen VI in the rat lung. J Toxicol Pathol 28:37-41 (2015).
  • Publishing research using iFluor™ 488 Conjugated Anti-Collagen VI Recombinant Rabbit Monoclonal Antibody? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols