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Anti-PI3K p85(pY467)+PI3K p55(pY199) Recombinant Rabbit Monoclonal Antibody [PSH01-38]

重组兔单抗 | 货号: HA721672


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价格:RMB   1600
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  • 概述

  • 产品描述 Phosphatidylinositol 3-kinase regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene. Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms.
  • 产品名称 Anti-PI3K p85(pY467)+PI3K p55(pY199) Recombinant Rabbit Monoclonal Antibody [PSH01-38]
  • 分子量 Predicted band size: 84 kDa/55 kDa
  • 种属反应性 Human,Mouse
  • 验证应用 WB,IF-Cell
  • 抗体类型 重组兔单抗
  • 免疫原 Synthetic peptide within human PIK3R1 aa 451-500 / 724.
  • 偶联 Non-conjugated
  • RRID AB_3072785
  • 性能

  • 形态 Liquid
  • 浓度 1 mg/mL.
  • 存放说明 Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
  • 存储缓冲液 PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • 亚型 IgG
  • 纯化方式 Protein A affinity purified.
  • 亚细胞定位 Cell-cell junction, cis-Golgi network, cytoplasm, cytosol, membrane, nucleus.
  • 数据链接 SwissProt: P27986 Human
    SwissProt: P26450 Mouse
  • 其它名称
    • GRB1 antibody
    • p85 alpha antibody
    • p85 antibody
  • 应用

    WB: 1:1,000
    IF-Cell: 1:100

  • 背景文献

  • 1. Koch PA et al. The molecular mechanisms mediating class II PI 3-kinase function in cell physiology. FEBS J. 2021 Dec

    2. Acosta-Martinez M et al. The PI3K/Akt Pathway in Meta-Inflammation. Int J Mol Sci. 2022 Dec
  • Publishing research using Anti-PI3K p85(pY467)+PI3K p55(pY199) Recombinant Rabbit Monoclonal Antibody? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols