概述
产品名称
HRP Conjugated Goat anti-Mouse IgG Goat Polyclonal Antibody
抗体类型
Goat Polyclonal Antibody
免疫原
Mouse IgG (H+L).
种属反应性
Mouse
验证应用
WB, ELISA, IHC-P
偶联
HRP
产品特性
形态
Liquid
浓度
1ug/ul
存放说明
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
存储缓冲液
1*TBS (pH7.4), 0.5%BSA, 40% Glycerol.
亚型
IgG
纯化方式
Immunogen affinity purified.
应用稀释度
-
WB
-
1:20,000- 1:80,000
-
ELISA
-
1:5,000-1:10000
-
IHC-P
-
1:50-1:100
发表文章中的应用
靶点
功能
Whole IgG antibodies are isolated as intact molecules from antisera by immunoaffinity chromatography. They have an Fc portion and two antigen binding Fab portions joined together by disulfide bonds and therefore they are divalent. The average molecular weight is reported to be about 160 kDa. The whole IgG form of antibodies is suitable for the majority of immunodetection procedures and is the most cost effective. Horseradish peroxidase (HRP) conjugates are prepared by a modified Nakane and Kawaoi procedure (J. Histochem. Cytochem. 1974. 22, 1084). Peroxidase conjugates are commonly used for immunohistochemistry, Western blotting, and ELISA. Affinity-purified anti-horseradish peroxidase and conjugates are available for detection of horseradish peroxidase antigen or for signal amplification of HRP-containing reagents. For immunostaining of mammalian cells, an advantage of using anti-horseradish peroxidase is reduced background, since the antibody does not recognize the endogenous peroxidase-like enzymes found in those cells.
背景文献
暂无
图片
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Western blot analysis of mouse anti-DNMT1 antibody (EM1901-83,1/500) and mouse anti-CAPZA1 antibody (EM1901-82, 1/500) with Daudi Cell and K562 Cell lysates (All lanes proteins at 10 µg per lane). Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody was used in 5% BSA at room temperature for 2 hours. Goat anti-mouse IgG -HRP) (HA1006) was used for 1 hour at room temperature at 1:10,000 (Lane A), 1:20,000 (Lane B), 1:40,000 (Lane C) and 1:80,000 (Lane D).
Exposure time: 60 seconds -
The Cross-reactions of the secondary antibody (HA1006) with Rabbit IgG and Human IgG.
Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. Goat anti-mouse IgG -HRP (HA1006) was used for 1 hour at room temperature at 1:5,000 (Lane A) and 1:10,000 (Lane B).
Exposure time: 2 minutes
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
引文
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Unintended Changes in Genetically Modified Rice Expressing the Lysine-Rich Fusion Protein Gene Revealed by a Proteomics Approach
Author: LIU Qiaoquan
PMID: NoPMID4
应用: WB
反应种属: Mouse
发表时间: None Nov
-
Citation
-
Omega-3 polyunsaturated fatty acids protect peritoneal mesothelial cells from hyperglycolysis and mesothelial-mesenchymal transition through the FFAR4/CaMKKβ/AMPK/mTOR signaling pathway
Author: Zhang Jing,et al
PMID: 38262160
应用: WB
反应种属: Mouse
发表时间: 2024 Jan
-
Citation
-
CyHV-2 infection triggers mitochondrial-mediated apoptosis in GiCF cells by upregulating the pro-apoptotic gene ccBAX
Author: Cheng Wenjie,et al
PMID: 38253137
应用: WB
反应种属: Zebrafish
发表时间: 2024 Jan
-
Citation
-
NAD+ dependent UPRmt activation underlies intestinal aging caused by mitochondrial DNA mutations
Author: Yang Liang,et al
PMID: 38228611
应用: WB
反应种属: Mouse
发表时间: 2024 Jan
-
Citation
-
Hippo/YAP1 promotes osteoporotic mice bone defect repair via the activating of Wnt signaling pathway
Author: Li Kehan,et al
PMID: 38184268
应用: WB
反应种属: Mouse
发表时间: 2024 Jan
-
Citation
-
Efficient generation of recombinant eggplant mottled dwarf virus and expression of foreign proteins in solanaceous hosts
Author: Wang Shuo,et al
PMID: 38215560
应用: WB
反应种属: N. benthamiana
发表时间: 2024 Jan
-
Citation
-
Overexpression of Aurora Kinase B Is Correlated with Diagnosis and Poor Prognosis in Hepatocellular Carcinoma
Author: Zhang JIn,et al
PMID: 38396874
应用: WB
反应种属: Human
发表时间: 2024 Feb
-
Citation
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Genetic association and functional validation of ZFP36L2 in non-syndromic orofacial cleft subtypes
Author: Sun Jialin,et al
PMID: 38321215
应用: WB
反应种属: Zebrafish
发表时间: 2024 Feb
-
Citation
-
Knockdown of PGC1α suppresses dysplastic oral keratinocytes proliferation through reprogramming energy metabolism
Author:
PMID: 37661238
应用:
反应种属: Human
发表时间: 2023 Sept
-
Citation
-
The transcription factor FgStuA regulates virulence and mycotoxin biosynthesis via recruiting the SAGA complex in Fusarium graminearum
Author:
PMID: 37799006
应用: WB
反应种属:
发表时间: 2023 Oct
-
Citation
-
M. tb Rv0927c suppresses the activation of HIF-1α pathway through VHL-mediated ubiquitination and NF-κB/COX-2 pathway to enhance mycobacteria survival
Author:
PMID: 37922696
应用: WB
反应种属: Mouse
发表时间: 2023 Oct
-
Citation
-
Activation of the PERK-CHOP signaling pathway during endoplasmic reticulum stress contributes to olanzapine-induced dyslipidemia
Author:
PMID: 37880338
应用: WB
反应种属: Mouse
发表时间: 2023 Oct
-
Citation
-
Plasma TNFRSF11B as a New Predictive Inflammatory Marker of Sepsis-ARDS with Endothelial Dysfunction
Author:
PMID: 37851947
应用:
反应种属:
发表时间: 2023 Oct
-
Citation
-
LASS2 enhances p53 protein stability and nuclear import to suppress liver cancer progression through interaction with MDM2/MDMX
Author: Zhao Q, He W, Liu Z, et al
PMID: 37963859
应用: WB
反应种属: Human
发表时间: 2023 Nov
-
Citation
-
LATS1/YAP1 Axis Controls Bone Regeneration on Distraction Osteogenesis by Activating Wnt/β-catenin
Author: Li K, Liu L, Liu H, Xing J, Hu P, Song J
PMID: 37930731
应用: WB
反应种属: Rat
发表时间: 2023 Nov
-
Citation
-
Krüppel-like factor 5 activates chick intestinal stem cell and promotes mucosal repair after impairment
Author: Yu L, Qi S, Wei G, et al
PMID: 37950881
应用: WB
反应种属: Chicken
发表时间: 2023 Nov
-
Citation
-
Acupuncture with specific mode electro-stimulation effectively and transiently opens the BBB through Shh signaling pathway
Author: Lin Y, Gan L, Ren L, et al
PMID: 37942738
应用: WB
反应种属: Rat
发表时间: 2023 Nov
-
Citation
-
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies
Author: Li, Y., Zhu, S., Luo, J., Tong, Y., Zheng, Y., Ji, L., He, Z., Jing, Q., Huang, J., Zhang, Y., & Bi, Q.
PMID: 37249927
应用: WB
反应种属: Mouse
发表时间: 2023 May
-
Citation
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Wheat yellow mosaic virus NIb targets TaVTC2 to elicit broad-spectrum pathogen resistance in wheat
Author: Zhang, T., Hu, H., Wang, Z., Feng, T., Yu, L., Zhang, J., Gao, W., Zhou, Y., Sun, M., Liu, P., Zhong, K., Chen, Z., Chen, J., Li, W., & Yang, J.
PMID: 36715229
应用: WB
反应种属:
发表时间: 2023 May
-
Citation
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Identification of a Specific Phage as Growth Factor Alternative Promoting the Recruitment and Differentiation of MSCs in Bone Tissue Regeneration
Author:
PMID: 37023478
应用: WB
反应种属: Mouse
发表时间: 2023 May
-
Citation
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Spleen fibroblastic reticular cell-derived acetylcholine promotes lipid metabolism to drive autoreactive B cell responses
Author:
PMID: 37019104
应用:
反应种属: Mouse
发表时间: 2023 May
-
Citation
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FOSL2 promotes intertumoral infiltration of T cells and increases pathological complete response rates in locally advanced rectal cancer patients
Author:
PMID: 36997107
应用: WB
反应种属: Mouse
发表时间: 2023 May
-
Citation
-
Nuclear DJ-1 Regulates DNA Damage Repair via the Regulation of PARP1 Activity
Author:
PMID: 37239999
应用: WB
反应种属: Mouse
发表时间: 2023 May
-
Citation
-
Scavenger receptor A-mediated nanoparticles target M1 macrophages for acute liver injury
Author:
PMID: 37274920
应用: WB
反应种属: Mouse
发表时间: 2023 May
-
Citation
-
OsCIP1, a secreted protein, binds to and stabilizes OsCR4 to promote aleurone layer development, seed germination and early seedling growth in rice
Author:
PMID: 36787850
应用:
反应种属:
发表时间: 2023 May
-
Citation
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TWIST1 rescue calcium overload and apoptosis induced by inflammatory microenvironment in S. aureus-induced osteomyelitis
Author:
PMID: 37071966
应用:
反应种属:
发表时间: 2023 Jun
-
Citation
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Panax notoginseng saponins normalises tumour blood vessels by inhibiting EphA2 gene expression to modulate the tumour microenvironment of breast cancer
Author: Xia, L., Liu, X., Mao, W., Guo, Y., Huang, J., Hu, Y., Jin, L., Liu, X., Fu, H., Du, Y., & Shou, Q.
PMID: 37060724
应用: WB
反应种属: Mouse
发表时间: 2023 Jun
-
Citation
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Vps4a Regulates Autophagic Flux to Prevent Hypertrophic Cardiomyopathy
Author:
PMID: 37445978
应用: WB
反应种属: Mouse
发表时间: 2023 Jun
-
Citation
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Integrated analysis of FKBP1A/SLC3A2 axis in everolimus inducing ferroptosis of breast cancer and anti-proliferation of T lymphocyte
Author:
PMID: 37484811
应用: WB
反应种属: Human
发表时间: 2023 Jun
-
Citation
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Induction of lysosomal exocytosis and biogenesis via TRPML1 activation for the treatment of uranium-induced nephrotoxicity
Author:
PMID: 37414766
应用: WB
反应种属: Mouse
发表时间: 2023 Jul
-
Citation
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The OsbHLH002/OsICE1-OSH1 module orchestrates secondary cell wall formation in rice
Author:
PMID: 37384532
应用: WB
反应种属: Rice
发表时间: 2023 Jul
-
Citation
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Bifidobacterium adolescentis induces Decorin+ macrophages via TLR2 to suppress colorectal carcinogenesis
Author:
PMID: 37464382
应用: WB
反应种属: Mouse
发表时间: 2023 Jul
-
Citation
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Parthenolide alleviates microglia‐mediated neuroinflammation via MAPK/TRIM31/NLRP3 signaling to ameliorate cognitive disorder
Author:
PMID: 37182449
应用: WB
反应种属: Human, Mouse
发表时间: 2023 Jul
-
Citation
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Bone marrow mesenchymal stem cell-derived exosomes loaded with miR-26a through the novel immunomodulatory peptide DP7-C can promote osteogenesis
Author:
PMID: 37195490
应用: WB
反应种属: Rat
发表时间: 2023 Jul
-
Citation
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5'-tRF-GlyGCC promotes breast cancer metastasis by increasing fat mass and obesity-associated protein demethylase activity
Author: Chen, F., Song, C., Meng, F., Zhu, Y., Chen, X., Fang, X., Ma, D., Wang, Y., & Zhang, C.
PMID: 36464183
应用: WB
反应种属: Human
发表时间: 2023 Jan
-
Citation
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PD-1/PD-L1 blockade is a potent adjuvant in treatment of Staphylococcus aureus osteomyelitis in mice
Author:
PMID: 36104974
应用: WB
反应种属: Mouse
发表时间: 2023 Jan
-
Citation
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Circular RNA circTRPS1-2 inhibits the proliferation and migration of esophageal squamous cell carcinoma by reducing the production of ribosomes
Author:
PMID: 36635258
应用: WB
反应种属: Human
发表时间: 2023 Jan
-
Citation
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Klf4-Sirt3/Pparα-Lcad pathway contributes to high phosphate-induced lipid degradation
Author:
PMID: 36624473
应用: WB
反应种属: Catfish
发表时间: 2023 Jan
-
Citation
-
Dusp1 regulates thermal tolerance limits in zebrafish by maintaining mitochondrial integrity
Author:
PMID: 36419379
应用: WB
反应种属: Human
发表时间: 2023 Jan
-
Citation
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DNA virus oncoprotein HPV18 E7 selectively antagonizes cGAS-STING-triggered innate immune activation
Author: Lou, M., Huang, D., Zhou, Z., Shi, X., Wu, M., Rui, Y., Su, J., Zheng, W., & Yu, X. F.
PMID: 36377393
应用: WB
反应种属: Human
发表时间: 2023 Jan
-
Citation
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Real-time imaging of RNA polymerase I activity in living human cells
Author:
PMID: 36282216
应用: WB
反应种属: Human
发表时间: 2023 Jan
-
Citation
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SARS‐CoV‐2 ORF3a inhibits cGAS‐STING‐mediated autophagy flux and antiviral function
Author:
PMID: 36163413
应用: WB
反应种属: Human
发表时间: 2023 Jan
-
Citation
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TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion
Author: Zheng, W., Zhou, Z., Rui, Y., Ye, R., Xia, F., Guo, F., Liu, X., Su, J., Lou, M., & Yu, X. F.
PMID: 36823147
应用: WB
反应种属: Human
发表时间: 2023 Feb
-
Citation
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NCOA2-induced secretion of leptin leads to fetal growth restriction via the NF-κB signaling pathway
Author:
PMID: 36923094
应用: WB
反应种属:
发表时间: 2023 Feb
-
Citation
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Development of stable HEK293T cell pools expressing CSFV E2 protein: A potential antigen expression platform
Author:
PMID: 36725430
应用: WB
反应种属: Human
发表时间: 2023 Feb
-
Citation
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APPL1 Is a Prognostic Biomarker and Correlated with Treg Cell Infiltration via Oxygen-Consuming Metabolism in Renal Clear Cell Carcinoma
Author: Yang, M., Gong, C., Song, K., Huang, N., Chen, H., Gong, H., Yang, Y., Guo, S., & Xiao, H.
PMID: 36846720
应用: WB
反应种属: Human
发表时间: 2023 Feb
-
Citation
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Musashi-2 Deficiency Triggers Colorectal Cancer Ferroptosis by Downregulating the MAPK Signaling Cascade to Inhibit HSPB1 Phosphorylation
Author: Meng X, Peng X, Ouyang W, et al
PMID: 38041016
应用: WB
反应种属: Mouse
发表时间: 2023 Dec
-
Citation
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AKIP1 accelerates glioblastoma progression through stabilizing EGFR expression
Author:
PMID: 37596322
应用: WB
反应种属: Mouse
发表时间: 2023 Aug
-
Citation
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HapX-mediated H2B deub1 and SreA-mediated H2A.Z deposition coordinate in fungal iron resistance
Author:
PMID: 37650633
应用: Co-IP
反应种属:
发表时间: 2023 Aug
-
Citation
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Early clues and molecular mechanism involved in neurodegenerative diseases induced in immature mice by combined exposure to polypropylene microplastics and DEHP
Author:
PMID: 37597731
应用: WB
反应种属: Mouse
发表时间: 2023 Aug
-
Citation
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Hydra gasdermin-gated pyroptosis signalling regulates tissue regeneration
Author:
PMID: 37543221
应用: WB
反应种属:
发表时间: 2023 Aug
-
Citation
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Acute aerobic exercise regulation of myocardial calcium homeostasis involves Casq1, Casq2 and Trdn
Author:
PMID: 37589058
应用: WB
反应种属: Rat
发表时间: 2023 Aug
-
Citation
-
Microglia and astrocytes mediate synapse engulfment in a MER tyrosine kinase-dependent manner after traumatic brain injury
Author:
PMID: 36751804
应用: WB
反应种属:
发表时间: 2023 Aug
-
Citation
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Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways
Author:
PMID: 36572326
应用:
反应种属:
发表时间: 2023 Apr
-
Citation
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Profiling of N6-methyladenosine methylation in porcine longissimus dorsi muscle and unravelling the hub gene ADIPOQ promotes adipogenesis in an m6A-YTHDF1-dependent manner
Author: Gong, H., Gong, T., Liu, Y., Wang, Y., & Wang, X.
PMID: 37024992
应用: WB
反应种属: Pig
发表时间: 2023 Apr
-
Citation
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Ginkgo biloba Extract Preventively Intervenes in Citrobacter Rodentium-Induced Colitis in Mice
Author: Chen, T., Chen, Y., Li, K., Chen, Z., Zhao, Q., Fan, Y., Liu, Y., Zhang, S., & Hao, Z.
PMID: 37111225
应用: WB
反应种属: Mouse
发表时间: 2023 Apr
-
Citation
-
Cyclin O promotes lung cancer progression and cetuximab resistance via cell cycle regulation and CDK13 interaction
Author: Jiang, J., Yu, W., Fang, T., Li, Y., Liang, J., Zhao, R., Feng, Z., Wang, J., & Tian, H.
PMID: 37197505
应用:
反应种属:
发表时间: 2023 Apr
-
Citation
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Evaluation of Potential Probiotic Properties of Limosilactobacillus fermentum Derived from Piglet Feces and Influence on the Healthy and E. coli-Challenged Porcine Intestine
Author:
PMID: 37110478
应用: WB
反应种属:
发表时间: 2023 Apr
-
Citation
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TPP1 inhibits DNA damage response and chemosensitivity in esophageal cancer
Author:
PMID: 37606165
应用: WB
反应种属: Human
发表时间: 2023
-
Citation
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Total alkaloids of Fritillaria unibracteata var. wabuensis bulbus ameliorate chronic asthma via the TRPV1/Ca2+/NFAT pathway
Author:
PMID: 37421766
应用: WB
反应种属: Mouse
发表时间: 2023
-
Citation
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Peficitinib ameliorates doxorubicin-induced cardiotoxicity by suppressing cellular senescence and enhances its antitumor activity
Author:
PMID: 37451017
应用: WB
反应种属: Mouse
发表时间: 2023
-
Citation
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Quercetin Protects against MPP+/MPTP-Induced Dopaminergic Neuron Death in Parkinson's Disease by Inhibiting Ferroptosis
Author: Lin, Z. H., Liu, Y., Xue, N. J., Zheng, R., Yan, Y. Q., Wang, Z. X., Li, Y. L., Ying, C. Z., Song, Z., Tian, J., Pu, J. L., & Zhang, B. R.
PMID: 36105483
应用: WB
反应种属:
发表时间: 2022 Sept
-
Citation
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Modified Montmorillonite Improved Growth Performance of Broilers by Modulating Intestinal Microbiota and Enhancing Intestinal Barriers, Anti-Inflammatory Response, and Antioxidative Capacity
Author:
PMID: 36139873
应用: WB
反应种属: Chicken
发表时间: 2022 Sept
-
Citation
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No synergistic effect of fecal microbiota transplantation and shugan decoction in water avoidance stress-induced IBS-D rat model
Author: Meng, Y., Feng, Y., Hang, L., Zhou, Y., Wang, E., & Yuan, J.
PMID: 36171751
应用: IF
反应种属: Rat
发表时间: 2022 Sept
-
Citation
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Silencing tyrosine hydroxylase or dopa decarboxylase gene disrupts cuticle tanning during larva‐pupa‐adult transformation in Henosepilachna vigintioctopunctata
Author:
PMID: 35470957
应用: WB
反应种属: Insect
发表时间: 2022 Sep
-
Citation
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Contribution of diabetes mellitus to periodontal inflammation during orthodontic tooth movement
Author:
PMID: 36050281
应用: WB
反应种属: Rat
发表时间: 2022 Sep
-
Citation
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Binding of Glycerol to Human Galectin-7 Expands Stability and Modulates Its Functions
Author:
PMID: 36293173
应用: WB
反应种属: Human
发表时间: 2022 Oct
-
Citation
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Analysis of RIOK2 Functions in Mediating the Toxic Effects of Deoxynivalenol in Porcine Intestinal Epithelial Cells
Author: Gao, Z., Xu, C., Fan, H., Wang, H., Wu, Z., Wu, S., & Bao, W.
PMID: 36361502
应用: WB
反应种属: Pig
发表时间: 2022 Oct
-
Citation
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Histone Acetyltransferase CfGcn5-Mediated Autophagy Governs the Pathogenicity of Colletotrichum fructicola
Author: Zhang, S., Guo, Y., Li, S., & Li, H.
PMID: 35975920
应用: WB
反应种属:
发表时间: 2022 Oct
-
Citation
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Boosting ferroptosis and microtubule inhibition for antitumor therapy via a carrier-free supermolecule nanoreactor
Author:
PMID: none_22102701
应用: WB,IF
反应种属: Mouse
发表时间: 2022 Oct
-
Citation
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Extracellular vesicles derived from human bone marrow stem cells inhibit acute lymphoblastic leukemia cell growth by inhibiting MAPK pathway via the miR-29b-3p/GDF15 axis
Author:
PMID: 36327876
应用: WB
反应种属:
发表时间: 2022 Nov
-
Citation
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Metformin combats obesity by targeting FTO in an m6A-YTHDF2-dependent manner
Author:
PMID: 35481401
应用: WB
反应种属: Mouse
发表时间: 2022 Nov
-
Citation
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Targeted delivery of fat extract by platelet membrane-cloaked nanocarriers for the treatment of ischemic stroke
Author: Wang, C., Yang, X., Jiang, Y., Qi, L., Zhuge, D., Xu, T., Guo, Y., Deng, M., Zhang, W., Tian, D., Yin, Q., Li, L., Zhang, Z., Wang, Y., Yang, G. Y., Chen, Y., & Tang, Y.
PMID: 35642036
应用: WB
反应种属: Mouse
发表时间: 2022 May
-
Citation
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C/EBPα Epigenetically Modulates TFF1 Expression via mC-6 Methylation in the Jejunum Inflammation Induced by a Porcine Coronavirus
Author: Qu, H., Zong, Q., Wang, H., Wu, S., Cai, D., & Bao, W.
PMID: 35693767
应用: WB
反应种属: Pig
发表时间: 2022 May
-
Citation
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Galactooligosaccharides as a protective agent for intestinal barrier and its regulatory functions for intestinal microbiota
Author: Wang, G., Wang, H., Jin, Y., Xiao, Z., Umar Yaqoob, M., Lin, Y., Chen, H., & Wang, M.
PMID: 35400418
应用: WB
反应种属:
发表时间: 2022 May
-
Citation
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Osteopontin aggravates acute lung injury in influenza virus infection by promoting macrophages necroptosis
Author: Wang, J., Li, X., Wang, Y., Li, Y., Shi, F., & Diao, H.
PMID: 35246529
应用:
反应种属: Mouse
发表时间: 2022 Mar
-
Citation
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A Selective Small‐Molecule c‐Myc Degrader Potently Regresses Lethal c‐Myc Overexpressing Tumors
Author: Xu, Y., Yu, Q., Wang, P., Wu, Z., Zhang, L., Wu, S., Li, M., Wu, B., Li, H., Zhuang, H., Zhang, X., Huang, Y., Gan, X., & Xu, R.
PMID: 35048559
应用: WB
反应种属: Mouse
发表时间: 2022 Mar
-
Citation
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Kir2.1-mediated membrane potential promotes nutrient acquisition and inflammation through regulation of nutrient transporters
Author: Yu, W., Wang, Z., Yu, X., Zhao, Y., Xie, Z., Zhang, K., Chi, Z., Chen, S., Xu, T., Jiang, D., Guo, X., Li, M., Zhang, J., Fang, H., Yang, D., Guo, Y., Yang, X., Zhang, X., Wu, Y., Yang, W., … Wang, D.
PMID: 35729093
应用: WB
反应种属:
发表时间: 2022 Jun
-
Citation
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(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H2O2 Through Activation of Nrf2 Pathway
Author: Qi, S., Zhang, X., Fu, Z., Pi, A., Shi, F., Fan, Y., Zhang, J., Xiao, T., Shang, D., Lin, M., Gao, N., Chang, J., & Gao, Y.
PMID: 35935850
应用:
反应种属:
发表时间: 2022 Jul
-
Citation
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Naringenin Regulates FKBP4/NR3C1/NRF2 Axis in Autophagy and Proliferation of Breast Cancer and Differentiation and Maturation of Dendritic Cell
Author: Xiong, H., Chen, Z., Lin, B., Xie, B., Liu, X., Chen, C., Li, Z., Jia, Y., Wu, Z., Yang, M., Jia, Y., Wang, L., Zhou, J., & Meng, X.
PMID: 35087512
应用:
反应种属: Human
发表时间: 2022 Jan
-
Citation
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A nanotherapeutic strategy to overcome chemoresistance to irinotecan/7-ethyl-10-hydroxy-camptothecin in colorectal cancer
Author:
PMID: 34718178
应用: WB
反应种属: Mouse
发表时间: 2022 Jan
-
Citation
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Comprehensive analysis of FKBP4/NR3C1/TMEM173 signaling pathway in triple-negative breast cancer cell and dendritic cell among tumor microenvironment
Author: Xiong, H., Chen, Z., Lin, B., Chen, W., Li, Q., Li, Y., Fang, M., Wang, Y., Zhang, H., Lu, Y., Bi, A., Wu, S., Jia, Y., & Wang, X.
PMID: 35118194
应用: WB
反应种属: Human
发表时间: 2022 Jan
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Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice
Author: Deng, L. D., Qi, L., Suo, Q., Wu, S. J., Mamtilahun, M., Shi, R. B., Liu, Z., Sun, J. F., Tang, Y. H., Zhang, Z. J., Yang, G. Y., & Wang, J. X.
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反应种属: Mouse
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A Subunit of the COP9 Signalosome, MoCsn6, Is Involved in Fungal Development, Pathogenicity, and Autophagy in Rice Blast Fungus
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PMID: 36445131
应用: WB
反应种属: M. Oryzae
发表时间: 2022 Dec
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The Ethanolic Extract of Lindera aggregata Modulates Gut Microbiota Dysbiosis and Alleviates Ethanol-Induced Acute Liver Inflammation and Oxidative Stress SIRT1/Nrf2/NF- κ B Pathway
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PMID: 36583098
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反应种属:
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Nicotinamide Mononucleotide Ameliorates Silica-Induced Lung Injury through the Nrf2-Regulated Glutathione Metabolism Pathway in Mice
Author: Wang, L., Zhao, M., Qian, R., Wang, M., Bao, Q., Chen, X., Du, W., Zhang, L., Ye, T., Xie, Y., Zhang, B., Peng, L., & Yao, Y.
PMID: 36615800
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反应种属: Mouse
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Suppressive effects of pterostilbene on human cytomegalovirus (HCMV) infection and HCMV-induced cellular senescence
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PMID: 36564838
应用: WB
反应种属: Human
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Bulk RNA-seq and scRNA-seq analysis reveal an activation of immune response and compromise of secretory function in major salivary glands of obese mice
Author: Huang, H., Gao, C., Wang, S., Wu, F., Wei, J., & Peng, J.
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反应种属: Mouse
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Sodium butyrate alleviates deoxynivalenol-induced hepatic cholesterol metabolic dysfunction via RORγ-mediated histone acetylation modification in weaning piglets
Author: Zong, Q., Qu, H., Zhao, Y., Liu, H., Wu, S., Wang, S., Bao, W., & Cai, D.
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反应种属: Pig
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Iron supplementation inhibits hypoxia-induced mitochondrial damage and protects zebrafish liver cells from death
Author: Hu, R., Li, G., Xu, Q., & Chen, L.
PMID: 36091397
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反应种属: Zebrafish
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Remote ischemic preconditioning protects against cerebral ischemia injury in rats by upregulating miR-204-5p and activating the PINK1/Parkin signaling pathway
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Transplantion of predominant Lactobacilli from native hens to commercial hens could indirectly regulate their ISC activity by improving intestinal microbiota
Author: Liu, L., Zhou, Z., Hong, Y., Jiang, K., Yu, L., Xie, X., Mi, Y., Zhu, S. J., Zhang, C., & Li, J.
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Jujuboside B Inhibits the Proliferation of Breast Cancer Cell Lines by Inducing Apoptosis and Autophagy
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A. Muciniphila Suppresses Colorectal Tumorigenesis by Inducing TLR2/NLRP3-Mediated M1-Like TAMs
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反应种属: Mouse
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The balance between AIM2-associated inflammation and autophagy: the role of CHMP2A in brain injury after cardiac arrest
Author: Shao, R., Wang, X., Xu, T., Xia, Y., & Cui, D.
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反应种属: Rat
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Nano-Sized Hydroxyapatite Induces Apoptosis and Osteogenic Differentiation of Vascular Smooth Muscle Cells via JNK/c-JUN Pathway. International journal of nanomedicine, 16, 3633–3648.
Author: Liu, Q., Xiang, P., Chen, M., Luo, Y., Zhao, Y., Zhu, J., Jing, W., & Yu, H.
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反应种属: Human
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<html>Curcumin prevents obesity by targeting TRAF4-induced ubiquitylation in m<sup>6</sup> A-dependent manner. EMBO reports, 22(5), e52146.</html>
Author: Chen, Y., Wu, R., Chen, W., Liu, Y., Liao, X., Zeng, B., Guo, G., Lou, F., Xiang, Y., Wang, Y., & Wang, X.
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反应种属: Mouse
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Unique and complementary suppression of cGAS-STING and RNA sensing- triggered innate immune responses by SARS-CoV-2 proteins. Signal transduction and targeted therapy, 6(1), 123.
Author: Rui, Y., Su, J., Shen, S., Hu, Y., Huang, D., Zheng, W., Lou, M., Shi, Y., Wang, M., Chen, S., Zhao, N., Dong, Q., Cai, Y., Xu, R., Zheng, S., & Yu, X. F.
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反应种属: Human
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Bacterial infection reinforces host metabolic flux from arginine to spermine for NLRP3 inflammasome evasion. Cell reports, 34(10), 108832.
Author: Jiang, J., Wang, W., Sun, F., Zhang, Y., Liu, Q., & Yang, D.
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反应种属: Mouse
发表时间: 2021 Mar
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Mesenchymal stem cells desensitize castration-resistant prostate cancer to docetaxel chemotherapy via inducing TGF-β1-mediated cell autophagy
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Keratin 1 plays significant roles in maintaining the survival and oxidative stress state of B16-F10 melanoma cell lines. International journal of physiology, pathophysiology and pharmacology, 13(1), 12–16.
Author: Li, Y., Zhang, M., & Ying, W.
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Activation of GPR120 in podocytes ameliorates kidney fibrosis and inflammation in diabetic nephropathy
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反应种属: Mouse
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Natural flavonoid pectolinarigenin alleviated kidney fibrosis via inhibiting the activation of TGFβ/SMAD3 and JAK2/STAT3 signaling. International immunopharmacology, 91, 107279.
Author: Li, Y., Guo, F., Huang, R., Ma, L., & Fu, P.
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反应种属: Mouse
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Leptin Gene Protects Against Cold Stress in Antarctic Toothfish
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应用: ICC
反应种属:
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AMPK-PINK1/Parkin Mediated Mitophagy Is Necessary for Alleviating Oxidative Stress-Induced Intestinal Epithelial Barrier Damage and Mitochondrial Energy Metabolism Dysfunction in IPEC-J2
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The Antioxidant Phytochemical Schisandrin A Promotes Neural Cell Proliferation and Differentiation after Ischemic Brain Injury
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Integrative omic analysis reveals the improvement of alkaloid accumulation by ultraviolet-B radiation and its upstream regulation in Catharanthus roseus
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反应种属:
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Fraxinellone Has Anticancer Activity by Inducing Osteosarcoma Cell Apoptosis via Promoting Excessive Autophagy Flux
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应用: WB
反应种属: mice
发表时间: 2021 Apr
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Functional regulation of an ancestral RAG transposon ProtoRAG by a trans-acting factor YY1 in lancelet
Author: Shaochun Yuan;Anlong Xu
PMID: 32908127
应用: WB
反应种属: amphioxus
发表时间: 2020 Sep
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Spinal TLR4/P2X7 Receptor-Dependent NLRP3 Inflammasome Activation Contributes to the Development of Tolerance to Morphine-Induced Antinociception
Author: Tao Xu;Aizhong Wang
PMID: 33061523
应用: WB
反应种属: mice
发表时间: 2020 Sep
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lncRNA OTUD6B-AS1 Exacerbates As2O3-Induced Oxidative Damage in Bladder Cancer via miR-6734-5p-Mediated Functional Inhibition of IDH2
Author: Shuhua Xi
PMID: 32952848
应用: WB
反应种属: human
发表时间: 2020 Sep
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Chronic morphine induces cyclic adenosine monophosphate formation and hyperpolarization-activated cyclic nucleotide-gated channel expression in the spinal cord of mice
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反应种属: Mouse
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Water extract of sporoderm-broken spores of Ganoderma lucidum enhanced pd-l1 antibody efficiency through downregulation and relieved complications of pd-l1 monoclonal antibody
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反应种属: Mouse
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Pharmacological inhibition of fatty acid-binding protein 4 alleviated kidney inflammation and fibrosis in hyperuricemic nephropathy
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CD44 inhibition attenuates EGFR signaling and enhances cisplatin sensitivity in human EGFR wild-type non-small-cell lung cancer cells
Author: Dandan Yuan;Mingxing Li
PMID: 32236608
应用: WB,IF
反应种属: human
发表时间: 2020 Jun
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Disabling phosphorylation at the homer ligand of the metabotropic glutamate receptor 5 alleviates complete Freund's adjuvant-induced inflammatory pain
Author: Tao Xu
PMID: 32156549
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反应种属: mice
发表时间: 2020 Jun
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Autophagy negative-regulating Wnt signaling enhanced inflammatoryosteoclastogenesis from Pre-OCsin vitro
Author: Weilian Sun
PMID: 32199225
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反应种属: human
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Activation of GPR120 by TUG891 ameliorated cisplatin-induced acutekidney injury via repressing ER stress and apoptosis
Author: Liang Ma;Ping Fu
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反应种属: mice
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p53 isoform Δ113p53 promotes zebrafish heart regeneration by maintaining redox homeostasis
Author: Wei-Qiang Tan;Jun Chen
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反应种属: Zebrafish
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STAT3 enhances radiation-induced tumor migration,invasion and stem-like properties of bladder cancer
Author: Zhaolu Kong
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反应种属: human
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2-Methylquinazoline derivative 23BB as a highly selective histone deacetylase 6 inhibitor alleviated cisplatin-induced acute kidney injury
Author: Liang Ma
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反应种属: mice
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Increased FURIN expression in rheumatoid arthritis patients and its anti-inflammatory effect
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Ganoderma Lucidum Polysaccharides Ameliorates Hepatic Steatosis and Oxidative Stress in db/db Mice via Targeting Nuclear Factor E2 (Erythroid-Derived 2)-Related Factor-2/Heme Oxygenase-1 (HO-1) Pathway
Author: Dan Qing Chen
PMID: 32245940
应用: IHC
反应种属: mouse
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Identification of CD206 as a potential biomarker of cancer stem-like cells and therapeutic agent in liver cancer
Author: Lifen Zhu,Shibing Wang
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反应种属: human
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One-Carbon Metabolism Supports SAdenosylmethionine and Histone Methylation to Drive Inflammatory Macrophages
Author: Yingliang Wu,Di Wang
PMID: 31420217
应用: WB
反应种属: human
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Regular Swimming Exercise Attenuated Neuroma Pain in Rats: Involvement of Leptin and Adiponectin.
Author: Dongping Du
PMID: 30986512
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反应种属: rat
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Pharmacological and genetic inhibition of fatty acid‐binding protein 4 alleviated cisplatin‐induced acute kidney injury
Author: Liang Ma,Ping Fu
PMID: 31286669
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反应种属: mice
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Wnt Signaling Modulates Routes of Retinoic Acid-Induced Differentiation of Embryonic Stem Cells.
Author: Ming Zhang,Liangbiao Chen
PMID: 31337269
应用: WB,IS
反应种属: Embryonic Stem Cells
发表时间: 2019 Oct
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Bmal1 regulates circadian expression of cytochrome P450 3a11 and drug metabolism in mice
Author: Baojian Wu
PMID: 31633069
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反应种属: mice
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Inhibition of neuronal ferroptosis in the acute phase of intracerebral hemorrhage shows long-term cerebroprotective effects.
Author: Hanbing Shang
PMID: 31442590
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反应种属: mice
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Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAVS
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Lipofectamine 2000/siRNA complexes cause endoplasmic reticulum unfolded protein response in human endothelial cells. Journal of cellular physiology, 234(11), 21166–21181.
Author: Jinliang Nan,Yinuo Lin
PMID: 31032939
应用: WB,IF
反应种属: Human coronary artery endothelial cells (HCAECs)
发表时间: 2019 Nov
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Identification of angiogenesis-inhibiting peptides from Chan Su
Author: Fei Gao;Yongchang Qian
PMID: 31252070
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反应种属: human
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Curcumin modulates the apolipoprotein B mRNA editing by coordinating the expression of cytidine deamination to uridine editosome components in primary mouse hepatocytes
Author: Nan Tian
PMID: 31080349
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反应种属: mice
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ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome
Author: Jianli Jiang,Ping Zhu
PMID: 30911117
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反应种属: human
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Effect of lincRNA-p21 targeting HIF-1α on biological functions of liver cancer cells
Author: Dr Wenbin Li
PMID: 31186706
应用: WB
反应种属: mice
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Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer
Author: Dr Shibing Wang
PMID: 30365143
应用: WB
反应种属: human
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m6A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner
Author: Xinxia Wang
PMID: 30787270
应用: WB
反应种属: porcine
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Tailored monoclonal antibody as recognition probe of immunosensor for ultrasensitive detection of silk fibroin and use in the study of archaeological samples
Author: Yang Zhou;Bing Wang
PMID: 31550631
应用: ELISA
反应种属: raw silk
发表时间: 2019 Dec
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Water Extract of Sporoderm-Broken Spores of Ganoderma lucidum Induces Osteosarcoma Apoptosis and Restricts Autophagic Flux
Author: Weiqi Yan
PMID: 32021244
应用: WB,IHC
反应种属: mice
发表时间: 2019 Dec
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Development of a Highly Efficient Hybrid Peptide That Increases Immunomodulatory Activity Via the TLR4-Mediated Nuclear Factor-κB Signaling Pathway
Author: Rijun Zhang
PMID: 31817671
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反应种属: mice
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Design and Development of a Novel Peptide for Treating Intestinal Inflammation
Author: Rijun Zhang
PMID: 31447849
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反应种属: mice
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PARK2 Suppresses Proliferation and Tumorigenicity in Non-small Cell Lung Cancer
Author: Chi Pan,Suzhan Zhang
PMID: 31508359
应用: WB
反应种属: Human NSCLC tissue
发表时间: 2019 Aug
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Lysosomal integral membrane protein-2 (LIMP-2/ SCARB2) is involved in lysosomal cholesterol export
Author: Sergio Grinstein,Elina Ikonen,Paul Saftig,Dante Neculai
PMID: 31387993
应用: WB
反应种属: A431 cells and MEFs
发表时间: 2019 Aug
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Mitophagy is activated in brain damage induced by cerebral ischemia and reperfusion via the PINK1/Parkin/p62 signalling pathway
Author: zhangyong
PMID: 29964088
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反应种属: rat
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LMO3 promotes hepatocellular carcinoma invasion,metastasis and anoikis inhibition by directly interacting with LATS1 and suppressing Hippo signaling
Author: Baobing Yin
PMID: 30219064
应用: IHC,WB
反应种属: human
发表时间: 2018 Sep
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Decreased CRHBP expression is predictive of poor prognosis in patients with hepatocellular carcinoma
Author: Dong-Sheng Huang
PMID: 30127978
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反应种属: human
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PARK2 inhibits osteosarcoma cell growth through the JAK2/STAT3/VEGF signaling pathway
Author: Suzhan Zhang,Weiqi Yan
PMID: 29515107
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反应种属: human,mouse
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OSMR gene effect on the pathogenesis of chronic autoimmune Urticaria via the JAK/STAT3 pathway
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反应种属: Human
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Xiao-Xu-Ming Decoction Reduced Mitophagy Activation andImproved Mitochondrial Function in Cerebral Ischemia andReperfusion Injury
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反应种属: Rat
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Expression of PIM-1 in salivary gland adenoid cystic carcinoma: Association with tumor progression and patients' prognosis
Author: Minghua Ge
PMID: 29399171
应用: WB
反应种属: human
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bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats
Author: Wei Jiang,Derong Cui
PMID: 29416039
应用: WB
反应种属: rats
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Expression Pattern of Tumor Necrosis Factor-α–Induced Protein 8-Like 2 in Acute Rejection of Cardiac Allograft
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反应种属: Mouse
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Hypoxia Response Element-Regulated MMP-9 Promotes Neurological Recovery via Glial Scar Degradation and Angiogenesis in Delayed Stroke
Author: ZhijunZhang,Guo-Yuan Yang
PMID: 28396199
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反应种属: mice
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Effects of unfractionated heparin and rivaroxaban on the expression of heparanase and fibroblast growth factor 2 in human osteoblasts
Author: Xia, J., Sheng, W., Pei, L., Li, N., Zhang, Z., Wang, J., Zu, J., Wang, N., & Wang, D.
PMID: 28498476
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反应种属: Human,Rat
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The dietary polysaccharide from Ommastrephes bartrami prevents chemotherapeutic mucositis by promoting the gene expression of antimicrobial peptides in Paneth cells
Author: Qing-Juan Tang
PMID: NoPMID5
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反应种属: Mouse
发表时间: 2017 Jan
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Administration of erythropoietin prevents bone loss in osteonecrosis of the femoral head in mice
Author: Chengliang Wu
PMID: 29039481
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反应种属: mice
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N-myc downstream regulated gene 1(NDRG1) promotes the stem-like properties of lung cancer cells through stabilized c-Myc
Author: Wang K
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A peptidoglycan recognition protein acts in whitefly (Bemisia tabaci) immunity and involves in Begomovirus acquisition
Author: Xue-Xin Chen
PMID: 27892529
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反应种属: B. tabaci MEAM1
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Farnesyl pyrophosphate synthase inhibitor,ibandronate,improves endothelial function in spontaneously hypertensive rats
Author: SHEN-JIANG HU
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Porcine lactoferrin-derived peptide LFP-20 protects intestinal barrier by maintaining tight junction complex and modulating inflammatory response
Author: Wang Y
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Placental NRP1 and VEGF expression in pre-eclamptic women and in a homocysteine-treated mouse model of pre-eclampsia
Author: Cheng WW
PMID: 26708340
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PFR peptide,one of the antimicrobial peptides identified from the derivatives of lactoferrin,induces necrosis in leukemia cells
Author: Cai-Yun Fu
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Proteasome inhibitor lactacystin enhances cisplatin cytotoxicity by increasing endoplasmic reticulum stress-associated apoptosis in HeLa cells
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反应种属: human
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HER4 is a novel prognostic biomarker in gastrointestinal stromal tumor specifically originated from stomach
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Regulation of SIRT2 levels for human non-small cell lung cancer therapy
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Acetylation of Chromatin-Associated Histone H3 Lysine 56 Inhibits the Development of Encysted Artemia Embryos
Author: Wei-Jun Yang
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Male contraceptive Adjudin is a potential anti-cancer drug
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Role of DNA Methylation in Cell Cycle Arrest Induced by Cr (VI) in Two Cell Lines
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Exchange protein activated by cyclic adenosine monophosphate regulates the switch between adipogenesis and osteogenesis of human mesenchymal stem cells through increasing the activation of phosphatidylinositol 3-kinase
Author: Tong X.
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Extracellular signal-regulated kinase1/2 activated by fluid shear stress promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells through novel signaling pathways
Author: Wang J
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An i-type lysozyme from the Asiatic hard clam Meretrix meretrix potentially functioning in host immunity
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Astrocyte activation and memory impairment in the repetitive febrile seizures model
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Leukemia inhibitory factor prevents chicken follicular atresia through PI3K/AKT and Stat3 signaling pathways.
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